Patents by Inventor John Asplin
John Asplin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190216756Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.Type: ApplicationFiled: March 27, 2019Publication date: July 18, 2019Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
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Patent number: 10285961Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.Type: GrantFiled: April 27, 2015Date of Patent: May 14, 2019Assignee: University of Houston SystemInventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
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Patent number: 10258645Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: GrantFiled: February 15, 2018Date of Patent: April 16, 2019Assignees: New York University, General Hospital Corporation, The Regents of the University of CaliforniaInventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Publication number: 20180169144Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: ApplicationFiled: February 15, 2018Publication date: June 21, 2018Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Patent number: 9895396Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: GrantFiled: August 21, 2017Date of Patent: February 20, 2018Assignees: New York University, General Hospital Corporation, The Regents of the University of CaliforniaInventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Publication number: 20170340664Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: ApplicationFiled: August 21, 2017Publication date: November 30, 2017Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Patent number: 9737564Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: GrantFiled: March 7, 2016Date of Patent: August 22, 2017Assignees: New York University, General Hospital Corporation, The Regents of the University of CaliforniaInventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Publication number: 20160184349Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: ApplicationFiled: March 7, 2016Publication date: June 30, 2016Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Patent number: 9278112Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: GrantFiled: March 14, 2014Date of Patent: March 8, 2016Assignees: New York University, General Hospital Corporation, The Regents of the University of CaliforniaInventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
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Publication number: 20150297545Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.Type: ApplicationFiled: April 27, 2015Publication date: October 22, 2015Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
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Publication number: 20150216825Abstract: In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium oxalate crystal growth. In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium phosphate crystal growth. In some embodiments, such a composition comprises at least one citrate derivative of an organic acid and at least one pharmaceutically acceptable carrier. In another embodiment, the present disclosure relates to a method of controlling calcium oxalate crystal growth in a subject in need thereof. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease.Type: ApplicationFiled: February 6, 2015Publication date: August 6, 2015Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, John Asplin
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Publication number: 20140271929Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Inventors: David S. GOLDFARB, Brian EISNER, John ASPLIN, Marshall L. STOLLER
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Publication number: 20070284286Abstract: The present invention relates to a process and apparatus for recovering product from reactor effluent of a reactor for a hydrocarbon feedstream. An indigenous C4 stream is used as lean oil in a demethanizer, which facilitates significant cost and operational savings. C4 bottoms from a downstream depropanizer is used as lean oil recycle.Type: ApplicationFiled: August 16, 2007Publication date: December 13, 2007Inventors: David Duhon, John Asplin
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Publication number: 20070007170Abstract: A method is disclosed for treating gaseous effluent from a hydrocarbon pyrolysis unit to provide steam cracked tar of reduced asphaltene and toluene insolubles content. The method is suitable for preparing reduced viscosity tar useful as a fuel blending stock, or feedstock for producing carbon black, while reducing or eliminating the need for externally sourced lighter aromatics additives to meet viscosity specifications. The method comprises drawing steam cracked tar from a separation vessel, e.g., a primary fractionator or tar knock-out drum, cooling the tar, and returning it to the separation vessel to effect lower overall tar temperatures within the separation vessel, in order to reduce viscosity increasing condensation reactions. An apparatus for carrying out the method is also provided.Type: ApplicationFiled: July 8, 2005Publication date: January 11, 2007Inventors: Robert Strack, Richard Stell, John Messinger, Dane Grenoble, John Asplin
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Publication number: 20050033103Abstract: The present invention provides new highly-efficient separation processes and systems for separating polymerization-grade ethylene and propylene from an initial effluent stream comprising ethane, ethylene, propylene, dimethyl ether, and one or more of propane, acetylene, methyl acetylene, propadiene, methane, hydrogen, carbon monoxide, carbon dioxide and C4+ components. In one embodiment, the initial effluent stream is provided from a methanol-to-olefin reaction system. It has been discovered that an efficient separation of these components is realized when DME is partially removed in a first separation step comprising methanol and water washing steps, followed by separation of the remaining components in additional separation steps.Type: ApplicationFiled: August 6, 2003Publication date: February 10, 2005Inventors: Cornelis Van Egmond, David Duhon, John Asplin
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Publication number: 20050033104Abstract: The present invention provides new highly-efficient separation processes and systems for separating polymerization-grade ethylene and propylene from an initial effluent stream comprising ethane, ethylene, propylene, dimethyl ether, and one or more of propane, acetylene, methyl acetylene, propadiene, methane, hydrogen, carbon monoxide, carbon dioxide and C4+ components. In one embodiment, the initial effluent stream is provided from a methanol-to-olefin reaction system. It has been discovered that an efficient separation of these components is realized when DME is partially removed in a first separation step comprising methanol and water washing steps, followed by separation of the remaining components in additional separation steps.Type: ApplicationFiled: July 30, 2004Publication date: February 10, 2005Inventors: Cor van Egmond, David Duhon, John Asplin