Patents by Inventor John Brew

John Brew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120128738
    Abstract: The present invention is theobromine as an active agent to be delivered via the inhaled route, for the treatment of cough.
    Type: Application
    Filed: June 15, 2010
    Publication date: May 24, 2012
    Inventors: John Brew, Robin Mark Bannister
  • Publication number: 20120125325
    Abstract: An agent, which is amlexanox, is useful in the therapy of a disease associated with neutrophilia.
    Type: Application
    Filed: May 28, 2010
    Publication date: May 24, 2012
    Inventors: Robin Mark Bannister, John Brew
  • Patent number: 8030357
    Abstract: Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (I) or a salt thereof.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: October 4, 2011
    Assignee: Biocopea Limited
    Inventors: John Brew, Robin Mark Bannister, Andrew Douglas Baxter
  • Publication number: 20090318562
    Abstract: Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (1) or a salt thereof.
    Type: Application
    Filed: March 9, 2007
    Publication date: December 24, 2009
    Applicant: SOSEI R & D LTD.
    Inventors: John Brew, Robin Mark Bannister, Andrew Douglas Baxter
  • Publication number: 20090306216
    Abstract: A compound for therapeutic use, of the formula (I), wherein R1 is aryl or heteroaryl optionally substituted with R5; R2 is H, alkyl or CH2OH or forms part of a ring with R4; R3 is H, alkyl or CH2OH or forms part of a ring with R4; R4 is H, alkyl or (when forming part of a ring with R2 or R3) CH2; and R5 is alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2Me, CONH2, or SOMe; or a salt thereof.
    Type: Application
    Filed: March 9, 2007
    Publication date: December 10, 2009
    Inventors: John Brew, Andrew Douglas Baxter, Robin Mark Bannister
  • Publication number: 20090137686
    Abstract: Beta-amino alcohols are useful for the treatment of ophthalmic conditions.
    Type: Application
    Filed: November 24, 2006
    Publication date: May 28, 2009
    Inventors: Alan Rothaul, John Brew
  • Publication number: 20080096971
    Abstract: Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (I): wherein R1 is CHR4—OR5 or CHR4—SR5, or aryl or heteroaryl optionally substituted with one or more groups R6; R2 is alkyl or is part of a ring with R3; R3 is H, alkyl or CH2 (when forming part of a ring with R2); R4 is H or alkyl or is part of a ring with R5; R5 is aryl or heteroaryl optionally substituted with R7; each R6 is independently alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2alkyl, CONH2, SOMe, SO2NH2, Salkyl, CH2SO2alkyl or OCONalkyl2; R7 is R8 or (CH2)nOR8, R9, CF3, OH, OR9, OCOR9, COR9, COOR9, CONH2, CH2CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHCONHR7, NHCON(R9)2, NHCOR9, NHCOaryl, NHSO2Me, CONH2, SMe, SOMe Or SO2NH2; R8 is (CH2)nOR9, (CH2)nOR9, (CH2)nCOOR9 or (CH2)nCOaryl; R9 is alkyl or cycloalkyl; and n is 1 to 4; or a salt thereof.
    Type: Application
    Filed: September 7, 2005
    Publication date: April 24, 2008
    Inventors: Andrew Baxter, John Brew
  • Publication number: 20080076827
    Abstract: Actarit or a salt thereof is useful for the treatment of inflammatory bowel disease.
    Type: Application
    Filed: October 20, 2005
    Publication date: March 27, 2008
    Inventors: John Brew, Robin Mark Bannister
  • Publication number: 20070179181
    Abstract: A compound that has utility in the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro- and/or anti-inflammatory cytokines, is of formula (I) wherein R1 is H or Me; R2 is H or alkyl and R3 is H or Me, or R2 and R3 are —CH2— thereby forming a ring; n is 0 to 2; X is CH2 or O; and the two benzene rings are each optionally substituted with OH, OMe, Halogen, NHCHO, NHSO2Me, CONH2, SOMe OCH2O or CH2OH.
    Type: Application
    Filed: March 17, 2005
    Publication date: August 2, 2007
    Inventors: Andrew Baxter, John Brew
  • Publication number: 20070043111
    Abstract: Ifenprodil is useful for the treatment of pain.
    Type: Application
    Filed: October 21, 2004
    Publication date: February 22, 2007
    Inventors: John Brew, Robin Bannister, Andrew Baxter, Alan Rothaul, Michael Lyne
  • Publication number: 20070043112
    Abstract: A non-opioid analgesic is used for the treatment of intermittent or episodic pain experienced by a patient undergoing chronic pain treatment with an opioid analgesic.
    Type: Application
    Filed: October 21, 2004
    Publication date: February 22, 2007
    Inventors: John Brew, Robin Bannister, Andrew Baxter, Alan Rothaul, Michael Lyne
  • Publication number: 20050222205
    Abstract: Ifenprodil is useful for the treatment of pain, e.g. on administration intranasally or by another route that avoids first-pass metabolism.
    Type: Application
    Filed: May 6, 2003
    Publication date: October 6, 2005
    Inventors: John Brew, Robin Bannister, Andrew Douglas Baxter, Alan Rothaul, Michael Lyne