Patents by Inventor John Brash

John Brash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional Surface Modification of Biomaterials to Reduce Thrombosis
    Publication number: 20250325733
    Abstract: An antithrombotic surface-modified biomaterial is provided comprising a biomaterial substrate coated with a polymerizable dopamine-containing bioadhesive to which is attached one or more antithrombotic agents. A method of preparing the surface-modified biomaterial is also provided. The surface-modified biomaterial is beneficial for use in blood-contacting medical devices such as catheters, dialyzers and blood oxygenators to prevent or minimize the occurrence of thrombosis on the surface thereof.
    Type: Application
    Filed: May 24, 2023
    Publication date: October 23, 2025
    Inventors: Anthony Chan, John Brash, Kyla Sask, Ravi Selvaganapathy, Christoph Fusch, Gerhard Fusch, Niels Rochow, Salhab El Helou, Siyuan Li
  • Artificial placenta
    Patent number: 9492603
    Abstract: An artificial placenta oxygenating device for use with an infant is provided. The device comprises a first layer comprising a gas permeable membrane; and a second layer comprising a vascular network that permits circulation of fluid therethrough, wherein a portion of the gas permeable membrane is attached to and covers the vascular network, wherein the vascular network comprises an inlet that permits fluid flow into the vascular network and an outlet that permits fluid to flow out of the vascular network and wherein the inlet and outlet are positioned so that fluid flows through the vascular network and in contact with the gas permeable membrane to permit gas exchange to occur. Assemblies comprising a plurality of single artificial placenta devices is also provided.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: November 15, 2016
    Assignee: McMaster University
    Inventors: Christoph Fusch, Leslie Berry, Anthony Chan, Niels Rochow, Ponnambalam (Ravi) Selvaganapathy, John Brash, Gerhard Fusch
  • ARTIFICIAL PLACENTA
    Publication number: 20140255253
    Abstract: An artificial placenta oxygenating device for use with an infant is provided. The device comprises a first layer comprising a gas permeable membrane; and a second layer comprising a vascular network that permits circulation of fluid therethrough, wherein a portion of the gas permeable membrane is attached to and covers the vascular network, wherein the vascular network comprises an inlet that permits fluid flow into the vascular network and an outlet that permits fluid to flow out of the vascular network and wherein the inlet and outlet are positioned so that fluid flows through the vascular network and in contact with the gas permeable membrane to permit gas exchange to occur. Assemblies comprising a plurality of single artificial placenta devices is also provided.
    Type: Application
    Filed: August 23, 2012
    Publication date: September 11, 2014
    Inventors: Christoph Fusch, Leslie Berry, Anthony Chan, Niels Rochow, Ponnambalam (Ravi) Selvaganapathy, John Brash, Gerhard Fusch