Abstract: A sterile, ready-to-use, flowable haemostatic composition comprises a soluble haemostatic agent comprising a plurality of carriers and a plurality of fibrinogen binding peptides immobilised to the carrier; a biocompatible liquid; and particles of biocompatible cross-linked polysaccharide suitable for use in haemostasis and which are insoluble in the biocompatible liquid. Such compositions may be used for the control of bleeding, especially in surgical procedures.

Abstract: Haemostatic materials are described, particularly haemostatic materials comprising an oxidised cellulose substrate covalently immobilised to a plurality of fibrinogen-binding peptides. Methods are described for covalently attaching fibrinogen binding peptides to oxidised cellulose substrates ad other substrates that have carboxyl groups on their surface.

Abstract: A haemostatic device comprises a surgical fastener and a plurality of fibrinogen binding peptides immobilised to the fastener. The surgical fastener may be a suture. The device may prevent or reduce bleeding, such as suture hole bleeding, during surgical procedures.