Abstract: A data processing system for automated design of a piping system and method thereof are disclosed. In one embodiment, a method for automated design of a piping system includes obtaining logical definition data of the piping system with pipe runs from a computer-aided design (CAD) database, and computing a piping path for said each pipe run based on the logical definition data of the piping system. The method includes determining positions of the piping components required for said each pipe run according to the logical definition data based on the computed piping path, and associating the piping components for said each pipe run with the determined positions of the piping components. Moreover, the method includes automatically generating a graphical model of the piping system with the pipe runs based on the association of the piping components with the determined positions for said each pipe run.

Abstract: The present invention relates to novel triazolo-pyridines of the formula wherein X is >CH2, >NH, sulfur, >S?O, >SO2 or oxygen; wherein said >CH2 and >NH may optionally be substituted with a suitable substituent; R1 is selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; R2 is selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; s is an integer from 0-4; R3 is R4, R5—(NR6)—, R5—S—, R5—(S?O)—, R5—(SO2)—, R5—SO2—NR6—, R5—(NR6)—SO2—, R5—O—, R5—(C?O)—, R5—(NR6)—(C?O)—, R5—(C?O)—NR6—, R5—O—(C?O)—, R5—(C?O)—O—, R5—CR7?CR8— or R5—C?C_; such that the molecular weight of R3 is less than 500 AMU, preferably less than 250 AMU; R4, R5 and R6 are each selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; or a pharmaceutically acceptable salt thereof; to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use.