Patents by Inventor John Brozek

John Brozek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated pattern recognition and scoring method of histological images
    Patent number: 11676269
    Abstract: The present invention relates to a novel automated pattern recognition and scoring method of histological images.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: June 13, 2023
    Assignee: GENFIT
    Inventors: John Brozek, Nathalie Degallaix, Benoit Noel, Elton Rexhepaj
  • METHODS FOR DIAGNOSING AND EVALUATING NON-ALCOHOLIC STEATOHEPATITIS
    Publication number: 20220411874
    Abstract: The invention relates to a method for the diagnosis of non-alcoholic steatohepatitis (NASH), for determining the activity, the stage, or the severity of NASH or for classifying a subject as a potential receiver or non receiver of a treatment of NASH using circulating miRNAs and other blood circulating markers of liver damage, e.g. alpha 2 macroglobulin, HbA1c, N-terminal pro-peptide of collagen type III, miR-34 and miR-200. It also relates to a kit for implementing the method of the invention, and the compounds for use in a method for the treatment of NASH, wherein the subject to be treated is identified, evaluated or classified according to the method of the invention.
    Type: Application
    Filed: June 24, 2022
    Publication date: December 29, 2022
    Applicant: Genfit
    Inventors: Raphaël Darteil, Geneviève Cordonnier, John Brozek, Emilie Praca, Fouad Ben Sudrik
  • Non-invasive diagnostic of non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis and/or liver fibrosis
    Patent number: 11519034
    Abstract: The present invention relates to a novel non-invasive method for the diagnosis of a non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, and/or liver fibrosis.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: December 6, 2022
    Assignee: Genfit
    Inventors: Remy Hanf, Genevieve Cordonnier, John Brozek
  • METHOD FOR TREATMENT OF AT RISK PATIENTS
    Publication number: 20220241232
    Abstract: The invention provides an anti-fibrotic or anti-nonalcoholic steatohepatitis (NASH) drug for use in a method for reducing the risk for a subject to develop liver fibrosis or NASH, wherein the drug is administered to a subject classified as at risk to develop liver fibrosis or NASH. The invention further provides an anti-fibrotic or anti-NASH substance for use in a method for the treatment of liver fibrosis or NASH, wherein the drug is administered to a subject having type 2 diabetes.
    Type: Application
    Filed: June 8, 2020
    Publication date: August 4, 2022
    Inventors: JOHN BROZEK, NOÉMIE DAM, YACINE HAJJI, RÉMY HANF
  • Methods for diagnosing and evaluating non-alcoholic steatohepatitis
    Patent number: 11371098
    Abstract: The invention relates to a method for the diagnosis of non-alcoholic steatohepatitis (NASH), for determining the activity, the stage, or the severity of NASH or for classifying a subject as a potential receiver or non receiver of a treatment of NASH using circulating miRNAs and other blood circulating markers of liver damage, e.g. alpha 2 macroglobulin, HbA1c, N-terminal pro-peptide of collagen type III, miR-34 and miR-200. It also relates to a kit for implementing the method of the invention, and the compounds for use in a method for the treatment of NASH, wherein the subject to be treated is identified, evaluated or classified according to the method of the invention.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: June 28, 2022
    Assignee: Genfit
    Inventors: Raphaël Darteil, Geneviève Cordonnier, John Brozek, Emilie Praca, Fouad Ben Sudrik
  • DIAGNOSIS OF NON-ALCOHOLIC STEATOHEPATITIS
    Publication number: 20220162702
    Abstract: The present invention relates to a non-invasive method for classifying a subject as a potential receiver or non-receiver of a treatment for non-alcoholic steatohepatitis.
    Type: Application
    Filed: March 12, 2020
    Publication date: May 26, 2022
    Inventor: JOHN BROZEK
  • AUTOMATED PATTERN RECOGNITION AND SCORING METHOD OF HISTOLOGICAL IMAGES
    Publication number: 20210192722
    Abstract: The present invention relates to a novel automated pattern recognition and scoring method of histological images.
    Type: Application
    Filed: October 19, 2018
    Publication date: June 24, 2021
    Inventors: John Brozek, Nathalie Degallaix, Benoit Noel, Elton Rexhapaj
  • NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC FATTY LIVER DISEASES, NON-ALCOHOLIC STEATOHEPATITIS AND/OR LIVER FIBROSIS
    Publication number: 20200248261
    Abstract: The present invention relates to a novel non-invasive method for the diagnosis of a non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, and/or liver fibrosis.
    Type: Application
    Filed: August 27, 2018
    Publication date: August 6, 2020
    Inventors: Remy HANF, Genevieve CORDONNIER, John BROZEK
  • NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC FATTY LIVER DISEASES, NON-ALCOHOLIC STEATOHEPATITIS AND/OR LIVER FIBROSIS
    Publication number: 20200216901
    Abstract: The present invention relates to a novel non-invasive method for the diagnosis of a non-alcoholic fatty liver disease, in particular non-alcoholic steatohepatitis, and/or liver fibrosis.
    Type: Application
    Filed: September 14, 2018
    Publication date: July 9, 2020
    Applicant: Genfit
    Inventors: Remy HANF, Genevieve CORDONNIER, John BROZEK
  • NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC STEATOHEPATITIS
    Publication number: 20190352715
    Abstract: The invention relates to a novel method for the diagnosis of non-alcoholic steatohepatitis (NASH), and for classifying a subject as a potential receiver of a treatment for NASH.
    Type: Application
    Filed: March 30, 2017
    Publication date: November 21, 2019
    Applicant: Genfit
    Inventors: Raphael Darteil, Geneviève Cordonnier, John Brozek, Emilie Praca, Fouad Ben Sudrik