Patents by Inventor John B. Simpson

John B. Simpson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210345903
    Abstract: A catheter for positioning a guidewire across an occluded portion of a vessel includes an elongate catheter body, an integrated rotatable distal tip, a proximal handle region, and a catheter lumen extending through the elongate catheter body. The elongate body has a distal region configured to be bent to a set angle. The integrated rotatable distal tip includes one or more channeled flutes extending around the distal tip that are configured to be rotated in a first direction to dissect tissue and a second direction for bluntly contacting tissue. A proximal handle region includes a control for rotating the distal tip in either the first or second directions. The catheter lumen is configured to pass a guidewire.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 11, 2021
    Inventors: Himanshu N. PATEL, John B. SIMPSON
  • Patent number: 11147583
    Abstract: An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: October 19, 2021
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Ryan Radjabi
  • Patent number: 11134849
    Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: October 5, 2021
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Himanshu N. Patel, Michael Zung, Charles W. McNall, Priyanshu Gupta, Maegan K. Spencer, Christopher B. White, Dennis W. Jackson, John F. Black
  • Patent number: 11135019
    Abstract: Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: October 5, 2021
    Assignee: Avinger, Inc.
    Inventors: Maegan K. Spencer, John B. Simpson, Stephen C. Davies
  • Publication number: 20210267621
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Application
    Filed: October 20, 2020
    Publication date: September 2, 2021
    Inventors: John B. SIMPSON, Xuanmin HE, Ryan RADJABI, Richard R. NEWHAUSER
  • Patent number: 11096717
    Abstract: Versatile tissue collection devices that can provide reduced crossing profiles, fluid pressure release, and/or easy cleaning or removal. In particular, devices having tissue collection devices with multiple configurations to facilitate navigation through narrow vessel cross-sections while also providing adequate tissue storage capacity. Additionally, the devices may include detachable components that allow easy removal, cleaning, and replacement during a procedure. Furthermore, venting elements and sections may be included to relieve fluid buildup in storage reservoirs.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 24, 2021
    Assignee: Avinger, Inc.
    Inventors: Priyanshu Gupta, Christina Van, Nicholas Spinelli, John B. Simpson
  • Patent number: 11076773
    Abstract: A catheter for positioning a guidewire across an occluded portion of a vessel includes an elongate catheter body, an integrated rotatable distal tip, a proximal handle region, and a catheter lumen extending through the elongate catheter body. The elongate body has a distal region configured to be bent to a set angle. The integrated rotatable distal tip includes one or more channeled flutes extending around the distal tip that are configured to be rotated in a first direction to dissect tissue and a second direction for bluntly contacting tissue. A proximal handle region includes a control for rotating the distal tip in either the first or second directions. The catheter lumen is configured to pass a guidewire.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: August 3, 2021
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson
  • Publication number: 20210177262
    Abstract: A system for imaging a body lumen includes a controller and a display. The controller is configured to connect to a proximal end of a catheter having an optical fiber extending along the length of an elongate catheter body. The controller is further configured to rotate a distal end of the optical fiber from a location near a proximal end of the elongate catheter body, acquire optical coherence tomography (OCT) images using the optical fiber as the distal end of the optical fiber rotates, and determine a rotational lag of the distal end of the optical fiber. The display is configured to display one or more OCT images corrected for the rotational lag.
    Type: Application
    Filed: July 30, 2020
    Publication date: June 17, 2021
    Inventors: Maegan K. SPENCER, Christopher B. WHITE, Charles W. MCNALL, Dennis W. JACKSON, Michael ZUNG, Nicholas J. SPINELLI, Benjamin NGO, Evangeline LUMABAS, Kin F. CHAN, John F. BLACK, Michael H. ROSENTHAL, John B. SIMPSON
  • Patent number: 10869685
    Abstract: A rotating cutting head catheter for passage through chronic total occlusions or other refractory atherosclerotic plaque from diseased arteries is disclosed. The catheter's rotating cutting head is designed to reside safely within an outer protective sheath when not in use. The outer protective sheath contains one or more helical grooves or slots, and the cutting head contains protruding blades or projections that fit into these helical grooves or slots. Application of torque to an inner catheter or wire attached to the cutting head applies spin to the cutting head, and the force of the sheath's helical grooves or slots against the cutting head's protruding blades or projections advances the cutting head outward from the protective sheath. Once extended, the cutting head may now rotate freely. The device may use a guidewire to direct the cutting head to the desired position.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: December 22, 2020
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson
  • Patent number: 10806484
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: October 20, 2020
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Xuanmin He, Ryan Radjabi, Richard R. Newhauser
  • Publication number: 20200315654
    Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body.
    Type: Application
    Filed: November 12, 2019
    Publication date: October 8, 2020
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Anthony J. FERNANDEZ, Richard R. NEWHAUSER, Priyanshu GUPTA, Michael ZUNG, Wendy Ngo LAM, Maegan K. SPENCER, Peter Howard SMITH, Stephen C. DAVIES, Nicholas J. SPINELLI, Charles W. MCNALL, Theodore W. KETAI, Manish KANKARIA, Mark W. ASKEW, Kent C.B. STALKER
  • Patent number: 10729326
    Abstract: A system for imaging a body lumen includes a controller and a display. The controller is configured to connect to a proximal end of a catheter having an optical fiber extending along the length of an elongate catheter body. The controller is further configured to rotate a distal end of the optical fiber from a location near a proximal end of the elongate catheter body, acquire optical coherence tomography (OCT) images using the optical fiber as the distal end of the optical fiber rotates, and determine a rotational lag of the distal end of the optical fiber. The display is configured to display one or more OCT images corrected for the rotational lag.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: August 4, 2020
    Assignee: Avinger, Inc.
    Inventors: Maegan K. Spencer, Christopher B. White, Charles W. McNall, Dennis W. Jackson, Michael Zung, Nicholas J. Spinelli, Benjamin Ngo, Evangeline Lumabas, Kin F. Chan, John F. Black, Michael H. Rosenthal, John B. Simpson
  • Publication number: 20200069253
    Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.
    Type: Application
    Filed: July 9, 2019
    Publication date: March 5, 2020
    Inventors: John F. BLACK, Maegan K. SPENCER, Michael ZUNG, Charles W. MCNALL, Evangeline LUMABAS, Michael H. ROSENTHAL, John B. SIMPSON
  • Publication number: 20200069327
    Abstract: An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.
    Type: Application
    Filed: July 18, 2019
    Publication date: March 5, 2020
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Ryan RADJABI
  • Publication number: 20200060718
    Abstract: Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
    Type: Application
    Filed: July 2, 2019
    Publication date: February 27, 2020
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Charles W. McNALL, Maegan K. SPENCER, Michael ZUNG, Priyanshu GUPTA, Nicholas J. SPINELLI, Myra L. FABRO, Eduardo SUCGANG, Theodore W. KETAI
  • Patent number: 10568655
    Abstract: Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: February 25, 2020
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Himanshu N. Patel, Anthony J. Fernandez, Richard R. Newhauser
  • Patent number: 10548478
    Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 4, 2020
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Priyanshu Gupta, Michael Zung, Wendy N. Lam, Maegan K. Spencer, Peter H. Smith, Stephen C. Davies, Nicholas J. Spinelli, Charles W. McNall, Theodore W. Ketai, Manish Kankaria, Mark W. Askew, Kent C. B. Stalker
  • Patent number: 10470795
    Abstract: Atherectomy catheter devices having a C-shaped balloon opposite a cutting window out of which a rotating cutter may extend and a proximal annular balloon. The C-shaped first balloon may be used to drive the cutter against a vessel and to deploy the cutter by assisting in deflecting a nosecone (distal tip) to expose the distal-facing cutting edge of the cutter. The proximal annular balloon may be used to occlude blood flow. The device may pulled, pushed or rotated in a vessel with the balloons inflated or deflated.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 12, 2019
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Wendy Ngo Lam
  • Patent number: 10357277
    Abstract: An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: July 23, 2019
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Ryan Radjabi
  • Patent number: 10349974
    Abstract: Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: July 16, 2019
    Inventors: Himanshu N. Patel, John B. Simpson, Charles W. McNall, Maegan K. Spencer, Michael Zung, Priyanshu Gupta