Patents by Inventor John Asplin

John Asplin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190216756
    Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.
    Type: Application
    Filed: March 27, 2019
    Publication date: July 18, 2019
    Applicant: University of Houston System
    Inventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
  • Patent number: 10285961
    Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: May 14, 2019
    Assignee: University of Houston System
    Inventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
  • Patent number: 10258645
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: April 16, 2019
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20180169144
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: February 15, 2018
    Publication date: June 21, 2018
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9895396
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: February 20, 2018
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20170340664
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: August 21, 2017
    Publication date: November 30, 2017
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9737564
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: August 22, 2017
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20160184349
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: March 7, 2016
    Publication date: June 30, 2016
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9278112
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 8, 2016
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Publication number: 20150297545
    Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.
    Type: Application
    Filed: April 27, 2015
    Publication date: October 22, 2015
    Applicant: University of Houston System
    Inventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
  • Publication number: 20150216825
    Abstract: In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium oxalate crystal growth. In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium phosphate crystal growth. In some embodiments, such a composition comprises at least one citrate derivative of an organic acid and at least one pharmaceutically acceptable carrier. In another embodiment, the present disclosure relates to a method of controlling calcium oxalate crystal growth in a subject in need thereof. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease.
    Type: Application
    Filed: February 6, 2015
    Publication date: August 6, 2015
    Applicant: University of Houston System
    Inventors: Jeffrey D. Rimer, John Asplin
  • Publication number: 20140271929
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: David S. GOLDFARB, Brian EISNER, John ASPLIN, Marshall L. STOLLER
  • Publication number: 20070284286
    Abstract: The present invention relates to a process and apparatus for recovering product from reactor effluent of a reactor for a hydrocarbon feedstream. An indigenous C4 stream is used as lean oil in a demethanizer, which facilitates significant cost and operational savings. C4 bottoms from a downstream depropanizer is used as lean oil recycle.
    Type: Application
    Filed: August 16, 2007
    Publication date: December 13, 2007
    Inventors: David Duhon, John Asplin
  • Publication number: 20070007170
    Abstract: A method is disclosed for treating gaseous effluent from a hydrocarbon pyrolysis unit to provide steam cracked tar of reduced asphaltene and toluene insolubles content. The method is suitable for preparing reduced viscosity tar useful as a fuel blending stock, or feedstock for producing carbon black, while reducing or eliminating the need for externally sourced lighter aromatics additives to meet viscosity specifications. The method comprises drawing steam cracked tar from a separation vessel, e.g., a primary fractionator or tar knock-out drum, cooling the tar, and returning it to the separation vessel to effect lower overall tar temperatures within the separation vessel, in order to reduce viscosity increasing condensation reactions. An apparatus for carrying out the method is also provided.
    Type: Application
    Filed: July 8, 2005
    Publication date: January 11, 2007
    Inventors: Robert Strack, Richard Stell, John Messinger, Dane Grenoble, John Asplin
  • Publication number: 20050033103
    Abstract: The present invention provides new highly-efficient separation processes and systems for separating polymerization-grade ethylene and propylene from an initial effluent stream comprising ethane, ethylene, propylene, dimethyl ether, and one or more of propane, acetylene, methyl acetylene, propadiene, methane, hydrogen, carbon monoxide, carbon dioxide and C4+ components. In one embodiment, the initial effluent stream is provided from a methanol-to-olefin reaction system. It has been discovered that an efficient separation of these components is realized when DME is partially removed in a first separation step comprising methanol and water washing steps, followed by separation of the remaining components in additional separation steps.
    Type: Application
    Filed: August 6, 2003
    Publication date: February 10, 2005
    Inventors: Cornelis Van Egmond, David Duhon, John Asplin
  • Publication number: 20050033104
    Abstract: The present invention provides new highly-efficient separation processes and systems for separating polymerization-grade ethylene and propylene from an initial effluent stream comprising ethane, ethylene, propylene, dimethyl ether, and one or more of propane, acetylene, methyl acetylene, propadiene, methane, hydrogen, carbon monoxide, carbon dioxide and C4+ components. In one embodiment, the initial effluent stream is provided from a methanol-to-olefin reaction system. It has been discovered that an efficient separation of these components is realized when DME is partially removed in a first separation step comprising methanol and water washing steps, followed by separation of the remaining components in additional separation steps.
    Type: Application
    Filed: July 30, 2004
    Publication date: February 10, 2005
    Inventors: Cor van Egmond, David Duhon, John Asplin