Abstract: A connector assembly includes a plurality of receptacle modules configured to be received in corresponding module channels in a receptacle cage. Each receptacle module has a housing holding a contact assembly. The housing has a card slot at a front of the housing. The contact assembly has contacts terminated to ends of cables. The contacts have mating ends at the card slot to mate with a pluggable module received in the receptacle cage. The connector assembly includes an integrator having integrator walls forming a plurality of chambers. Each chamber receives the corresponding receptacle module. The connector assembly includes a latch coupled to the integrator. The latch configured to be latchably coupled to the receptacle cage.

Abstract: The present invention relates to an apparatus for the disaggregation of tissue. The apparatus comprises a first cutting zone comprising a first cutting blade configured to rotate about a first rotational axis, and an opening for the ingress of tissue. The opening is oriented at an angle to the first rotational axis.

Abstract: A magnetically coupled drive module for delivering an implant to an eye. An implant may be stored, advanced, and delivered to an eye using a powered drive module. The drive module may be decoupled and sterilized for reuse.

Abstract: The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.

Abstract: The present disclosure relates to a method for entraining in an airflow a medicament powder contained in a cavity having a cavity opening. Large airflow vortices are provided, for instance, by use of an obstacle in a flow passage, The airflow with large vortices is arranged to by-pass the cavity opening, thereby generating an eddy in the cavity which contributes to entraining the powder in said airflow. The present disclosure also relates to a medical dispenser, for instance an inhaler, in which the method may be performed.

Abstract: An inhaler including an outlet and a plurality of sealed compartments containing medicament is disclosed. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. A method of priming an inhaler and a method of dispensing a medicament from an inhaler is also disclosed.

Abstract: An inhaler, including a base having at least one air-tight, foil-sealed cavity containing medicament is disclosed. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. A method of dispensing a medicament from a sealed cavity inside an inhaler is also disclosed.

Abstract: The present invention relates to an inhaler, comprising a base having at least one air-tight, foil-sealed cavity containing medicament. An actuator is engagable with a separating element attached to the foil, the actuator having an energized position in which it is biased towards an unloaded position so as to cause the separating element and attached foil to be moved away from the cavity. A latch has a first position, in which it latches the actuator in said energized position, wherein the latch is at least partly arranged in a flow path such that an inhalation flow through the flow path affects the latch to move from the first position to the second position. The invention also relates to a method of dispensing a medicament from a sealed cavity inside an inhaler.

Abstract: The disclosure relates to an inhaler, comprising an outlet and a plurality of sealed compartments containing medicament. An opening mechanism is provided to open the compartment presently aligned with the outlet. An indexing mechanism sequentially aligns the compartments with the outlet. A latch is provided for latching the opening mechanism in an energized position. The latch cannot latch the opening mechanism before the indexing mechanism has aligned the next compartment with the outlet. The disclosure also relates to a method of priming an inhaler and a method of dispensing a medicament from an inhaler.

Abstract: The disclosure relates to a medical dispenser, comprising an outlet and a plurality of sealed compartments containing medicament to be sequentially aligned with and dispensed through said outlet. Movement of an actuator sequentially causes mechanical energy to be built up and then released and converted into an indexing movement of the compartments. The disclosure also relates to an indexing method for a medical dispenser.

Abstract: The disclosure relates to an inhaler comprising an outlet through which doses of medicament may be dispensed. The inhaler also comprises a dispensing mechanism having a primed state, in which it is ready for dispensing a dose, and a fired state, in which it has dispensed a dose. In one aspect, the inhaler also comprises a disabler which, after the final dose has been dispensed, is activated to disable the dispensing mechanism from generating a sound which has been audible when the dispensing mechanism has moved from its primed state to its fired state. In a second aspect, the disabler prevents the dispensing mechanism from being in its primed state when an outlet cover is in an open position, whereby a not ready indication is presented to the user.

Abstract: The invention relates to a method for entraining in an airflow a medicament powder contained in a cavity having a cavity opening. Large airflow vortices are provided, for instance, by means of an obstacle in a flow passage. The airflow with large vortices is arranged to by-pass the cavity opening, thereby generating an eddy in the cavity which contributes to entraining the powder in said airflow. The invention also relates to a medical dispenser, for instance an inhaler, in which said method may be performed.

Abstract: Optoelectronic components, specifically, ceramic optical sub-assemblies are described. In one aspect, the optoelectronic component includes a ceramic base substrate having a pair of angled (or substantially perpendicular) faces. The electrical traces are formed directly on the ceramic surfaces and extend between the pair of faces. A semiconductor chip assembly is mounted on the first face of the ceramic base substrate and a photonic device is mounted on the second face. Both the semiconductor chip assembly and the photonic device are electrically connected to traces on the ceramic base substrate. The semiconductor chip assembly is generally arranged to be electrically connected to external devices. The photonic devices are generally arranged to optically communicate with one or more optical fibers. The described structure may be used with a wide variety of photonic devices.

Abstract: Concepts for conveniently arranging devices for the transduction of signals to and from voltage and current domains to infrared radiation domains is described. Specifically, optoelectronic components and methods of making the same are described. In one aspect, the optoelectronic component includes a base substrate having a pair of angled (or substantially perpendicular) faces with electrical traces extending therebetween. A semiconductor chip assembly is mounted on the first face of the base substrate and a photonic device is mounted on the second face. Both the semiconductor chip assembly and the photonic device are electrically connected to traces on the base substrate. The semiconductor chip assembly is generally arranged to be electrically connected to external devices. The photonic devices are generally arranged to optically communicate with one or more optical fibers. The described structure may be used with a wide variety of photonic devices.

Abstract: A microfluidic system comprising a microchannel (2), a pressurised reservoir (3-5) of fluid and a positive displacement pump (7-9) downstream of the reservoir for pumping the fluid from the reservoir to the microchannel.