Patents by Inventor John C. Arruda

John C. Arruda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybridization-ligation assays for the detection of specific nucleic acid sequences
    Patent number: 5800994
    Abstract: A new method has been developed for conducting a gene probe assay. The preferred technique involves (1) using a gene amplification technique (e.g., PCR) to multiply the gene sequence of interest and (2) using a hybridization--ligation detection methodology, wherein the sequences of probes hybridized to the target sequence allow for separation and detection (e.g., probes might contain a combination of magnetic particles and acridinium esters) to determine if a specific sequence is present.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: September 1, 1998
    Assignee: Chiron Diagnostics Corporation
    Inventors: Richard A. Martinelli, John C. Arruda