Abstract: A ball valve assembly includes a ball configured to rotate between an open position and a closed position. The ball valve assembly also includes a cradle having a ball-facing surface. The ball-facing surface faces the ball and is positioned at an end of a fluid passage through the cradle. In addition, the cradle is configured to rotatably support the ball to enable the ball to rotate between the open position and the closed position, and the cradle is configured to block movement of the ball toward the ball-facing surface to establish a separation distance between the ball and the ball-facing surface.

Abstract: Systems and methods which provide tokenization of various shipping data for which shielding is desired are described. Embodiments may facilitate controlled and/or protected usage of shielded shipping data, such as may include personally identifiable information, with tokenization. Shielded shipping data tokens of embodiments are matched with an entity, party, system, permitted usage of corresponding shielded shipping data. A data shielding service system may shield usage of shielded shipping data in accordance with applicable regulations according to applicable rules, and/or the like. Permitted accessors may be relieved of demands of maintaining compliance with the regulations and rules with respect to shielded shipping data in light of their enforcement and compliance being imposed through tokenization of the shielded shipping data.

Abstract: Exemplary embodiments of the present invention would determine exemplary projected routes, delivery dates, times and rates for multiple carriers and multiple delivery services/methods. Exemplary embodiments would generate and provide an exemplary interactive graphic comparison mapping of the exemplary projected carrier-specific, delivery-service-specific routes, and associated projected delivery dates, times and rates. Exemplary embodiments of the present invention would generate and provide an exemplary interactive graphic mapping of a projected carrier-specific, delivery-service-specific route, and associated projected delivery date, time and rate for a user-selected carrier and delivery service/method. Exemplary embodiments of the present invention would then track shipping/mailing progress and delivery status of the item according to carrier-provided shipping/mailing progress and delivery status “events,” such as, for example, carrier-provided item scanning events.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: Apparatuses, methods, systems, and program products are disclosed for secure data handling and storage. An apparatus includes a lock module that receives a request to decrypt encrypted data that is stored in a data repository, the encrypted data encrypted using a first encryption key, and unlocks an encryption engine in response to the request. An encryption engine may be unlocked using a master key that is generated based on combination of a plurality of keys held by a plurality of key holders. An apparatus includes a decryption module that decrypts encrypted data using an encryption engine. Encrypted data may be decrypted using a first encryption key. An apparatus includes an encryption module that re-encrypts decrypted data using an encryption engine. Decrypted data may be re-encrypted with a second encryption key that is different than a first encryption key and stored in a data repository.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: A rotary bit configured to deburr and swage an end of a tube, comprising a first end configured to deburr and swage the end of the tube, and a second end configured to be secured to a rotary device, wherein the first end includes a plurality of blades that extend axially along the first end and radially outward from the rotary bit, the plurality of blades including a plurality of leading blades and a plurality of finishing blades, the leading blades configured to initially deburr and swage the end of the tube upon insertion of the rotary bit into the end of the tube, and the finishing blades configured to complete deburring and swaging of the end of the tube, the finishing blades extending radially outward from the rotary bit to a greater extent than the leading blades.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: A rotary bit configured to deburr and swage an end of a tube, comprising a first end configured to deburr and swage the end of the tube, and a second end configured to be secured to a rotary device, wherein the first end includes a plurality of blades that extend axially along the first end and radially outward from the rotary bit, the plurality of blades including a plurality of leading blades and a plurality of finishing blades, the leading blades configured to initially deburr and swage the end of the tube upon insertion of the rotary bit into the end of the tube, and the finishing blades configured to complete deburring and swaging of the end of the tube, the finishing blades extending radially outward from the rotary bit to a greater extent than the leading blades.

Abstract: Exemplary embodiments of the present invention would determine exemplary projected routes, delivery dates, times and rates for multiple carriers and multiple delivery services/methods. Exemplary embodiments would generate and provide an exemplary interactive graphic comparison mapping of the exemplary projected carrier-specific, delivery-service-specific routes, and associated projected delivery dates, times and rates. Exemplary embodiments of the present invention would generate and provide an exemplary interactive graphic mapping of a projected carrier-specific, delivery-service-specific route, and associated projected delivery date, time and rate for a user-selected carrier and delivery service/method. Exemplary embodiments of the present invention would then track shipping/mailing progress and delivery status of the item according to carrier-provided shipping/mailing progress and delivery status “events,” such as, for example, carrier-provided item scanning events.

Abstract: A connection joint for coupling a pair of conduits. The connection joint includes a tubular body having an inlet end and an outlet end that are each configured for receipt of a respective conduit therein. A first membrane seal is located within the tubular body and spaced apart from the inlet end, and a second membrane seal is located within the tubular body and spaced apart from the outlet end. The first and second membrane seals each have a bulbous portion located proximate the inlet end and outlet end, respectively, a tubular sleeve unitary with the bulbous portion located away from the inlet end and outlet end, respectively, and a plurality of radially inwardly extending ribs.

Abstract: The present invention is directed to pyrazole derivatives, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: According to an aspect of the invention, there is provided a communication system for communicating between a ranged weapon and a projectile for that ranged weapon, the system comprising: a transmitter associated with the ranged weapon, the transmitter being arranged to encode data to be transmitted to the projectile on an electromagnetic carrier wave, and to transmit that electromagnetic carrier wave to the projectile; a receiver associated with the projectile, the receiver being arranged to receive the electromagnetic carrier wave, and to decode data encoded in the electromagnetic carrier wave to retrieve that data, the data being usable in the activation of a fuse of the projectile.

Abstract: The present invention is directed to pyridyl derivatives which are bromodomain inhibitors, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases or conditions.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: Compounds of formula (I): wherein X, Y, R1 and R3-R11 are as herein defined, and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis.