Patents by Inventor John Brian Mumm

John Brian Mumm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of pegylated IL-10 to treat cancer
    Patent number: 9833514
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: December 5, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Martin Oft, Catherine Sheppard, John Brian Mumm, Lingling Wu
  • Method for assessing protein identity and stability
    Patent number: 9823255
    Abstract: The present invention relates to methods and other technologies that may be used to determine whether compositions (e.g., pharmaceutical compositions) comprising interleukin-10 molecules (e.g., pegylated interleukin-10) meet particular product-related specifications prior to being administered to a subject for the treatment and/or prevention of the diseases, disorders and conditions, and/or the symptoms thereof, described herein.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: November 21, 2017
    Assignee: ARMO BioSciences, Inc.
    Inventors: John Brian Mumm, Peter Van Vlasselaer
  • Methods of Lowering Serum Cholesterol
    Publication number: 20170296653
    Abstract: Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to agents modulating Kupffer cell function, including methods of administration and dosing regimens associated therewith, are provided. Methods of treating subjects having liver diseases, disorders, or conditions, including non-alcoholic steatohepatitis and non-alcoholic fatty liver disease, with an IL-10 agent are also provided.
    Type: Application
    Filed: May 6, 2015
    Publication date: October 19, 2017
    Inventors: John Brian Mumm, Ivan Ho Chan
  • Use of Pegylated IL-10 to Treat Cancer
    Publication number: 20160367689
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Application
    Filed: May 16, 2016
    Publication date: December 22, 2016
    Inventors: Martin Oft, Catherine Sheppard, John Brian Mumm, Lingling Wu
  • Methods of Using Interleukin-10 for Treating Diseases and Disorders
    Publication number: 20160361415
    Abstract: Methods of modulating immune responses in subjects having oncology- and immune-related diseases, disorders and conditions by the administration of an IL-10 agent, including pegylated IL-10.
    Type: Application
    Filed: May 26, 2016
    Publication date: December 15, 2016
    Inventors: John Brian Mumm, Ivan Ho Chan
  • Methods of Using Interleukin-10 for Treating Diseases and Disorders
    Publication number: 20160243196
    Abstract: Methods of treating subjects having diseases, disorders, or conditions, including cancer and immune- and inflammatory-related disorders, via the administration of IL-10 in combination with one or more additional agents, and methods and models associated therewith, are provided.
    Type: Application
    Filed: November 7, 2014
    Publication date: August 25, 2016
    Inventors: John Brian Mumm, Ivan Ho Chan, Martin Oft
  • Methods of Using Interleukin-10 for Treating Diseases and Disorders
    Publication number: 20160193300
    Abstract: Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to IL-10, including methods of administration and dosing regimens associated therewith, are provided, More particularly, the present disclosure relates to optimized dosing parameters to achieve and maintain efficacy in the treatment and/or prevention of metabolic diseases, disorders and conditions in a subject, while minimizing the adverse effects associated therewith. Particular embodiments are directed to the treatment and/or prevention of abnormally high levels of cholesterol and/or manifestation(s) of hypercholesterolemia in as subject.
    Type: Application
    Filed: August 26, 2014
    Publication date: July 7, 2016
    Inventors: John Brian Mumm, Ivan Ho Chan
  • Method of treatment of lymphoma with pegylated IL-10
    Patent number: 9364517
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: June 14, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Martin Oft, Catherine Sheppard, John Brian Mumm, Lingling Wu
  • Method for Assessing Protein Identity and Stability
    Publication number: 20160123991
    Abstract: The present invention relates to methods and other technologies that may be used to determine whether compositions (e.g., pharmaceutical compositions) comprising interleukin-10 molecules (e.g., pegylated interleukin-10) meet particular product-related specifications prior to being administered to a subject for the treatment and/or prevention of the diseases, disorders and conditions, and/or the symptoms thereof, described herein.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 5, 2016
    Inventors: John Brian Mumm, Peter Van Vlasselaer
  • Use of Pegylated IL-10 to Treat Cancer
    Publication number: 20150079031
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Application
    Filed: September 12, 2014
    Publication date: March 19, 2015
    Inventors: Martin Oft, Catherine Sheppard, John Brian Mumm, Lingling Wu