Abstract: The disclosure is directed to an electrosurgical generator comprising: an electromagnetic signal supply unit for generating electromagnetic, EM, energy to be conveyed along each of a plurality of channels. Each of the plurality of channels is arranged to convey electromagnetic energy at a different frequency. The electrosurgical generator further comprises an output port selectively connectable to each of the plurality of channels. The output port is connectable to an electrosurgical instrument for delivering the electromagnetic energy to biological tissue. The electrosurgical generator further comprises a tissue identification unit comprising a controller configured to: detect a signal indicative of a load impedance at the output port; determine a set of complex impedance values from the detected signals; identify a tissue type from the set of complex impedance values; and generate an output for communicating the identified tissue type to a user.

Abstract: Techniques are provided for a semi-flexible instrumentation mount for coupling an instrumentation module to a mounting location disposed on an aquatic vehicle. The semi-flexible instrumentation mount includes a support assembly comprising one or more support assembly components. The support assembly is configured to couple with the mounting location disposed on the aquatic vehicle. The semi-flexible instrumentation mount also includes an elastomeric segment comprising a vehicle end and an instrumentation end, a first rigid connector configured to couple the vehicle end of the elastomeric segment with the support assembly, and a second rigid connector configured to couple the instrumentation end of the elastomeric segment with the instrumentation module.

Abstract: It is provided method of transferring responsibility of a physical key (3) from a transferer (5a) to a transferee (5b). The method is performed by a transferee device (2b), being a user device (2b) of the transferee (5b). The method comprises: establishing (40) a local communication channel (4) with a user device (2a) of the transferer (5a): receiving (42), over the local communication channel (4), a request to register that the responsibility of the physical key (3) is transferred from the transferer (5a) to the transferee (5b): receiving (44) user input indicating that the responsibility of the physical key (3) is accepted by the transferee (5b); and transmitting (46) a confirmation of registration of transferring the responsibility of the physical key (3) to the transferee (5b).

Abstract: Packaging apparatus comprises two counter-rotatable sealing dies for pressing together two tissue webs to produce pockets for containing a substance for preparing beverages and to seal around the pockets, and two heating drums for heating the sealing dies and each being positioned inside a respective sealing die, wherein a first heating zone of each heating drum comprises a first plurality of circumferentially distributed infrared heating elements, and a second heating zone of each heating drum comprises a second plurality of circumferentially distributed infrared heating elements.

Abstract: It is provided a method for providing access to a vehicle. The method is performed by a vehicle determination device (1). The method comprises: receiving (40) a request signal, indicating a set of parameters of a desired vehicle; determining (42), from a first database (20), a plurality of candidate vehicles (2a-c) matching the set of parameters of a desired vehicles; determining (44), from a second database (21), for each one of the candidate vehicles (2a-c), a number of blocking vehicles (3) blocking access to the respective candidate vehicle; selecting (46) the candidate vehicle with the fewest number of blocking vehicles; and transmitting (48) a key release signal to release a physical key to the selected vehicle, to thereby provide access to the selected vehicle.

Abstract: The present invention provides a house system comprising a plurality of sensors, each configured to sense conditions of one or more house electrical or mechanical systems, one or more environmental conditions relating to the house, or a combination thereof; a plurality of devices, each configured to control the operation of one or more house electrical or mechanical systems; a compute module, comprising data storage local to the compute module and a programmed data processor configured to apply machine learning to develop a model of one or more conditions relating to the house, responsive to one or more of a plurality of conditions relating to the house; a communication interface configured to communicate information from the compute module with an external communications network accessible by one or more parties relating to the house.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: The invention relates to an electrosurgical instrument calorimeter for measuring an electromagnetic energy output of an electrosurgical instrument powered by a generator, comprising a calorimeter cell for containing an absorption material configured to absorb electromagnetic radiation, at least one temperature sensor configured to measure a temperature of the absorption material, and a support structure configured to hold the electrosurgical instrument in such a position that electromagnetic radiation emitted by the electrosurgical instrument is absorbed by the absorption material.

Abstract: An electrosurgical instrument capable of performing both thermal ablation and electroporation in a minimally invasive manner. The instrument is dimensioned to fit within an instrument channel of an endoscope to enable non-percutaneous insertion. The instrument comprises a radiating tip mounted at a distal end of a coaxial transmission line to receive microwave EM energy from the coaxial transmission line and emit it as a field around the radiating tip. The instrument further comprises an auxiliary transmission line arranged to convey electromagnetic energy having an electroporation waveform to a microelectrode array mounted on the radiating tip. The electroporation waveform may be a radiofrequency or low frequency electromagnetic (EM) signal. The microelectrode array may comprise a plurality of nanoscale conductive electrode elements.

Abstract: The disclosure relates to a sterilization apparatus which uses thermal or non-thermal plasma to disinfect surgical scoping devices such as endoscopes, gastroscopes, laparoscopes and the like. Aspect of the disclosure provide: (i) an apparatus for sterilizing inside an instrument channel formed with an insertion tube of a surgical scoping device, (ii) a whole-device sterilization apparatus for treating the entire exterior surface of a surgical scoping device, and (iii) an apparatus for cleaning and sterilizing a distal end face of an insertion tube of a surgical scoping device.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: A robot-assisted surgical system in which apparatus for providing electrosurgical functionality is directly mountable on or integrated within a robotic arm. The apparatus may be a detachable module or capsule, which may be movable between different robotic arms in the same environment. The apparatus may comprise a plurality of modules, each providing a different treatment modality. Depending on the procedure to be performed, a different module or combination of modules may be selected and mounted on one or more robotic arms.

Abstract: An electrosurgical generator capable of supplying energy in a waveform that causes electroporation in biological tissue. The electrosurgical generator may comprise an electroporation waveform supply unit that is integrated with an electromagnetic signal supply unit for generating microwave electromagnetic signals and radiofrequency electromagnetic signals for treatment. The electrosurgical generator may be configured to deliver different types of energy along a common feed cable. The electroporation waveform supply unit comprises a DC power supply and a DC pulse generator. The DC power supply may include a DC-DC converter for up-converting a voltage output by an adjustable voltage supply. Each DC pulse may have a duration in the range 1 ns to 10 ms and a maximum amplitude in the range 10 V to 10 kV.

Abstract: Packaging apparatus comprises two counter-rotatable sealing dies for pressing together two tissue webs to produce pockets for containing a substance for preparing beverages and to seal around said pockets, and two heating drums for heating the sealing dies and each being positioned inside a respective sealing die, wherein a first heating zone of each heating drum comprises a first plurality of circumferentially distributed infrared heating elements, and a second heating zone of each heating drum comprises a second plurality of circumferentially distributed infrared heating elements.

Abstract: An electrosurgical apparatus is provided having a rechargeable power source which may be charged wirelessly. The apparatus comprises an oscillator for generating electromagnetic (EM) energy (e.g. radiofrequency energy or microwave frequency energy); a controller operable to select an energy delivery profile for the oscillator; a feed structure for conveying the electromagnetic energy to an output; a rechargeable power source arranged to supply power to the oscillator; and a receiver circuit comprising an inductive coupler configured to wirelessly receive power from a transmitter and supply received power to the rechargeable power source. The selection of an energy delivery profile may involve switching the oscillator on or off in one example, or may comprise more complex operation such as the selection of a pulse profile in some embodiments.

Abstract: The inventive subject matter provides a device in which a pet stroller comprises at least three wheels, a battery, a motor, and a treadmill. The treadmill is positioned inside of the stroller and has a belt upon which an animal walk and run. The battery is configured to power the motor, and in at least some contemplated embodiments, movement of one or more of the wheels of the stroller can be used to directly move the belt of the treadmill, and/or indirectly power the belt by providing power to the battery.

Abstract: Sterilisation apparatus comprising a sterilisation instrument configured to be inserted through the instrument channel of a surgical scoping device and a withdrawal device for withdrawing the sterilisation instrument from the instrument channel at a predetermined rate. The sterilisation instrument comprises an elongate probe having a probe tip with a first electrode and a second electrode arranged to produce an electric field from received RF and/or microwave frequency EM energy. In operation the instrument may disinfect an inner surface of the instrument channel by emitting energy whilst being withdrawn through the channel.

Abstract: The invention relates to a modular electrosurgical system for using electromagnetic (EM) radiation, such as radio frequency (RF) or microwave EM radiation, to treat biological tissue. In one example, control of the modules is centralised in a remote computing device which can communicate wirelessly with the modules of the system. In one example, different optional modules may be combined together with core modules to provide the system with different electrosurgical capabilities.

Abstract: The inventive subject matter provides a device in which a pet stroller comprises at least three wheels, a battery, a motor, and a treadmill. The treadmill is positioned inside of the stroller and has a belt upon which an animal walk and run. The battery is configured to power the motor, and in at least some contemplated embodiments, movement of one or more of the wheels of the stroller can be used to directly move the belt of the treadmill, and/or indirectly power the belt by providing power to the battery.