Abstract: Provided herein are anti-KRas antibodies that bind to mutant KRas-GDP and alkylated mutant KRas-GDP and methods of using the same. Also provide herein are method of screening for KRas inhibitors and methods of measuring binding of KRas to the antibodies described herein.

Abstract: An apparatus for obtaining radiant energy from a polychromatic radiant energy source has a spectral separator with a first curved surface concave to the incident radiant energy and treated to reflect a first spectral band toward a first focal region and to transmit a second spectral band and a second curved surface concave to the incident radiant energy and treated to reflect the second spectral band toward a second focal region. The first and second curved surfaces are optically positioned so that the first and second focal regions are spaced apart from each other. There are first and second light receivers, wherein the first light receiver is disposed nearest the first focal region for receiving the first spectral band and the second light receiver is disposed nearest the second focal region for receiving the second spectral band.

Abstract: An apparatus for obtaining energy from a polychromatic radiant energy source has a light concentrator for concentrating and redirecting incident radiant energy, having an optical axis, and a spectral separator disposed along the optical axis, apart from the light concentrator and in the path of concentrated, redirected radiant energy. The spectral separator has a first planar surface treated to reflect a first spectral band of light toward a first focal region and to transmit a second spectral band and a second planar surface spaced apart from the first planar surface and oblique with respect to the first planar surface. The second planar surface is treated to reflect the second spectral band back through the first planar surface and toward a second focal region spaced apart from the first focal region. First and second light receivers are disposed nearest each respective focal region for receiving the first and second spectral bands.

Abstract: Rotational motions between a displacement-measuring probe and an optical test surface define a spherical or near spherical datum surface against which measurements of the probe are taken. The probe has a measurement axis that is maintained substantially normal to the optical test surface during the course of measurement.