Abstract: A conveyor dryer for curing ink on a substrate is provided. The dryer comprises a dryer body, a housing functionally coupled to the dryer body, the housing and dryer body defining a heat zone, a heating element functionally disposed within the heat zone and configured to provide thermal energy, an infeed extension functionally coupled to the dryer body, such that the infeed extension extends substantially horizontally from the dryer body, a conveyor belt functionally coupled to the infeed extension, the conveyor belt being configured to transition from the infeed extension into the heat zone, and a sensor functionally coupled to the infeed extension and configured to sense the substrate on the conveyor belt, wherein under the condition that the substrate is placed on the conveyor belt, the sensor senses the substrate and results in the dryer transitioning from a standby state to an operational state.

Abstract: The present invention generally provides apparatus and methods of operating a pumping system. The pump control apparatus includes a first sensor for measuring strain on a structure of the well pumping system and a second sensor for measuring a position of the structure. The apparatus also has a controller configured to control the well unit by receiving output signals from the first and second sensors and generating control signals according to a motor control sequence. This controller may be mounted to the structure of the pumping system to measure the strain experienced by the structure. The control signals may be transmitted to a motor control panel using a cable-less communications system. Preferably, the first sensor, the second sensor, and the controller are integrated into a single unit. In another embodiment, the pump control apparatus may be self-powered.

Abstract: The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.

Abstract: Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site. Also disclosed is a method of stimulating the proliferation and expansion of chrondrocytes in vitro. The method comprises culturing chrondrocytes in the presence of a stimulating amount of an NPAR agonist.

Abstract: Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site. Also disclosed is a method of stimulating the proliferation and expansion of chrondrocytes in vitro. The method comprises culturing chrondrocytes in the presence of a stimulating amount of an NPAR agonist.

Abstract: Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site. Also disclosed is a method of stimulating the proliferation and expansion of chrondrocytes in vitro. The method comprises culturing chrondrocytes in the presence of a stimulating amount of an NPAR agonist.

Abstract: Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site.

Abstract: Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site.

Abstract: A method and apparatus for preparing an orthotic appliance to correct defects in a foot providing the steps of scanning a foot, creating a three-dimensional model of the corrected foot, milling a positive mold of the corrected foot, forming a uniformly thick orthotic material over the positive mold and milling out the bottom of the orthotic appliance. Also provided is a heel bisector for use in preparing an orthotic appliance.

Abstract: A method and apparatus for preparing an orthotic appliance to correct defects in a foot providing the steps of scanning a foot, creating a three-dimensional model of the corrected foot, milling a positive mold of the corrected foot, forming a uniformly thick orthotic material over the positive mold and milling out the bottom of the orthotic appliance. Also provided is a heel bisector for use in preparing an orthotic appliance.