Abstract: A haircare appliance is described comprising a barrel around which hair may be wrapped, a heating element for heating the barrel, a sensor for sensing a parameter indicative of the presence or absence of hair in contact with the barrel, and a controller. The controller is configured to determine the presence or absence of hair in contact with the barrel based on data output by the sensor and control a supply of electrical power to the heating element based on the determination.

Abstract: A peptide that binds to elongation initiation factor 4E (eIF4E) comprising the amino acid sequence CEX1GX2X3X4X5C (SEQ ID NO: 1), where X1 is an amino acid selected from the group consisting of threonine (T), methionine (M) or leucine (L), X2 and X3 is an amino acid selected from the group consisting of phenylalanine (F), modified phenylalanine and tyrosine (Y), X4 and X5 is any amino acid, wherein the two cysteine residues are joined by a disulphide bond. Further, pharmaceutical compositions and uses of the peptide, and pharmaceutical compositions are provided.

Abstract: Devices, systems and techniques are used for cancer treatment. An example control device may be configured to be communicatively coupled to a radiation source of a radiotherapy device and a position sensor of the radiotherapy device. The example control device may be used to calculate, for a sliding window of a radiotherapy treatment, a positional error between: a measured target position signal determined from a series of images and sampled at the acquisition times of the images, and an estimated target position signal. The example control device may generate a computer-executable instruction configured to alter the radiotherapy treatment in response to the positional error violating a threshold.

Abstract: Systems, apparatus, articles of manufacture, and methods are disclosed to manage network notifications. An example apparatus includes interface circuitry, machine-readable instructions, and at least one processor circuit to be programmed by the machine-readable instructions to cause transmission of a first signal based on a packet, the first signal including characteristics of the packet, and cause transmission of a second signal after the first signal, the second signal including a payload of the packet.

Abstract: Memory management for wireless networks is described. A method, includes accessing an operational parameter for a network slice of a wireless network, determining a first memory region of a plurality of memory regions in the memory pool based on the operational parameter, and encoding configuration information to allocate the first memory region to the network slice. Other embodiments are described and claimed.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.

Abstract: A biopharmaceutical flow port, a biopharmaceutical liquid container assembly, and a method for manufacturing the biopharmaceutical flow port and the biopharmaceutical liquid container assembly are described. The biopharmaceutical flow port includes a hose barb coupled to an elliptic body. The hose barb includes a bore. The elliptic body includes a flow passage, a first edge, and a second edge. The flow passage is fluidly coupled to the bore. The first edge extends from the elliptic body away from the flow passage in a first direction and the second edge extends from the elliptic body away from the flow passage in a second direction opposite the first direction. The biopharmaceutical liquid container assembly includes a biopharmaceutical liquid container with an opening and the biopharmaceutical flow port coupled to the biopharmaceutical liquid container within the opening and in fluid communication with a volume of the biopharmaceutical liquid container.

Abstract: The present invention relates to the a coating and the preparation thereof for improving glass strength and fracture toughness comprising the hydrolytic polycondensation product of one or more alkoxysilane(s) with one or more metal oxide(s) and/or metal alkoxide(s) in the presence of water and a catalyst. The present invention also relates to the use of the coating for repairing damaged silica containing materials.

Abstract: A circuit arrangement includes a preprocessing circuit configured to obtain context information related to a user location, a learning circuit configured to determine a predicted user movement based on context information related to a user location to obtain a predicted route and to determine predicted radio conditions along the predicted route, and a decision circuit configured to, based on the predicted radio conditions, identify one or more first areas expected to have a first type of radio conditions and one or more second areas expected to have a second type of radio conditions different from the first type of radio conditions and to control radio activity while traveling on the predicted route according to the one or more first areas and the one or more second areas.

Abstract: A biopharmaceutical flow port, a biopharmaceutical liquid container assembly, and a method for manufacturing the biopharmaceutical flow port and the biopharmaceutical liquid container assembly are described. The biopharmaceutical flow port includes a hose barb coupled to an elliptic body. The hose barb includes a bore. The elliptic body includes a flow passage, a first edge, and a second edge. The flow passage is fluidly coupled to the bore. The first edge extends from the elliptic body away from the flow passage in a first direction and the second edge extends from the elliptic body away from the flow passage in a second direction opposite the first direction. The biopharmaceutical liquid container assembly includes a biopharmaceutical liquid container with an opening and the biopharmaceutical flow port coupled to the biopharmaceutical liquid container within the opening and in fluid communication with a volume of the biopharmaceutical liquid container.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to control execution of tasks in a computing system. The methods, apparatus, systems and articles of manufacture include at least one storage device and at least one processor to, execute instructions to at least obtain a request to perform an inverse operation on a data flow, the data flow previously transformed during a forward operation, determine a first processor core that executed the forward operation, the data flow including an identifier of the first processor core, and transmit the data flow to a second processor core to perform the inverse operation.

Abstract: The invention relates to retention systems for retaining items during use of a mobility chair. According to one embodiment, a mobility chair includes a frame, wheels and a seat; and an item retention system including one or more retractable straps such that when, in use, a user is positioned on the seat, the one or more retractable straps are arranged to be extended and secured to retain one or more items positioned on the user's lap or on the seat in front of the user. A related method of retaining an item or items on the user's lap is also described.

Abstract: A heating circuit has at least three series-connected resistance-heating elements, each resistance-heating element being connected between a pair of nodes, each pair of adjacent resistance-heating elements in the series being connected via one of the nodes, each node being connectable to a voltage. Optionally, the heating circuit may have one or more switching elements to allow selective connection of one or more voltages to the resistance heating elements.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Abstract: A device and method are presented. Largest and smallest successful values of a receive clock delay and a transmit clock delay are determined. A first set of parameters for an SPI coupled to a DDR flash memory are set, including the largest successful values of the transmit clock delay and the receive clock delay, and a first value of a RD cycle. A second set of parameters for the SPI are set, including the smallest successful value of the transmit clock delay and receive clock delay, and a second value of the RD cycle. One of the first and second sets of parameters is selected based on whether the first or second set of parameters results in successfully reading from the DDR flash memory over a larger range of operating temperatures. The SPI is programmed using the selected one of the first and second sets of parameters.

Abstract: Methods to automatically prioritize input/output (I/O) for Network Function Virtualization (NFV) workloads at platform overload and associated apparatus and mechanisms. During lab or runtime workload operations, various platform telemetry data are collected and analyzed to determine whether a current workload is uncore-sensitive—that is, sensitive to operations involving utilization of the uncore circuitry such as I/O-related operations, memory bandwidth utilization, LLC utilization, network traffic, core-to-core traffic etc. For uncore sensitive workloads, upon detection of a platform overload condition such as a thermal load approaching a TDP limit, the uncore circuitry is prioritized over the core circuitry such that the frequency of the core is reduced first. A closed-loop feedback mechanism is used to adjust the frequencies of the core and uncore under various workload conditions. The mechanism enables I/O throughput to be maintained for NFV workloads, while reducing the processor thermal load.

Abstract: Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.

Abstract: An extrusion process for creating a roof ditch molding including forming a main body from a plastic material in a first stage extrusion, conveying the main body through a stacked array of die plates and into a first stage cooling tank, and communicating the main body from an outlet of the first stage cooling tank to a second stage extruder with crosshead die for applying a skim film bonding layer to the main body. Additional steps include applying a decorative layer over the skim bonding layer, communicating the main body to a third stage extruder with cross head die for applying wing portions in partially overlapping fashion along opposite side edges of the decorative layer and drawing the completed ditch molding through a second stage cooling tank prior to conducting one or more finishing operations.