Patents by Inventor John Anthony Hardy

John Anthony Hardy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Test and model for Alzheimer's disease
    Publication number: 20030165958
    Abstract: Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
    Type: Application
    Filed: February 3, 2003
    Publication date: September 4, 2003
    Applicant: Elan Pharmaceuticals
    Inventors: John Anthony Hardy, Marie-Christine Chartier-Harlin, Alison Mary Goate, Michael John Owen, Michael John Mullan
  • Transgenic mouse expressing an APP-FAD DNA sequence
    Patent number: 6300540
    Abstract: Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 9, 2001
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: John Anthony Hardy, Marie-Christine Chartier-Harlin, Alison Mary Goate, Michael John Owen, Michael John Mullan
  • APP770 mutant in alzheimer's disease
    Patent number: 5877015
    Abstract: Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: March 2, 1999
    Assignee: Imperial College of Science, Technology of Medicine
    Inventors: John Anthony Hardy, Marie-Christine Chartier-Harlin, Alison Mary Goate, Michael John Owen, Michael John Mullan