Patents by Inventor John Bermel

John Bermel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacturing process for the production of peptides grown in insect cell lines
    Publication number: 20060246544
    Abstract: The present invention provides a manufacturing method for the production of peptides that are grown in insect cell lines. The peptides are grown in insect cell cultures that are infected with baculovirus particles in a culture supplemented with a lipid mixture. The peptides are then isolated from the insect cell culture using a method that employs a tangential flow filtration cascade. The isolated peptides are glycopeptides having an insect specific glycosylation pattern. The glycopeptides may then be conjugated to a modifying group via linkage through a glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase.
    Type: Application
    Filed: March 30, 2006
    Publication date: November 2, 2006
    Applicant: Neose Technologies,Inc.
    Inventors: Yun Kang, Walter Willett, Thomas Klimek, Basil Campbell, Paul Cino, Bradley Thomas, John Bermel, Chun-Chiang Chen