Abstract: A method of repairing a mat including: cutting an irregular section of the mat to an approximately perpendicular edge; applying a sealant to the perpendicular edge; conjoining a secondary piece to the perpendicular edge; clamping the secondary piece to the perpendicular edge temporarily; and fixing the secondary piece to the perpendicular edge; where the mat being configured to support the weight of people, vehicles and equipment thereupon and undergo movement relative to one or more other mats without disengaging from another, and the mats include at least four sides and an edge extending along each side, the first and second sides of each mat having a lower lip extending horizontally outwardly below the edge thereof and the third and fourth sides of each mat having an upper lip forming the edge thereof, the respective upper and lower lips of different mats being interconnectable with pins.

Abstract: A method of repairing a mat including: cutting an irregular section of the mat to an approximately perpendicular edge; applying a sealant to the perpendicular edge; conjoining a secondary piece to the perpendicular edge; clamping the secondary piece to the perpendicular edge temporarily; and fixing the secondary piece to the perpendicular edge; where the mat being configured to support the weight of people, vehicles and equipment thereupon and undergo movement relative to one or more other mats without disengaging from another, and the mats include at least four sides and an edge extending along each side, the first and second sides of each mat having a lower lip extending horizontally outwardly below the edge thereof and the third and fourth sides of each mat having an upper lip forming the edge thereof, the respective upper and lower lips of different mats being interconnectable with pins.

Abstract: Described herein is a system and method of processing data of a digital twins object model. Data associated with a node of the digital twins object model is parsed to identify metadata associated with the node. The data can comprise telemetry data received from an IoT device associated with the node. User-defined function(s) are determined that match the identified metadata. The data and metadata can be provided to the user-defined function(s). The determined user-defined function(s) are executed. Also described herein is a method of creating a user-defined function for processing data of a digital twins object model. Information regarding business logic is received from a user defining a user-defined function. Information regarding telemetry condition(s) to which the user-defined function applies is received defining a matcher. The user-defined function and matcher are stored as objects within a spatial intelligence graph associated with the digital twins object model.

Abstract: This disclosure relates to recognition moieties, biosensors, biosensor systems and kits thereof, and the methods for their use in detecting a target nucleic acid molecule in a test sample, including viral RNA and methods for determining whether a subject has a viral infection. The methods disclosed herein include detecting a viral infection in a subject comprising testing a sample from the subject for the presence of a target nucleic acid using a biosensor system, wherein presence of a target nucleic acid indicates that the subject has a viral infection.

Abstract: A toy car storage device for storing toy cars has a storage body that is defined by a top edge, a bottom edge, a front edge, and a rear edge. A plurality of storage recesses is formed in the storage body, each of the storage recesses being sized and shaped to receive one of the toy cars. A plate frame is mounted adjacent the bottom edge of the storage body and has an upper ridge and a lower ridge which together form a plate receiving space therebetween. A plurality of plates may be slidably mounted in the plate receiving space and frictionally held between the upper and lower ridges of the plate frame. First and second slots are formed in the bottom edge, between the plate frame and the front edge of the storage body, for interlocking with first and second stabilizer stands each having interlocking portions and a pair of laterally extending legs.

Abstract: A door latch system comprises an interchangeable latch assembly for securing a door to a door frame. The interchangeable latch assembly comprises a head and a latch mounted to the head. The latch is moveable between latched and unlatched positions. A driven member is operatively connected to the latch, the driven member moveable to latch or unlatch the latch. The door latch system further comprises a universal actuating assembly removably couple-able to the interchangeable latch assembly. The universal actuating assembly comprises a mounting bracket and a driving member releasably coupled to the driven member. Actuation of the universal actuating assembly translates the driving member and the driven member, moving the latch to the unlatched position. A first interchangeable latch assembly may be swapped with a second interchangeable latch assembly without requiring modification of the universal actuating assembly.

Abstract: A door latch system comprises an interchangeable latch assembly for securing a door to a door frame. The interchangeable latch assembly comprises a head and a latch mounted to the head. The latch is moveable between latched and unlatched positions. A driven member is operatively connected to the latch, the driven member moveable to latch or unlatch the latch. The door latch system further comprises a universal actuating assembly removably couple-able to the interchangeable latch assembly. The universal actuating assembly comprises a mounting bracket and a driving member releasably coupled to the driven member. Actuation of the universal actuating assembly translates the driving member and the driven member, moving the latch to the unlatched position. A first interchangeable latch assembly may be swapped with a second interchangeable latch assembly without requiring modification of the universal actuating assembly.

Abstract: The present invention provides a binding moiety which selectively binds to Sox11 protein and/or mRNA for imaging, diagnosis or prognosis of epithelial ovarian cancer (EOC). Optionally, the moiety is an antibody or antigen-binding fragment thereof. Advantageously, moiety comprises a further, readily detectable moiety. The invention also provides methods of imaging EOC cells as well as methods of diagnosing or prognosing EOC in an individual. A further aspect of the present invention provides a method of identifying cells associated with EOC, the method comprising analysing the pattern of gene expression in a sample of cells to be tested and comparing it to the pattern of gene expression in a sample of known lymphomas cells. Preferably, the cells to be tested are identified as EOC cells if the expression of Sox11 is up-regulated compared to normal B-cells.

Abstract: A toy car storage device for storing toy cars has a storage body that is defined by a top edge, a bottom edge, a front edge, and a rear edge. A plurality of storage recesses is formed in the storage body, each of the storage recesses being sized and shaped to receive one of the toy cars. A plate frame is mounted adjacent the bottom edge of the storage body and has an upper ridge and a lower ridge which together form a plate receiving space therebetween. A plurality of plates may be slidably mounted in the plate receiving space and frictionally held between the upper and lower ridges of the plate frame. First and second slots are formed in the bottom edge, between the plate frame and the front edge of the storage body, for interlocking with first and second stabilizer stands each having interlocking portions and a pair of laterally extending legs.

Abstract: An electric door strike assembly includes a housing and at least one keeper arm. The housing has an opening for admission and retraction of a door latch. The at least one keeper arm has a latch portion and is mounted on the housing. The at least one keeper arm is movable between a closed position, where the opening is occluded by the latch portion, and an open position, where the door latch may be released from the opening. The latch portion may include a bifurcated member having inside and outside legs arranged in spaced parallel relation so as to define a gap therebetween. The gap is configured to receive a latch plate of an interlocking latch mechanism when the at least one keeper arm is in the closed position.

Abstract: A latch dogging assembly comprises an electromagnet and an actuator mounted on a bracket. A guide slide is pivotally mounted on the bracket with a lead block coupled to the guide slide. A guide pin rides along an inner surface of the bracket causing the guide slide to pivot. A pawl is slidably engaged with the guide slide. A guide link includes a post. An armature is mounted to the panic bar and the post engages the pawl. When the actuator is energized to move the lead block, the pawl engages the post to pivot the armature and thereby cause the panic bar to move from the extended position to the depressed position. When the electromagnet is energized the armature is magnetically held preventing reverse pivoting of the guide link. A method for fully retracting a door latch is also provided.

Abstract: A multi-seat gate valve with a pair of sealing members separated by a gate wherein each sealing member is secured between a bottom edge surface on the gate and a pair of locking members until the gate valve is at a fully closed position and proper seating is achieved.

Abstract: A multi-seat gate valve with a pair of sealing members separated by a gate wherein each sealing member is secured between a bottom edge surface on the gate and a pair of locking members until the gate valve is at a fully closed position and proper seating is achieved.

Abstract: A latch dogging assembly comprises an electromagnet and an actuator mounted on a bracket. A guide slide is pivotally mounted on the bracket with a lead block coupled to the guide slide. A guide pin rides along an inner surface of the bracket causing the guide slide to pivot. A pawl is slidably engaged with the guide slide. A guide link includes a post. An armature is mounted to the panic bar and the post engages the pawl. When the actuator is energized to move the lead block, the pawl engages the post to pivot the armature and thereby cause the panic bar to move from the extended position to the depressed position. When the electromagnet is energized the armature is magnetically held preventing reverse pivoting of the guide link. A method for fully retracting a door latch is also provided.

Abstract: The present application is directed to biosensors and methods for detecting a microorganism target in a sample using a mechanically interlocked nucleic acid catanane, wherein an enzyme from the microorganism target or that is activated by a molecule from the microorganism target cleaves a linkage in a first single-stranded nucleic acid ring of the catanane structure, allowing rolling-circle amplification to occur and the presence of rolling-circle amplification products indicates the presence of the microorganism in the sample.

Abstract: An exit device has an overall height when a panic bar of the exit device is in its extended position. The exit device is configured to be received, at least in part, within a recess defined within a body of the door so that the height at which the extended panic bar protrudes beyond an outer surface of the door is reduced.

Abstract: A program model that includes requirements and control objects associated with requirements, workflows, proof assets. Workflow tasks associated with the workflows may generate requests to collect each proof asset associated with the control objects. Workflow tasks may validate each collected proof asset based on the plurality of control objects associated with each collected proof asset. Workflow tasks may determine completed control objects based on the validated proof assets. Workflow tasks may employ an amount of the completed control objects that is equivalent to the amount of the control objects associated with the program model to provide a report indicating that the requirements associated with the program model may be satisfied. Workflow tasks may employ detection of modifications to the validated proof assets to determine a portion of the workflow tasks based on the modified proof assets such that the portion of the workflow tasks may be re-executed.

Abstract: An exit device has an overall height when a panic bar of the exit device is in its extended position. The exit device is configured to be received, at least in part, within a recess defined within a body of the door so that the height at which the extended panic bar protrudes beyond an outer surface of the door is reduced.

Abstract: Provided herein are methods for selection of circular aptamers using a circular nucleic acid library. Also provided are circular aptamers, circular aptamer probes, biosensor systems, and the methods for their use in detecting a microorganism target, or a target molecule present on or generated from a microorganism or a virus in a test sample, including C. difficile glutamate dehydrogenase and methods for determining whether a subject has a C. difficile infection.

Abstract: Described is an approach that takes advantage of rolling circle amplification (RCA) and an RNA-cleaving DNAzyme (RCD) to achieve massive signal amplification for biosensing via a cross-feedback mechanism. An RCA reaction generates copies of an RCD that triggers a reaction cascade designed to generate additional DNA assemblies for RCA. These cross-feedback actions work autonomously to turn limited molecular recognition events into massive amounts of DNA amplicons that can be conveniently detected. This approach was demonstrated for biosensing of a microRNA sequence and a bacterium.