Patents by Inventor John-Bruce De Vault Green

John-Bruce De Vault Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for measuring intramolecular forces by atomic force
    Patent number: 5958701
    Abstract: A method is disclosed for measuring intramolecular forces within a sample compound by providing an atomic force microscope that includes a sample support member and a cantilever. The sample support member has a plurality of protrusions, and each protrusion has an apical substrate region that has been chemically modified to have a sample compound immobilized thereon. The cantilever has a fixed end and a free end, the free end having a surface region that has been chemically modified to have a grasping compound immobilized thereon. To measure intramolecular forces within the sample compound, the relative position and orientation of the cantilever and the sample support member are controlled to select a particular protrusion and to allow a molecule of the grasping compound to bind with a molecule of the sample compound.
    Type: Grant
    Filed: January 27, 1999
    Date of Patent: September 28, 1999
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: John-Bruce De Vault Green, Alexey Novoradovsky, Gil U. Lee