Abstract: A sterile pharmaceutically acceptable aqueous solution, which solution is provided in a sealed container and comprises: a pharmaceutically acceptable aqueous solvent; viral particles or a physiologically active polypeptide; an excipient selected from a polyethyleneimine; a compound of formula (I) or a physiologically acceptable salt or ester thereof; or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and optionally, one or more sugars.

Abstract: The invention is directed to methods, reagents and kits for detecting incident HIV-1 infection.

Abstract: A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating said viral particles.

Abstract: A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating said viral particles.

Abstract: A sterile pharmaceutically acceptable aqueous solution, which solution is provided in a sealed container and comprises: a pharmaceutically acceptable aqueous solvent; viral particles or a physiologically active polypeptide; an excipient selected from a polyethyleneimine; a compound of formula (I) or a physiologically acceptable salt or ester thereof; or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and optionally, one or more sugars.

Abstract: A sterile pharmaceutically acceptable aqueous solution, which solution is provided in a sealed container and comprises: a pharmaceutically acceptable aqueous solvent; viral particles or a physiologically active polypeptide; an excipient selected from a polyethyleneimine; a compound of formula (I) or a physiologically acceptable salt or ester thereof; or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and optionally, one or more sugars.

Abstract: A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating said viral particles.

Abstract: Techniques for controlling a light source in a wavelength division multiplexed passive optical network (WDM-PON) are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for controlling a light source in a wavelength division multiplexed passive optical network (WDM-PON). The apparatus may include a digital signal processing device configured to output a pilot tone signal. The apparatus may also include an amplifier configured to modulate a modulation current and the pilot tone signal, and output an amplitude modulated signal. The apparatus may further include a capacitor configured to AC couple the amplitude modulated signal to a bias current applied to a light source; and a monitoring photodiode configured to detect an output optical signal of the light source and transmit the detected output optical signal to the digital signal processing device to control the output optical signal of the light source.

Abstract: A Wavelength Division Multiplexed Passive Optical Network (WDM-PON) includes an Optical Line Terminal (OLT) including a first Arrayed Waveguide Grating (AWG) MUX/DEMUX, and a remote node including a second AWG MUX/DEMUX. Each AWG MUX/DEMUX has at least two input ports for receiving a respective wavelength division multiplexed optical signal, and a plurality of output ports. Each output port of the Optical Line Terminal AWG MUX/DEMUX is coupled to a respective transceiver of the OLT. Each output port of the remote node AWG MUX/DEMUX is coupled to a respective PON having at least one optical network terminal (ONT). Respective first and second optical paths are coupled between corresponding input ports of the first and second AWG MUX/DEMUXs. Means are provided for sourcing seed light of the WDM-PON into a selected one the first and second optical paths.

Abstract: Described is a method for controlling the wavelength of a laser in a wavelength division multiplexed (WDM) system. The method includes generating broadband light having a dithered optical power and a wavelength spectrum that includes a plurality of WDM wavelengths. The broadband light is spectrally filtered to generate a spectrally-sliced optical signal having a wavelength spectrum that includes one of the WDM wavelengths. The spectrally-sliced optical signal is injected into a laser and a dithered optical power of the laser is determined. A parameter of the laser is controlled in response to the determination of the dithered optical power to thereby align a wavelength of the laser to the wavelength spectrum of the spectrally-sliced optical signal.

Abstract: In a method of controlling an injection-seeded laser, a response of the laser is sampled at a plurality of different laser current values. A threshold current and a slope efficiency of the sampled response are then estimated, and a bias current and a modulation current calculated based on the estimated threshold current and a slope efficiency.

Abstract: Techniques for controlling a light source in a wavelength division multiplexed passive optical network (WDM-PON) are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for controlling a light source in a wavelength division multiplexed passive optical network (WDM-PON). The apparatus may include a digital signal processing device configured to output a pilot tone signal. The apparatus may also include an amplifier configured to modulate a modulation current and the pilot tone signal, and output an amplitude modulated signal. The apparatus may further include a capacitor configured to AC couple the amplitude modulated signal to a bias current applied to a light source; and a monitoring photodiode configured to detect an output optical signal of the light source and transmit the detected output optical signal to the digital signal processing device to control the output optical signal of the light source.

Abstract: Techniques for implementing a dual array waveguide filter for a wavelength division multiplexed passive optical network (WDM-PON) are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for implementing a dual waveguide filter for a wavelength division multiplexed passive optical network (WDM-PON). The apparatus may include a first light source configured to output a first broadband optical signal for generating a downstream optical signal. The apparatus may also include a second light source configured to output a second broadband optical signal for generating an upstream optical signal. The apparatus may further include a dual array waveguide filter having a first optical transmission path and a second optical transmission path, wherein the first optical transmission path is configured to spectrally slice the first broadband optical signal and the second optical transmission path is configured to demultiplex the upstream optical signal.

Abstract: Multiple techniques are disclosed for hardening a self-clocking circuit against glitches. Glitch filters are placed in some portions of a digital design. In some embodiments the glitch filter is dynamically tunable. In one embodiment the inputs are locked out by the outputs. Methods for evaluating code symbols are presented, as is a circuit for differential signaling.

Abstract: Described is a method for controlling the wavelength of a laser in a wavelength division multiplexed (WDM) system. The method includes generating broadband light having a dithered optical power and a wavelength spectrum that includes a plurality of WDM wavelengths. The broadband light is spectrally filtered to generate a spectrally-sliced optical signal having a wavelength spectrum that includes one of the WDM wavelengths. The spectrally-sliced optical signal is injected into a laser and a dithered optical power of the laser is determined. A parameter of the laser is controlled in response to the determination of the dithered optical power to thereby align a wavelength of the laser to the wavelength spectrum of the spectrally-sliced optical signal.

Abstract: A Wavelength Division Multiplexed Passive Optical Network (WDM-PON) includes an Optical Line Terminal (OLT) including a first Arrayed Waveguide Grating (AWG) MUX/DEMUX, and a remote node including a second AWG MUX/DEMUX. Each AWG MUX/DEMUX has at least two input ports for receiving a respective wavelength division multiplexed optical signal, and a plurality of output ports. Each output port of the Optical Line Terminal AWG MUX/DEMUX is coupled to a respective transceiver of the OLT. Each output port of the remote node AWG MUX/DEMUX is coupled to a respective PON having at least one optical network terminal (ONT). Respective first and second optical paths are coupled between corresponding input ports of the first and second AWG MUX/DEMUXs. Means are provided for sourcing seed light of the WDM-PON into a selected one the first and second optical paths.

Abstract: The present invention enables asynchronous circuits to be tested in the same manner and using the same equipment and test strategies as with synchronous circuits. The feedback path of an asynchronous element, for example a Muller C element, includes a test structure which may be invoked for the purpose of providing the means for synchronous testing. When configured for testing, the test structure provides a clocked latching and selecting function which, by virtue of breaking the feedback path of the self-timing device, prevents the device being tested from switching states until desired. When the element is not in test mode, the test structure is configured to pass through the data that normally flows through the feedback path unchanged. The result is an ability to test an asynchronous device or subsystem of a device in the same manner as and/or intermixed with a synchronous device.