Patents by Inventor John C. Castel

John C. Castel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11020605
    Abstract: Methods are disclosed for reduction of muscle fatigue, enhancement of wound healing and tissue repair and/or reduction of pain. The methods comprise irradiating a muscle or an injured tissue of a subject, as applicable, with pulsed blue and/or red light having an average irradiance that ranges from 0.1 mW/cm2 to 20 mW/cm2 at a radiant exposure that ranges from 0.5 J/cm2 to 60 J/cm2. The pulsed blue and/or red light is preferably applied with a flexible light source that includes a flexible light emitter positioned between a flexible anode and a flexible cathode. The flexible light emitter may comprise a printed LED film or OLEDs that emit blue and/or red light, or a printed LED film or OLEDs that emit blue light in combination with a quantum dot film that converts a portion of the blue light emission into red light.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: June 1, 2021
    Assignee: CAREWEAR CORP.
    Inventor: John C. Castel
  • Patent number: 10981017
    Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. The target is irradiated with pulsed purple or blue light in which (a) the light pulses have a peak irradiance and a pulse duration sufficient to optically excite a photoactive molecule capable of photoeradication of the microorganisms and (b) the light pulses are separated by an off time sufficient to allow the photoactive molecule to return to a ground state creating an oxidation reaction that produces free radicals which destroy a cellular structure of the microorganisms and thereby photoeradicate all or a portion of the microorganisms. The photoactive molecule may comprise either an endogenous molecule present in the microorganisms or an exogenous molecule applied to the target.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: April 20, 2021
    Assignees: SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION, CAREWEAR CORP.
    Inventors: Chukuka S. Enwemeka, John C. Castel
  • Publication number: 20200222718
    Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. The method includes the step of obtaining test data for a plurality of experiments each of which comprises irradiating test microorganisms with a plurality of light pulses having a wavelength that ranges from 380 nm to 500 nm. The light pulses have a plurality of pulse parameters (peak irradiance, pulse duration, and off time between adjacent light pulses) and are provided at a radiant exposure that ranges from 0.5 J/cm2 to 60 J/cm2 during each of a plurality of irradiation sessions. The test data comprises a survival rate for the test microorganisms after irradiation with the light pulses. The method also includes the step of analyzing the test data to identify the pulse parameters for the light pulses and the radiant exposure for each of the irradiation sessions that result in a desired survival rate for the test microorganisms.
    Type: Application
    Filed: March 21, 2020
    Publication date: July 16, 2020
    Inventors: CHUKUKA S. ENWEMEKA, JOHN C. CASTEL
  • Patent number: 10639498
    Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. A light source is configured to irradiate the target with purple or blue light in a pulsed mode of irradiation at an average irradiance that preferably ranges from 0.1 mW/cm2 to 20 mW/cm2. An electronic circuit is configured to control the light source in accordance with an irradiation schedule that includes a plurality of irradiation sessions. The light source is controlled to provide the purple or blue light at a radiant exposure that preferably ranges from 0.5 J/cm2 to 60 J/cm2 during each of the irradiation sessions. The irradiation sessions are provided at a plurality of time intervals so as to cause photoeradication of all or a portion of the microorganisms.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: May 5, 2020
    Assignees: CAREWEAR CORP., SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Chukuka S. Enwemeka, John C. Castel
  • Publication number: 20190366115
    Abstract: Methods are disclosed for reduction of muscle fatigue, enhancement of wound healing and tissue repair and/or reduction of pain. The methods comprise irradiating a muscle or an injured tissue of a subject, as applicable, with pulsed blue and/or red light having an average irradiance that ranges from 0.1 mW/cm2 to 20 mW/cm2 at a radiant exposure that ranges from 0.5 J/cm2 to 60 J/cm2. The pulsed blue and/or red light is preferably applied with a flexible light source that includes a flexible light emitter positioned between a flexible anode and a flexible cathode. The flexible light emitter may comprise a printed LED film or OLEDs that emit blue and/or red light, or a printed LED film or OLEDs that emit blue light in combination with a quantum dot film that converts a portion of the blue light emission into red light.
    Type: Application
    Filed: November 29, 2018
    Publication date: December 5, 2019
    Inventor: JOHN C. CASTEL
  • Publication number: 20190151655
    Abstract: A flexible device having a layered structure for delivering light or ultrasound to a skin surface. The device includes a flexible substrate that supports either a flexible light emitter layer or a flexible ultrasound emitter layer, as well as first and second flexible conductive layers. The device has a surface configured to face the skin surface, wherein (a) the light emitter layer emits pulsed light with an intensity that is substantially constant across the device's surface when driven by a power source connected to the conductive layers to thereby deliver a therapeutically effective dose of pulsed light to the skin surface or (b) the ultrasound emitter layer emits ultrasound with an intensity that is substantially constant across the device's surface when driven by a power source connected to the conductive layers to thereby deliver a therapeutically effective dose of ultrasound to the skin surface.
    Type: Application
    Filed: January 23, 2019
    Publication date: May 23, 2019
    Applicant: CAREWEAR CORP.
    Inventors: MICHAEL R. HALL, JOHN C. CASTEL, DAWN CASTEL
  • Publication number: 20190143140
    Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. The target is irradiated with pulsed purple or blue light in which (a) the light pulses have a peak irradiance and a pulse duration sufficient to optically excite a photoactive molecule capable of photoeradication of the microorganisms and (b) the light pulses are separated by an off time sufficient to allow the photoactive molecule to return to a ground state creating an oxidation reaction that produces free radicals which destroy a cellular structure of the microorganisms and thereby photoeradicate all or a portion of the microorganisms. The photoactive molecule may comprise either an endogenous molecule present in the microorganisms or an exogenous molecule applied to the target.
    Type: Application
    Filed: November 29, 2018
    Publication date: May 16, 2019
    Inventors: CHUKUKA S. ENWEMEKA, JOHN C. CASTEL
  • Publication number: 20180280723
    Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. A light source is configured to irradiate the target with purple or blue light in a pulsed mode of irradiation at an average irradiance that preferably ranges from 0.1 mW/cm2 to 20 mW/cm2. An electronic circuit is configured to control the light source in accordance with an irradiation schedule that includes a plurality of irradiation sessions. The light source is controlled to provide the purple or blue light at a radiant exposure that preferably ranges from 0.5 J/cm2 to 60 J/cm2 during each of the irradiation sessions. The irradiation sessions are provided at a plurality of time intervals so as to cause photoeradication of all or a portion of the microorganisms.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 4, 2018
    Inventors: CHUKUKA S. ENWEMEKA, JOHN C. CASTEL
  • Publication number: 20170100585
    Abstract: A flexible device having a layered structure for delivering electrical stimulation and one or both of light and ultrasound to a skin surface is provided. The device is flexible so as to form a non-planar contact surface against the skin surface, and includes one or both of (a) a flexible light emitter layer positioned between two flexible conductive layers that emits light when driven by a power source and (b) a flexible ultrasound emitter layer positioned between two flexible conductive layers that produces ultrasound when driven by a power source. The device also includes a flexible electrical stimulation layer that functions as an electrode and is configured to provide electrical stimulation when driven by a power source.
    Type: Application
    Filed: December 19, 2016
    Publication date: April 13, 2017
    Applicant: SONOVIA HOLDINGS LLC
    Inventors: MICHAEL R. HALL, JOHN C. CASTEL, DAWN CASTEL
  • Patent number: 9561357
    Abstract: A device for delivering light and ultrasound across a skin surface is provided. The device has a layered structure comprising a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. In one embodiment, the light source comprises an organic light emitting diode or a plurality of printed light emitting diodes and the ultrasonic transducer comprises a piezoelectric coating. The device may be provided with a therapeutic or cosmetic composition to be applied to the skin surface, wherein the light and ultrasound emitted from the device cause transdermal transport of the composition through the skin surface.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 7, 2017
    Assignee: SONOVIA HOLDINGS LLC
    Inventors: Michael R. Hall, John C. Castel, Dawn Castel
  • Patent number: 9061128
    Abstract: A system for delivering light and/or ultrasound across a skin surface is provided. The system includes a device having a layered structure comprising one or both of a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. The system also includes one or more sensors in contact with the skin surface and a controller electrically coupled to the device and the sensor. The controller is operable to receive sensor data from the sensor and dynamically control the device in response to the received sensor data.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 23, 2015
    Assignee: SONOVIA HOLDINGS LLC
    Inventors: Michael R. Hall, John C. Castel, Dawn Castel
  • Patent number: 8881894
    Abstract: A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: November 11, 2014
    Assignee: Sonovia Holdings LLC
    Inventors: John C. Castel, R. Patrick Abergel
  • Publication number: 20140276247
    Abstract: A device for delivering light and ultrasound across a skin surface is provided. The device has a layered structure comprising a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. In one embodiment, the light source comprises an organic light emitting diode or a plurality of printed light emitting diodes and the ultrasonic transducer comprises a piezoelectric coating. The device may be provided with a therapeutic or cosmetic composition to be applied to the skin surface, wherein the light and ultrasound emitted from the device cause transdermal transport of the composition through the skin surface.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: SONOVIA HOLDINGS LLC
    Inventors: MICHAEL R. HALL, John C. Castel, Dawn Castel
  • Publication number: 20140276248
    Abstract: A system for delivering light and/or ultrasound across a skin surface is provided. The system includes a device having a layered structure comprising one or both of a light source and an ultrasonic transducer. The light source comprises a flexible light emitter layer electrically coupled to a first conductive layer and a second conductive layer, wherein at least one of the first and second conductive layers is transparent. The ultrasonic transducer comprises a flexible ultrasound emitter layer electrically coupled to a third conductive layer and a fourth conductive layer. The system also includes one or more sensors in contact with the skin surface and a controller electrically coupled to the device and the sensor. The controller is operable to receive sensor data from the sensor and dynamically control the device in response to the received sensor data.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: SONOVIA HOLDINGS LLC
    Inventors: Michael R. HALL, John C. CASTEL, Dawn CASTEL
  • Patent number: 8491212
    Abstract: A multifunctional multi-compartment applicator for the stable storage of solid ascorbic acid and topical application of ascorbic acid in solution to the skin, the applicator having an absorbent end and an abrasive end.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: July 23, 2013
    Assignee: Laboratoire Naturel Paris, LLC
    Inventors: John C. Castel, R. Patrick Abergel
  • Publication number: 20100047326
    Abstract: A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.
    Type: Application
    Filed: August 21, 2008
    Publication date: February 25, 2010
    Inventors: John C. Castel, R. Patrick Abergel
  • Publication number: 20090232580
    Abstract: A multifunctional multi-compartment applicator for the stable storage of solid ascorbic acid and topical application of ascorbic acid in solution to the skin, the applicator having an absorbent end and an abrasive end.
    Type: Application
    Filed: March 17, 2008
    Publication date: September 17, 2009
    Inventors: John C. Castel, R. Patrick Abergel
  • Patent number: 6068606
    Abstract: A back support brace for supporting the back of a wearer of the brace for preventing injuries and reinforcing proper lifting mechanics during lifting activities comprises a back panel, a left side panel and a right side panel wherein the left and right side panels are secured at opposite ends of the back panel and are wrappable around the waist of a wearer and adjustably securable thereto. Aligned pairs of belt loops are provided on an inner surface of the brace and are adapted to receive a belt for holding up the pants of the wearer of the brace therethrough so as to prevent the brace from being advanced out of a preset position during lifting activities. A lower edge of the brace includes cutout portions generally positioned above the thighs of the wearer such that the lower edge is contoured to conform to the shape of the wearer throughout lifting activities. Elastic insets extend over the cutout portions to increase tension across the back panel.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: May 30, 2000
    Assignee: The Smith Truss Company
    Inventors: John C. Castel, Dawn S. Castel, Michael R. Hall
  • Patent number: 5413550
    Abstract: An ultrasound therapy system with automatic dose control includes an ultrasound transducer, an ultrasound generator controllable in frequency and power output connected to the transducer, a system controller interfaced to the generator, input switches interfaced to the controller to enable the input of selected ultrasound treatment parameters, and a display interfaced to the controller. The controller is programmed to calculate an ultrasound treatment dosage in terms of frequency, ultrasound intensity, and treatment time from the entered treatment parameters. Once treatment is started, the controller tracks the accumulated dosage applied to the tissue. The clinician can vary the intensity or treatment time, and the controller will recalculate the other factor for the remaining portion of the unapplied treatment dosage.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: May 9, 1995
    Assignee: PTI, Inc.
    Inventor: John C. Castel
  • Patent number: 5188586
    Abstract: A back support brace for supporting the back of a wearer of the brace for preventing injuries and reinforcing proper lifting mechanics during lifting activities comprises a back panel, a left side panel and a right side panel wherein the left and right side panels are secured at opposite ends of the back panel and are wrappable around the waist of a wearer and adjustably securable thereto. Aligned pairs of belt loops are provided on an inner surface of the brace and are adapted to receive a belt for holding up the pants of the wearer of the brace therethrough so as to prevent the brace from being advanced out of a preset position during lifting activities. A lower edge of the brace includes cutout portions generally positioned above the thighs of the wearer such that the lower edge is contoured to conform to the shape of the wearer throughout lifting activities. Elastic insets extend over the cutout portions to increase tension across the back panel.
    Type: Grant
    Filed: October 4, 1991
    Date of Patent: February 23, 1993
    Assignee: The Smith Truss Company
    Inventors: John C. Castel, Dawn S. Castel, Michael R. Hall