Patents by Inventor John B. Sullivan

John B. Sullivan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8048414
    Abstract: F(ab) fragments are isolated from an antibody containing source by contacting the antibody containing source with a papain-polyacrylamide matrix to produce F(ab) and F(c) fragments which are then passed through an antigen-polyacrylamide gel capable of attracting the F(ab) fragments. F(ab)2 fragments are obtained by contacting the antibody containing source with a pepsin-polyacrylamide matrix to produce F(ab)2 and F(c) fragments which are then passed through an antigen-polyacrylamide gel capable of attracting the F(ab)2 fragments. IgG antibodies are obtained by passing an antibody containing source through an antigen-polyacrylamide gel. These processes can be used to purify a wide variety of antibodies which can be used as therapeutic agents and as diagnostic agents. Antivenins produced by these processes have substantially reduced foreign protein levels and hence are less likely to produce immunogenic reactions.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: November 1, 2011
    Assignee: BTG International Inc.
    Inventors: John B. Sullivan, Findlay E. Russell
  • Patent number: 4849352
    Abstract: F(ab) fragments are isolated from an antibody containing source by contacting the antibody containing source with a papain-polyacrylamide matrix to produce F(ab) and F(c) fragments which are then passed through an antigen-polyacrylamide gel capable of attracting the F(ab) fragments. F(ab).sub.2 fragments are obtained by contacting the antibody containing source with a pepsin-polyacrylamide matrix to produce F(ab).sub.2 and F(c) fragments which are then passed through an antigen-polyacrylamide gel capable of attracting the F(ab).sub.2 fragments. IgG antibodies are obtained by passing an antibody containing source through an antigen-polyacrylamide gel. These processes can be used to purifiy a wide variety of antibodies which can be used as therapeutic agents and as diagnostic agents. Antivenins produced by these processes have substantially reduced foreign protein levels and hence are less likely to produce immunogenic reactions.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: July 18, 1989
    Inventors: John B. Sullivan, Findlay E. Russell
  • Patent number: 4213252
    Abstract: The terrain objects within the data base for an aircraft flight simulation system are formed by polygon faces and include certain objects formed by repetitive patterns of equally spaced identical polygon faces. More specifically, objects such as runway markings, which are a series of elongated narrow rectangles equally spaced along the length of the runway. The image data is arranged in a particular format including instruction words for identifying the type of data in the data words following each instruction word, and for controlling the flow of data through the image processor. The image data formatted and processed includes:Initialization vectors (Vo), defining the position of landmark points (i.e., the first vertex of the initial polygon of each series of faces).Delta data (shape data), defining the position of other points, (i.e., the remaining vertices of each initial face) with respect to the initial point therefor.
    Type: Grant
    Filed: May 8, 1978
    Date of Patent: July 22, 1980
    Assignee: The Singer Company
    Inventors: John B. Sullivan, David R. Marsh
  • Patent number: 4179823
    Abstract: The visual system within an aircraft flight simulation system receives flight data from a flight simulation computer, and terrain data from a gaming area data base. A computer within the visual system organizes this image data in a buffer memory according to a particular format, and forwards the image data to an image processor. The following types of data are formatted and processed:Position vectors, defining the changing position of the aircraft with respect to the origin of the terrain coordinate system.Rotational data, defining the changing attitude of the aircraft with respect to the terrain coordinate system.Initialization vectors, defining the position of the landmark points within the terrain coordinate system. The landmark points are translated into the aircraft coordinate system to form translated vectors.Delta data, defining the position of other points, lines, and faces with respect to the landmark points.CIF data, defining color, intensity, defocus, etc.
    Type: Grant
    Filed: January 13, 1978
    Date of Patent: December 25, 1979
    Assignee: The Singer Company
    Inventors: John B. Sullivan, David R. Marsh, Raymond C. Osofsky, Steven R. Bryan, William D. Fahey, David E. Manners