Abstract: Provided are methods for treating Alzheimer's disease in a human subject in need thereof comprising administration of multiple doses of an anti-beta-amyloid antibody (e.g., aducanumab) to the subject.

Abstract: In one embodiment, a first computing device receives a write request and data from a second computing device; iteratively attempts to write the data until a copy of the data is successfully written to each and every storage node belonging to a storage volume; and transmits a volume identifier of the storage volume and a data identifier assigned to the data to the second computing device. In one embodiment, a first computing device receives a read request and a volume identifier and a data identifier from a second computing device; accesses a cache to select the storage volume identified by the volume identifier; iteratively attempts to read data identified by the data identifier until a copy of the data is successfully read from a storage node belonging to the selected storage volume; and transmits the copy of the data to the second computing device.

Abstract: In one embodiment, a first computing device receives a write request and data from a second computing device; iteratively attempts to write the data until a copy of the data is successfully written to each and every storage node belonging to a storage volume; and transmits a volume identifier of the storage volume and a data identifier assigned to the data to the second computing device. In one embodiment, a first computing device receives a read request and a volume identifier and a data identifier from a second computing device; accesses a cache to select the storage volume identified by the volume identifier; iteratively attempts to read data identified by the data identifier until a copy of the data is successfully read from a storage node belonging to the selected storage volume; and transmits the copy of the data to the second computing device.

Abstract: In one embodiment, a first computing device receives a write request and data from a second computing device; iteratively attempts to write the data until a copy of the data is successfully written to each and every storage node belonging to a storage volume; and transmits a volume identifier of the storage volume and a data identifier assigned to the data to the second computing device. In one embodiment, a first computing device receives a read request and a volume identifier and a data identifier from a second computing device; accesses a cache to select the storage volume identified by the volume identifier; iteratively attempts to read data identified by the data identifier until a copy of the data is successfully read from a storage node belonging to the selected storage volume; and transmits the copy of the data to the second computing device.

Abstract: In one embodiment, a first computing device receives a write request and data from a second computing device; iteratively attempts to write the data until a copy of the data is successfully written to each and every storage node belonging to a storage volume; and transmits a volume identifier of the storage volume and a data identifier assigned to the data to the second computing device. In one embodiment, a first computing device receives a read request and a volume identifier and a data identifier from a second computing device; accesses a cache to select the storage volume identified by the volume identifier; iteratively attempts to read data identified by the data identifier until a copy of the data is successfully read from a storage node belonging to the selected storage volume; and transmits the copy of the data to the second computing device.

Abstract: A wiskar for sharpening cutting teeth of a chain provided on a chain bar of a chain saw. A housing is removably attached to the chain bar and includes a recess to receive the wiskar therein. The wiskar includes a first member configured to be operationally engaged by the recess of the housing; and a second member configured to frictionally engage a bottom surface of the cutting teeth. The second member includes a body portion intermediate the opposing ends, wherein opposing ends of the second member each have at least one lobe defined therein. Abrasives are uniformly impregnated throughout the first and second member to sharpen the bottom surface of the cutting teeth. At least the second member is manufactured from a pliable material that erodes due to friction caused by the cutting teeth engaging the lobes of the second member.

Abstract: A wiskar for sharpening cutting teeth of a chain provided on a chain bar of a chain saw. A housing is removably attached to the chain bar and includes a recess to receive the wiskar therein. The wiskar includes a first member configured to be operationally engaged by the recess of the housing; and a second member configured to frictionally engage a bottom surface of the cutting teeth. The second member includes a body portion intermediate the opposing ends, wherein opposing ends of the second member each have at least one lobe defined therein. Abrasives are uniformly impregnated throughout the first and second member to sharpen the bottom surface of the cutting teeth. At least the second member is manufactured from a pliable material that erodes due to friction caused by the cutting teeth engaging the lobes of the second member.