Patents by Inventor John B. Simpson

John B. Simpson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11839493
    Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.
    Type: Grant
    Filed: February 22, 2022
    Date of Patent: December 12, 2023
    Assignee: AVINGER, INC.
    Inventors: John F. Black, Maegan K. Spencer, Michael Zung, Charles W. McNall, Evangeline Lumabas, Michael H. Rosenthal, John B. Simpson
  • Publication number: 20230329746
    Abstract: Described herein are atherectomy catheters, systems and methods that include a distal tip region that may be moved laterally so that its long axis is parallel with the long axis of the main catheter body axis. Displacing the distal tip region laterally out of the main catheter body axis exposes an annular blade and opens a passageway for cut tissue to enter a storage region within the catheter. The annular blade may be internally coupled to a drive shaft that rotates the blade, and thus the exposed blade edge may have the same crossing profile (OD) as the rest of the distal end region of the catheter. Also described herein are gear-driven atherectomy devices that may use a cable drive shaft to actuate the annular blade. Both push-to-cut and pull-to-cut variations are described, as are methods for cutting tissue and systems including these atherectomy catheters.
    Type: Application
    Filed: June 20, 2023
    Publication date: October 19, 2023
    Inventors: Michael H. ROSENTHAL, Michael ZUNG, Nicholas J. SPINELLI, Charles W. MCNALL, John B. SIMPSON, John F. BLACK
  • Patent number: 11717314
    Abstract: Described herein are atherectomy catheters, systems and methods that include a distal tip region that may be moved laterally so that its long axis is parallel with the long axis of the main catheter body axis. Displacing the distal tip region laterally out of the main catheter body axis exposes an annular blade and opens a passageway for cut tissue to enter a storage region within the catheter. The annular blade may be internally coupled to a drive shaft that rotates the blade, and thus the exposed blade edge may have the same crossing profile (OD) as the rest of the distal end region of the catheter. Also described herein are gear-driven atherectomy devices that may use a cable drive shaft to actuate the annular blade. Both push-to-cut and pull-to-cut variations are described, as are methods for cutting tissue and systems including these atherectomy catheters.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: August 8, 2023
    Assignee: AVINGER, INC.
    Inventors: Michael H. Rosenthal, Michael Zung, Nicholas J. Spinelli, Charles W. McNall, John B. Simpson, John F. Black
  • Publication number: 20230141567
    Abstract: Embodiments of the disclosure include apparatuses, systems, and methods for a catheter with a single element for both imaging and interventions. The catheter may have a distal tip which is positionable in a patient (e.g., in a lumen of a vessel). The distal tip may have an optical component which includes both a reflecting surface and a tapered distal end. The reflecting surface may redirect light (e.g., light received along an optical fiber of the catheter) into an imaging beam, which may be directed to a wall of the vessel. The tapered distal end may be a crossing tool used to cross an occluded or partially-occluded section of the vessel. In some embodiments, the reflecting surface and tapered distal end may be the same surface of the optical component. A low refractive index optical filler may be provided to reduce image artifacts at the imaging interface with the patient's fluid and tissue.
    Type: Application
    Filed: April 22, 2021
    Publication date: May 11, 2023
    Inventors: John B. Simpson, Kin Foong Chan, Wendy Lam, Sergio Salinas, Evangeline Lumabas
  • Publication number: 20220361743
    Abstract: Imaging apparatus, atherectomy devices, systems, and methods of operation thereof are disclosed. The imaging apparatus further comprises one or more light transmittable windows defined along the dividing layer and a catheter outlet port defined along a ventral side of the catheter body. The catheter outlet port allows the guidewire to advance out of the second catheter lumen and the catheter outlet port is aligned with at least one of the light transmittable windows such that the guidewire is within a field of view of the imaging component when the guidewire extends partially though the catheter outlet port. The atherectomy device can comprise a tubular housing and an inflatable balloon coupled to an exterior side of the tubular housing. The tubular housing includes a cutting window and a rotatable cutter configured to debulk the atherosclerotic material extending into the cutting window.
    Type: Application
    Filed: September 25, 2020
    Publication date: November 17, 2022
    Inventors: Kin F Chan, John B. Simpson
  • Publication number: 20220273337
    Abstract: Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
    Type: Application
    Filed: May 20, 2022
    Publication date: September 1, 2022
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Charles W. McNALL, Maegan K. SPENCER, Michael ZUNG, Priyanshu GUPTA, Nicholas J. SPINELLI, Myra L. FABRO, Eduardo SUCGANG, Theodore W. KETAI
  • Publication number: 20220240860
    Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.
    Type: Application
    Filed: February 22, 2022
    Publication date: August 4, 2022
    Inventors: John F. BLACK, Maegan K. SPENCER, Michael ZUNG, Charles W. MCNALL, Evangeline LUMABAS, Michael H. ROSENTHAL, John B. SIMPSON
  • Patent number: 11382653
    Abstract: Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: July 12, 2022
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Charles W. McNall, Maegan K. Spencer, Michael Zung, Priyanshu Gupta, Nicholas J. Spinelli, Myra L. Fabro, Eduardo Sucgang, Theodore W. Ketai
  • Publication number: 20220168011
    Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body.
    Type: Application
    Filed: February 17, 2022
    Publication date: June 2, 2022
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Anthony J. FERNANDEZ, Richard R. NEWHAUSER, Priyanshu GUPTA, Michael ZUNG, Wendy Ngo LAM, Maegan K. SPENCER, Peter Howard SMITH, Stephen C. DAVIES, Nicholas J. SPINELLI, Charles W. MCNALL, Theodore W. KETAI, Manish KANKARIA, Mark W. ASKEW, Kent C.B. STALKER
  • Publication number: 20220125525
    Abstract: Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.
    Type: Application
    Filed: October 4, 2021
    Publication date: April 28, 2022
    Inventors: Maegan K. SPENCER, John B. SIMPSON, Stephen C. DAVIES
  • Publication number: 20220095926
    Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.
    Type: Application
    Filed: October 4, 2021
    Publication date: March 31, 2022
    Inventors: John B. SIMPSON, Himanshu N. PATEL, Michael ZUNG, Charles W. MCNALL, Priyanshu GUPTA, Maegan K. SPENCER, Christopher B. WHITE, Dennis W. JACKSON, John F. BLACK
  • Patent number: 11284916
    Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: March 29, 2022
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Anthony J. Fernandez, Richard R. Newhauser, Priyanshu Gupta, Michael Zung, Wendy Ngo Lam, Maegan K. Spencer, Peter Howard Smith, Stephen C. Davies, Nicholas J. Spinelli, Charles W. McNall, Theodore W. Ketai, Manish Kankaria, Mark W. Askew, Kent C. B. Stalker
  • Patent number: 11284839
    Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: March 29, 2022
    Assignee: Avinger, Inc.
    Inventors: John F. Black, Maegan K. Spencer, Michael Zung, Charles W. McNall, Evangeline Lumabas, Michael H. Rosenthal, John B. Simpson
  • Publication number: 20220079617
    Abstract: Versatile tissue collection devices that can provide reduced crossing profiles, fluid pressure release, and/or easy cleaning or removal. In particular, devices having tissue collection devices with multiple configurations to facilitate navigation through narrow vessel cross-sections while also providing adequate tissue storage capacity. Additionally, the devices may include detachable components that allow easy removal, cleaning, and replacement during a procedure. Furthermore, venting elements and sections may be included to relieve fluid buildup in storage reservoirs.
    Type: Application
    Filed: August 23, 2021
    Publication date: March 17, 2022
    Inventors: Priyanshu GUPTA, Christina VAN, Nicholas J. SPINELLI, John B. SIMPSON
  • Publication number: 20220039828
    Abstract: An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.
    Type: Application
    Filed: October 12, 2021
    Publication date: February 10, 2022
    Inventors: Himanshu N. PATEL, John B. SIMPSON, Ryan RADJABI
  • Publication number: 20210345903
    Abstract: A catheter for positioning a guidewire across an occluded portion of a vessel includes an elongate catheter body, an integrated rotatable distal tip, a proximal handle region, and a catheter lumen extending through the elongate catheter body. The elongate body has a distal region configured to be bent to a set angle. The integrated rotatable distal tip includes one or more channeled flutes extending around the distal tip that are configured to be rotated in a first direction to dissect tissue and a second direction for bluntly contacting tissue. A proximal handle region includes a control for rotating the distal tip in either the first or second directions. The catheter lumen is configured to pass a guidewire.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 11, 2021
    Inventors: Himanshu N. PATEL, John B. SIMPSON
  • Patent number: 11147583
    Abstract: An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: October 19, 2021
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, John B. Simpson, Ryan Radjabi
  • Patent number: 11134849
    Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: October 5, 2021
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Himanshu N. Patel, Michael Zung, Charles W. McNall, Priyanshu Gupta, Maegan K. Spencer, Christopher B. White, Dennis W. Jackson, John F. Black
  • Patent number: 11135019
    Abstract: Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: October 5, 2021
    Assignee: Avinger, Inc.
    Inventors: Maegan K. Spencer, John B. Simpson, Stephen C. Davies
  • Publication number: 20210267621
    Abstract: Described herein is a system and method for identifying elastic lamina during interventional procedures, such as atherectomy. Such identification can be used to avoid trauma to the external elastic lamina during the procedure.
    Type: Application
    Filed: October 20, 2020
    Publication date: September 2, 2021
    Inventors: John B. SIMPSON, Xuanmin HE, Ryan RADJABI, Richard R. NEWHAUSER