Abstract: A security bolt includes a unitary case having a front surface, a rear surface and being formed to define a substantially enclosed, elongate passageway. A strike has a front surface, a rear surface and is formed to define a strike passageway being alignable with the elongate passageway. An elongate bolt is reciprocally engaged in the elongate passageway between a retracted position and an extended position in which a free end of the bolt is received in the strike passageway. At least one of the case and the strike is configured so that opposed edges engage each other at the rear surface along a line obscured by the respective front surface.

Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for treating human papilloma virus (HPV) infection. The dsRNA comprises an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of an HPV Target gene selected from among HPV E1, HPV E6 and the human E6AP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HPV infection and the expression of the E6AP gene using the pharmaceutical composition; and methods for inhibiting the expression of the HPV Target genes in a cell.

Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for treating human papilloma virus (HPV) infection. The dsRNA comprises an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of an HPV Target gene selected from the human E6AP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HPV infection and the expression of the E6AP gene using the pharmaceutical composition; and methods for inhibiting the expression of the HPV Target genes in a cell.

Abstract: A system and method for detecting a surgical implement retained within a surgically exposed human body cavity, includes a tag adapted to be attached to a surgical implement insertable within a human body cavity, including a means for receiving an electromagnetic signal and converting it into electric signal; and a means to impress said electric signal on the internal human (or an animal) body where said medical product is used; and means to transmit said electromagnetic signal; and a detecting means including reception means for receiving the electric signal from the body and a detector means connected to the reception means for detecting the electric signal. The envelope of the induced RF wave is demodulated, thus allowing the voltage at the output to vary at a significantly lower frequency. In the event such pulses are sensed, a sensory alert is actuated.

Abstract: The container handling device may include features useful for supporting a container (e.g., an open top rectangular bin) while the container is being filled, and supporting the container when tipping the container to empty contents of the container. The container handling device includes features that improve safe handling of the container when emptying. The container handling device also includes features that provide improved assembly and disassembly of various features for the purposes of, for example, manufacturing, shipping, replacing parts, and conducting maintenance.

Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for treating human papilloma virus (HPV) infection. The dsRNA comprises an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of an HPV Target gene selected from among HPV E1, HPV E6 and the human E6AP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HPV infection and the expression of the E6AP gene using the pharmaceutical composition; and methods for inhibiting the expression of the HPV Target genes in a cell.

Abstract: By virtue of the present invention, there is provided methods and compositions for interfering with the proliferation of cells infected and/or transformed by papillomaviruses. The processes and compositions of this invention may be used to treat any mammal, including humans. According to this invention, mammals are treated by the pharmaceutically acceptable administration of an E2 peptidomimetic to reduce the symptoms of the specific papillomavirus-associated disease, or to prevent their recurrence.

Abstract: The container handling device may include features useful for supporting a container (e.g., an open top rectangular bin) while the container is being filled, and supporting the container when tipping the container to empty contents of the container. The container handling device includes features that improve safe handling of the container when emptying. The container handling device also includes features that provide improved assembly and disassembly of various features for the purposes of, for example, manufacturing, shipping, replacing parts, and conducting maintenance.

Abstract: An apparatus for scarfing a fibrous web includes a rotatable scarfing roll with vacuum ports and an air moving source in fluid communication with the vacuum ports. The rotatable scarfing roll has a core member which includes a plurality of scarfing elements connected thereto and vacuum ports located therein. A method for scarfing a fibrous web includes providing a rotatable scarfing roll with vacuum ports and reducing scarfing wind by applying vacuum to the vacuum ports. A method for producing absorbent articles includes providing a fibrous web, contacting the fibrous web with a rotatable scarfing roll with vacuum ports to remove a portion of the fibrous web, applying vacuum to the vacuum ports to reduce scarfing wind, and producing an absorbent article with the fibrous web.

Abstract: The invention relates to an apparatus and method of making a solid film. Viscous material (163) is input into a nip between a patterned roller (165) and a belt (167). The nip between the patterned roller (165) and belt (167) is facilitated by a compliant roller (169). Accordingly, a film may be produced that has discrete optical elements and a smooth backside.

Abstract: A method of forming an element of an imaging device and the element are disclosed. The method includes providing a first layer and a second layer. The method also includes extruding the first layer with the second layer, where the second layer has a melt flow that is at least 10% greater than a melt flow of the second layer. Moreover, the method includes forming a plurality of optical elements over a surface of the second layer.

Abstract: A method of forming an element of an imaging device includes providing a first layer and a second layer. The method also includes extruding the first layer with the second layer, where the first layer has a melt viscosity at a point of extrusion that is greater than a melt viscosity at the point of extrusion of the second layer. Moreover, the method includes forming a plurality of optical elements over a surface of the second layer.

Abstract: The invention relates to an apparatus and method of making a solid film. Viscous material (163) is input into a nip between a patterned roller (165) and a belt (167). The nip between the patterned roller (165) and belt (167) is facilitated by a compliant roller (169). Accordingly, a film may be produced that has discrete optical elements and a smooth backside.

Abstract: An apparatus produces a patterned material which comprises an external land die (120) for extruding a material. A patterned roller (140) is in close proximity to the external land die.

Abstract: The invention relates to a base comprising a closed cell foam core sheet having a closed cell foam layer with a density gradient between the center of the core and the surfaces of the core. The invention also relates to a method of making such a base by adding a first concentration of a first blowing agent to a first polymer to form a first mixture, adding a second concentration of a second blowing agent to a second polymer to form a second mixture, and extruding the mixtures to form the closed cell foam core sheet. The invention also relates to a method of making such a closed cell foam core sheet base comprising the steps of adding a blowing agent to a polymer to form a mixture, melting the mixture, extruding the mixture from a die, and rapidly quenching the mixture against a high heat transfer surface.

Abstract: By virtue of the present invention, there is provided methods and compositions for interfering with the proliferation of cells infected and/or transformed by papillomaviruses. The processes and compositions of this invention may be used to treat any mammal, including humans. According to this invention, mammals are treated by the pharmaceutically acceptable administration of an E2 peptidomimetic to reduce the symptoms of the specific papillomavirus-associated disease, or to prevent their recurrence.

Abstract: The invention provides methods and compositions for screening and identifying of peptide aptamers that can modulate a cell phenotype and further, can be used for the treatment of a disease involving a misregulated cell phenotype, such as, for example, a cancer. The invention encompasses methods and compositions for producing cyclic peptide aptamers, including peptide aptamers comprising a conotoxin sequence, having improved stability and bioactivity. The invention also provides methods and compositions for improved gene delivery and expression of a peptide aptamer in cell.

Abstract: A method for forming an abrasion resistant sheet which comprises forming a web of cellulosic fibers on a papermaking machine and applying a slurry including an encapsulated abrasion-resistant grit to the upper surface of the web on the papermaking machine.

Abstract: By virtue of the present invention, there is provided methods and compositions for interfering with the proliferation of cells infected and/or transformed by papillomaviruses. The processes and compositions of this invention may be used to treat any mammal, including humans. According to this invention, mammals are treated by the pharmaceutically acceptable administration of an E2 peptidomimetic to reduce the symptoms of the specific papillomavirus-associated disease, or to prevent their recurrence.