Abstract: A reversible paperboard container having a bottom panel, a front panel adjacent to and in foldable relationship with the bottom panel. A back panel is adjacent to and in foldable relationship with the bottom panel. A left side panel is adjacent to and in foldable relationship with the bottom panel, a right side panel is adjacent to and in foldable relationship with the bottom panel. A first top panel is adjacent to and in foldable relationship with the back panel, and a second top panel is adjacent to and in foldable relationship with the front panel. The first top panel includes a first adhesive strip to sealingly close the paperboard container into a closed configuration. A first tear-away strip is included on the first top panel to open the paperboard container from the closed configuration, and a second adhesive strip to sealingly close the paperboard container into a reversed, closed configuration.

Abstract: A reversible paperboard container having a bottom panel, a front panel adjacent to and in foldable relationship with the bottom panel. A back panel is adjacent to and in foldable relationship with the bottom panel. A left side panel is adjacent to and in foldable relationship with the bottom panel, a right side panel is adjacent to and in foldable relationship with the bottom panel. A first top panel is adjacent to and in foldable relationship with the back panel, and a second top panel is adjacent to and in foldable relationship with the front panel. The first top panel includes a first adhesive strip to sealingly close the paperboard container into a closed configuration. A first tear-away strip is included on the first top panel to open the paperboard container from the closed configuration, and a second adhesive strip to sealingly close the paperboard container into a reversed, closed configuration.

Abstract: A one-pot process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.

Abstract: A one-pot process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.

Abstract: A process for reducing the amount of cholesterol in an edible fat capable of being solubilized comprising the steps of:(a) providing an edible fat in a liquid state;(b) adding an ionic salt selected from the group consisting of CaBr.sub.2 and MgBr.sub.2 to and edible fat;(c) mixing said ionic salt and edible fat for a time sufficient to cause said ionic salt to react with cholesterol present in said edible fat and form a precipitate; and(d) removing said precipitate from said mixtureand the product produced by the process are disclosed. The process is capable of reducing cholesterol in edible fats by about 30% to about 100%.

Abstract: A process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride (.alpha.-APM(HCl)) is disclosed. .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.

Abstract: N-formyl-L-aspartic anhydride is prepared using a minimum excess of formic acid. Acetic anhydride and a C.sub.3 -C.sub.6 secondary alcohol are added to the reaction mixture to consume excess formic acid. The reaction is suitable for further reactions without modification.

Abstract: Alkylphosphate solvents are disclosed for use in an amino acid and amino acid ester enzymatic coupling process. .alpha.-Aspartylphenylalanine methyl ester and intermediates thereof are prepared enzymatically in an alkylphosphate solvent or cosolvent.

Abstract: This invention encompasses a method and intermediates for preparing a commercial sweetening agent, .alpha.-L-aspartyl-L-phenylalanine methyl ester. The process involves reacting L-aspartic acid with diketene to form N-acetoacetyl-L-aspartic acid which is converted to N-acetoacetyl-L-aspartic anhydride by reaction with acetic anhydride. N-acetoacetyl-L-aspartic anhydride is reacted with L-phenylalanine methyl ester to provide N-acetoacetyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester which is converted to .alpha.-L-aspartyl-L-phenylalanine methyl ester by reaction with hydroxylamine hydrochloride.

Abstract: An improved process for isolating organic compounds from crude product or reaction mixtures by dissolving said crude product or reaction mixture in a suitable solvent, contacting the resulting solution with a lithium salt to form a solid metal salt complex, separating, and thereafter recovering a pure product by decomposing the lithium salt complex.

Abstract: This invention encompasses a method and intermediates for preparing a commercial sweetening agent, .alpha.-L-aspartyl-L-phenylalanine methyl ester. The process involves reacting L-aspartic acid with diketene to form N-acetoacetyl-L-aspartic acid which is converted to N-acetoacetyl-L-aspartic anhydride by reaction with acetic anhydride. N-acetoacetyl-L-aspartic anhydride is reacted with L-phenylalanine methyl ester to provide N-acetoacetyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester which is converted to .alpha.-L-aspartyl-L-phenylalanine methyl ester by reaction with hydroxylamine hydrochloride.

Abstract: An improved process for isolating organic compounds from crude product or reaction mixtures by dissolving said crude product or reaction mixture in a suitable solvent, contacting the resulting solution with a lithium salt to form a solid metal salt complex, separating, and thereafter recovering a pure product by decomposing the lithium salt complex.

Abstract: This invention encompasses a method and intermediates for preparing a commercial sweetening agent, .alpha.-L-aspartyl-L-phenylalanine methyl ester. The process involves reacting L-aspartic acid with diketene to form N-acetoacetyl-L-aspartic acid which is converted to N-acetoacetyl-L-aspartic anhydride by reaction with acetic anhydride. N-acetoacetyl-L-aspartic anhydride is reacted with L-phenylalanine methyl ester to provide N-acetoacetyl-.alpha.-L-aspartyl-L-phenylalanine methyl ester which is converted to .alpha.-L-aspartyl-L-phenylalanine methyl ester by reaction with hydroxylamine hydrochloride.

Abstract: A new process utilizing certain novel intermediates for the preparation of 1-diphenylmethyl-4-(6-methyl-2-pyridylmethyleneamino)piperazine is described herein. The process utilizes readily available starting material and has the distinct advantage of having no N-nitroso intermediate in its procedure.

Abstract: Contacting of appropriately substituted nitrosobenzene with diphenylcyclopropenone under reflux conditions yields novel 2-aryl-3,4-diphenylisoxazolin-5-ones, which are useful as pharmacological agents in view of their serum triglyceride and cholesterol lowering properties.

Abstract: A fluid coupling for driving a cooling fan associated with a vehicle in a ram air stream. The coupling comprises relatively rotatable input and output members. The output member defines a chamber within which the input member rotates. The members have lands and grooves which define a shear space therebetween, and are cooperable with viscous shear fluid to transmit torque therebetween. The output member defines a reservoir chamber located forwardly of the lands and grooves in the ram air stream. An impact pumping ramp on the output member directs fluid from the shear space into the reservoir chamber during rotation of the input member. A temperature-responsive valve arrangement controls the flow of fluid from the reservoir chamber to the shear space. The output member has mounting pads against which fan blades are secured. The mounting pads are located axially on the output member between the lands and grooves, and the reservoir chamber and at least, in part, radially outwardly in the lands and grooves.