Patents by Inventor John B. Ohlrogge
John B. Ohlrogge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10570404Abstract: The application describes stabilized WRINKLED1 transcription factors, as well as nucleic acids, and expression cassettes that encode and express such stabilized WRINKLED1 transcription factors and that are useful for increasing production of oils in plants and seeds.Type: GrantFiled: June 30, 2016Date of Patent: February 25, 2020Assignee: Board of Trustees of Michigan State UniversityInventors: John B. Ohlrogge, Christoph Benning, Wei Ma, Que Kong
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Patent number: 10421975Abstract: The application describes plants, plant cells, and seeds that express WRINKLED1 transcription factors and/or 14-3-3 proteins that are useful for increasing production of oils in plants and seeds. Also described are expression systems and cassettes that encode and express such WRINKLED1 transcription factors and/or 14-3-3 proteins.Type: GrantFiled: June 19, 2017Date of Patent: September 24, 2019Assignee: Board of Trustees of Michigan State UniversityInventors: Christoph Benning, John B. Ohlrogge, Wei Ma, Que Kong
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Publication number: 20180094274Abstract: The application describes plants, plant cells, and seeds that express WRINKLED1 transcription factors and/or 14-3-3 proteins that are useful for increasing production of oils in plants and seeds. Also described are expression systems and cassettes that encode and express such WRINKLED1 transcription factors and/or 14-3-3 proteins.Type: ApplicationFiled: June 19, 2017Publication date: April 5, 2018Inventors: Christoph Benning, John B. Ohlrogge, Wei Ma, Que Kong
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Publication number: 20170002371Abstract: The application describes stabilized WRINKLED1 transcription factors, as well as nucleic acids, and expression cassettes that encode and express such stabilized WRINKLED1 transcription factors and that are useful for increasing production of oils in plants and seeds.Type: ApplicationFiled: June 30, 2016Publication date: January 5, 2017Inventors: John B. Ohlrogge, Christoph Benning, Wei Ma, Que Kong
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Patent number: 9006518Abstract: Disclosed are genetic constructs, transgenic plant cells and transgenic plants, as well as associated methods, for increasing oil production in a plant using F-box gene sequences.Type: GrantFiled: March 2, 2011Date of Patent: April 14, 2015Assignee: Board of Trustees of Michigan State UniversityInventors: John B. Ohlrogge, Sari A. Ruuska, Yonghua Li
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Publication number: 20120017340Abstract: Disclosed are genetic constructs, transgenic plant cells and transgenic plants, as well as associated methods, for increasing oil production in a plant using F-box gene sequences.Type: ApplicationFiled: March 2, 2011Publication date: January 19, 2012Inventors: John B. Ohlrogge, Sari A. Ruuska, Yonghua Li
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Patent number: 7932433Abstract: Cyclopropane fatty acid synthase genes and polypeptides are described. Plants are transformed with such genes to produce such polypeptides.Type: GrantFiled: October 7, 2008Date of Patent: April 26, 2011Assignee: Board of Trustees of Michigan State UniversityInventors: Xiaoming Bao, John B. Ohlrogge, Michael R. Pollard
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Patent number: 7915480Abstract: Disclosed are genetic constructs, transgenic plant cells and transgenic plants, as well as associated methods, for increasing oil production in a plant using F-box gene sequences.Type: GrantFiled: October 30, 2009Date of Patent: March 29, 2011Assignee: Board of Trustees of Michigan State UniversityInventors: John B. Ohlrogge, Sari A. Ruuska, Yonghua Li
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Patent number: 7868156Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: GrantFiled: July 14, 2008Date of Patent: January 11, 2011Assignee: Board of Trustees of Michigan State UniversityInventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Publication number: 20090100551Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: ApplicationFiled: July 14, 2008Publication date: April 16, 2009Inventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Patent number: 7446188Abstract: The present invention provides cyclopropane fatty acid synthase genes and proteins, and methods of their use. The present invention encompasses both native and recombinant wild-type forms of the synthase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type synthase. The present invention also provides methods of using cyclopropane fatty acid synthase genes and proteins, including in their expression in transgenic organisms and in the production of cyclopropane fatty acids in plant oils, and in particular seed oils.Type: GrantFiled: December 20, 2002Date of Patent: November 4, 2008Inventors: Xiaoming Bao, John B. Ohlrogge, Michael R. Pollard
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Patent number: 7405345Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: GrantFiled: July 18, 2006Date of Patent: July 29, 2008Assignee: Michigan State UniversityInventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Patent number: 7081565Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: GrantFiled: November 30, 2001Date of Patent: July 25, 2006Assignee: Board of Trustees Operating Michigan State UniversityInventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Publication number: 20030005485Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: ApplicationFiled: November 30, 2001Publication date: January 2, 2003Inventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Patent number: 6218600Abstract: The gene encoding a biotin carboxylase subunit of heteromeric ACCase has been isolated and sequenced. The cDNA sequence and deduced amino acid sequence is set forth in FIG. 1 and has been accorded GenBank Accession No. L38260. By controlling expression of the gene of the present invention, carboxylation of acetyl-CoA to produce malonyl-CoA may be controlled. Thus, by introducing constructs of the gene of the present invention in sense or anti-sense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased. Consequently, fatty acid synthesis in plants and seeds which depends on malonyl-CoA in the plastid may also be controlled.Type: GrantFiled: June 12, 1996Date of Patent: April 17, 2001Assignee: Board of Trustees Operating Michigan State UniversityInventors: John B. Ohlrogge, Basil Shorrosh, Keith Roesler, David Shintani, Chris Somerville
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Patent number: 5962767Abstract: An Arabidopsis acetyl-CoA carboxylase (ACCase) gene has been isolated and sequenced. The 10 kb gene encodes a 251 kD cytosolic ACCase isozyme. The nucleic acid sequence of the gene is set forth in SEQ ID No. 1 and has been accorded GenBank Accession No. L27074. The cDNA sequence and deduced amino acid sequence of the cDNA are set forth in SEQ ID Nos. 2 and 3, respectively. By controlling expression of the gene of the present invention, carboxylation of acetyl-CoA to produce malonyl-CoA may be controlled. Thus, by introducing constructs of the gene of the present invention in sense or anti-sense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased. Consequently, fatty acid synthesis and elongation in plants and seeds which depends on malonyl-CoA may also be controlled.Type: GrantFiled: January 29, 1997Date of Patent: October 5, 1999Assignee: Board of Trustees Operating Michigan State UniversityInventors: John B. Ohlrogge, Keith R. Roesler, Basil S. Shorrosh
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Patent number: 5925805Abstract: An Arabidopsis acetyl-CoA carboxylase (ACCase) gene has been isolated and sequenced. The 10-kb gene encodes a 251-kd cytosolic ACCase isozyme. The nucleic acid sequence of the gene is set forth in SEQ ID No. 1 and has been accorded GenBank Accession No. L27074. The cDNA sequence and deduced amino acid sequence of the cDNA are set forth in SEQ ID Nos. 2 and 3, respectively. By controlling expression of the gene of the present invention, carboxylation of acetyl-CoA to produce malonyl-CoA may be controlled. Thus, by introducing constructs of the gene of the present invention in sense or anti-sense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased. Consequently, fatty acid synthesis and elongation in plants and seeds which depends on malonyl-CoA may also be controlled.Type: GrantFiled: July 1, 1996Date of Patent: July 20, 1999Assignee: Board of Trustees Operating Michigan State UniversityInventors: John B. Ohlrogge, Keith R. Roesler, Basil S. Shorrosh
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Patent number: 5559220Abstract: A DNA encoding an acetyl-coenzyme A carboxylase (ACCase) from a photosynthetic organism and functional derivatives thereof which are resistant to inhibition from certain herbicides. This gene can be placed in organisms to increase their fatty acid content or to render them resistant to certain herbicides.Type: GrantFiled: April 7, 1995Date of Patent: September 24, 1996Assignee: Midwest Research InstituteInventors: Paul G. Roessler, John B. Ohlrogge
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Patent number: 5430134Abstract: The present invention relates to a process for producing lipids containing the fatty acid petroselinic acid in plants. The production of petroselinic acid is accomplished by genetically transforming plants which do not normally accumulate petroselinic acid with a gene for a .omega.12 desaturase from another species which does normally accumulate petroselinic acid.Type: GrantFiled: August 7, 1992Date of Patent: July 4, 1995Assignee: Michigan State UniversityInventors: John B. Ohlrogge, Edgar B. Cahoon, John Shanklin, Christopher R. Somerville
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Patent number: 4888282Abstract: A synthetic gene which encodes for acyl carrier protein (ACP) has been designed. Construction, cloning, and expression in E. coli of spinach ACP-I has been demonstrated. In vitro production of ACP by appropriate expression vectors carrying the synthetic gene will augment the meager supply of this protein. Analogous genes designed for expression of ACP in plants would be a useful tool for controlling fatty acid synthesis and metabolism.Type: GrantFiled: June 4, 1987Date of Patent: December 19, 1989Assignees: The United States of America as represented by the Secretary of Agriculture, Purdue UniversityInventors: Phillips D. Beremand, John B. Ohlrogge, David N. Kuhn