Patents by Inventor John B. Ancsin

John B. Ancsin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR CHARACTERIZATION OF HYPERTRIGLYCERIDEMIA
    Publication number: 20180179574
    Abstract: Provided herein are systems (e.g., reagents, devices, etc.) and methods for characterization of hypertriglyceridemia (HTG) in a subject. In particular, systems and methods, are provided for identifying the specific deficiency(ies) leading to HTG, and selecting an appropriate strategy for the treatment of HTG based thereof.
    Type: Application
    Filed: September 2, 2016
    Publication date: June 28, 2018
    Inventor: John B. Ancsin
  • Compositions and methods for treating atherosclerosis
    Patent number: 8703698
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: April 22, 2014
    Assignee: The University of Chicago
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • METHODS AND COMPOSITIONS FOR PREDICTING RESPONSE TO GLP-1 ANALOGS
    Publication number: 20140107028
    Abstract: Methods and compositions are provided for evaluating a diabetic patient for treatment with an incretin-based therapy. In certain embodiments, evaluation is ongoing and the patient is evaluated at multiple times. In additional embodiments, a diabetic patient is treated with an incretin-based therapy after the patient has been evaluated for expression levels of GLP-1R in a biological sample. In some aspects, the biological sample is specifically a blood sample that has been enriched for peripheral blood monocytes.
    Type: Application
    Filed: March 12, 2013
    Publication date: April 17, 2014
    Inventors: Sindhu RAJAN, Louis H. Philipson, John B. Ancsin
  • Compositions and Methods for Treating Atherosclerosis
    Publication number: 20110268768
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Application
    Filed: November 19, 2010
    Publication date: November 3, 2011
    Applicant: Queen's University at Kingston
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • Compositions and Methods for Treating Atherosclerosis
    Publication number: 20100279926
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Application
    Filed: February 8, 2010
    Publication date: November 4, 2010
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • Compositions and methods for treating atherosclerosis
    Patent number: 7700544
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: April 20, 2010
    Assignee: Queens's University at Kingston
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • Compositions and Methods for Treating Atherosclerosis
    Publication number: 20080221028
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Application
    Filed: October 15, 2007
    Publication date: September 11, 2008
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • Compositions and methods for treating atherosclerosis
    Patent number: 7291590
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: November 6, 2007
    Assignee: Queen's University at Kingston
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
  • Compositions and methods for treating atherosclerosis
    Publication number: 20040265982
    Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
    Type: Application
    Filed: June 10, 2004
    Publication date: December 30, 2004
    Inventors: Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia