Abstract: A moving bed assembly includes a bed frame supported over a base frame by pivoting swing arms and driven in a controlled motion by a motor-driven shaft and drive arms. A protective barrier is mounted to the base frame to restrict access to moving components, and an electrical interlock disables the motor when the barrier is removed or displaced. The assembly also includes a crush detection system positioned along a perimeter of the bed frame or base frame. The crush detection system uses a compressible sensor tube containing a light emitter and a light sensor arranged to detect a transmitted light signal, with compression disrupting the signal and causing a controller to disable the motor until the obstruction is cleared and the system reset. The features provide controlled bed motion with enhanced safety.

Abstract: A moving bed assembly includes a base frame supporting a bed frame via a plurality of pairs of swing arms. A drive motor mounted on the base frame drives the bed frame through a continuous motion cycle through a drive shaft. Cranks are mounted at opposite ends of the drive shaft and connected to respective swing arms through respective drive arms. A shaft brake engages the drive shaft to prevent perceptible surges as the bed frame transitions through opposite extremes of the motion cycle.

Abstract: An immune classification tool useful for determining survival outcomes in cancer patients based on the abundance in gene expression of CD3E, ZAP70 and IRF4 in a cancer tissue sample. The immune classification tool is able to stratify cancer patients, including HPV+HNSCC, HPV?HNSCC and cervical cancer patients, into the three immune groups (immune rich, immune desert, and mixed) that are strongly associated with disease-free survival.

Abstract: An orthopedic implant with an inferior portion having a tibia contact surface configured to extend over a tibia; a superior portion opposite to the inferior portion having a tendon contact surface configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the curved surface of the first portion is engaged with the tibia; a fixation mechanism adapted to attach the orthopedic implant to the tibia; and an adjustment mechanism adapted to change a distance between the tendon contact surface and the tibia contact surface. The invention also includes a method for repositioning a patellar tendon of a patient.

Abstract: A moving bed assembly includes a base frame supporting a bed frame via a plurality of pairs of swing arms. A drive motor mounted on the base frame drives the bed frame through a continuous motion cycle through a drive shaft. Cranks are mounted at opposite ends of the drive shaft and connected to respective swing arms through respective drive arms. A shaft brake engages the drive shaft to prevent perceptible surges as the bed frame transitions through opposite extremes of the motion cycle.

Abstract: Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.

Abstract: Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.

Abstract: An orthopedic implant with an inferior portion having a tibia contact surface configured to extend over a tibia; a superior portion opposite to the inferior portion having a tendon contact surface configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the curved surface of the first portion is engaged with the tibia; and a fixation mechanism adapted to attach the orthopedic implant to the tibia, the orthopedic implant being further configured to change shape from a first configuration to a second configuration in response to a load applied between the tendon contact surface and the tibia contact surface. The invention also addresses corresponding methods.

Abstract: An orthopedic implant with an inferior portion having a tibia contact surface configured to extend over a tibia; a superior portion opposite to the inferior portion having a tendon contact surface configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the curved surface of the first portion is engaged with the tibia; and a fixation mechanism adapted to attach the orthopedic implant to the tibia, the orthopedic implant being further configured to change shape from a first configuration to a second configuration in response to a load applied between the tendon contact surface and the tibia contact surface. The invention also addresses corresponding methods.

Abstract: A flow management and separation system for a wellbore having a horizontal section, vertical section and intermediate build section, a production tubing, and an annulus surrounding the production tubing, is combined with a primary vertical lift device disposed in the intermediate build section or a heel segment of the horizontal section. The fluid flow management system may be located adjacent to and downhole from the primary vertical lift device. The system includes an intake to an intake passage, to receive produced fluids from the reservoir; a wavebreaker for calming produced fluid flow; a fluidseeker having a rotatable inlet extension having a weighted keel and an internal bypass passage in fluid communication with the intake flow passage; and a separator for separating gas and liquid phases uphole from the fluidseeker.

Abstract: An orthopedic implant with an inferior portion having a tibia contact surface configured to extend over a tibia; a superior portion opposite to the inferior portion having a tendon contact surface configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the curved surface of the first portion is engaged with the tibia; a fixation mechanism adapted to attach the orthopedic implant to the tibia; and an adjustment mechanism adapted to change a distance between the tendon contact surface and the tibia contact surface. The invention also includes a method for repositioning a patellar tendon of a patient.

Abstract: Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.

Abstract: Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.

Abstract: An orthopedic implant with an inferior portion having a tibia contact surface configured to extend over a tibia; a superior portion opposite to the inferior portion having a tendon contact surface configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the curved surface of the first portion is engaged with the tibia; and a fixation mechanism adapted to attach the orthopedic implant to the tibia, the orthopedic implant being further configured to change shape from a first configuration to a second configuration in response to a load applied between the tendon contact surface and the tibia contact surface. The invention also addresses corresponding methods.

Abstract: An orthopedic implant system including an orthopedic implant with an inferior portion having a surface configured to extend over a top surface of a tibia; a superior portion opposite to the inferior portion and configured to change a position of a patellar tendon by lifting or tilting the patellar tendon when the surface of the inferior portion is engaged with the tibia; a first lateral side disposed between the inferior portion and the superior portion; and a second lateral side disposed between the inferior portion and the superior portion opposite to the first lateral side; and a fixation system to attach the orthopedic implant to the tibia. The invention also includes corresponding methods.

Abstract: A flow management and separation system for a wellbore having a horizontal section, vertical section and intermediate build section, a production tubing, and an annulus surrounding the production tubing, is combined with a primary vertical lift device disposed in the intermediate build section or a heel segment of the horizontal section. The fluid flow management system may be located adjacent to and downhole from the primary vertical lift device. The system includes an intake to an intake passage, to receive produced fluids from the reservoir; a wavebreaker for calming produced fluid flow; a fluidseeker having a rotatable inlet extension having a weighted keel and an internal bypass passage in fluid communication with the intake flow passage; and a separator for separating gas and liquid phases uphole from the fluidseeker.

Abstract: A pump system and method for producing fluids from a reservoir using a wellbore having a vertical section with a casing defining a wellbore annulus, a horizontal section in fluid communication with the wellbore annulus, and a production tubing having a vertical section, a horizontal section and a toe end, the production tubing defining a continuous flow path from the toe end to the vertical section, the system comprising a plurality of horizontal pump assemblies operating in parallel in the production tubing horizontal section. Each horizontal pump assembly includes a pump having an intake exposed to the reservoir and an outlet in the continuous flow path, and a fluidseeker which has an inner conduit forming the continuous flow path and defining an inlet chamber, and including an axially rotatable inlet extension disposed in the inlet chamber. The inlet extension has a weighted keel defining inlet ports which are in fluid communication with the inlet chamber and a fluid inlet for the pump.

Abstract: A ticket dispenser comprising a housing body, a lockable housing door configured to close an opening in the housing body, a ticket dispensing aperture, a lockable security cover configured to prevent the removal of tickets through the aperture, and a lock assembly, wherein the lock assembly is configured to lock the housing door and security cover when in a first orientation, wherein the lock assembly is configured to lock the housing door and not to lock the security cover when in a second orientation, and wherein the lock assembly is configured not to lock the housing door or the security cover when in a third orientation.

Abstract: An apparatus that senses temperature from a digital infrared sensor is described. A digital signal representing a temperature without conversion from analog is transmitted from the digital infrared sensor received by a microprocessor and converted to body core temperature by the microprocessor.

Abstract: Spinal curvature modulation systems, methods and related devices and instrumentation are disclosed, which include a flexible tether, a tether tensioning unit and bone anchors for the flexible tether that allow the tether to be secured across multiple vertebrae in a region of treatment. When the flexible tether is attached to multiple vertebrae, it can be used to correct spinal deformities. Tension in the flexible tether is adjustable transcutaneously without invasive surgical procedures by use of remotely driven actuators, such as a magnet-driven motor, or by a small tool insertable through a small incision. Disclosed systems and methods thus allow for multiple adjustments of tether tension, and spinal curvature, over time without repeated, highly invasive, spinal surgeries.