Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

Abstract: An auto-injector includes a front housing carrying a syringe and an activation cap covering a needle of the syringe, and a rear housing including a drive assembly for automatically deliver agent(s) from the syringe when the device is activated. The rear housing includes a gas canister and an opener mechanism for opening the canister into a set of chambers of an inner housing within the outer housing. When a contact surface of the activation cap is pressed against a subject's skin to insert the needle, the activation cap retracts into the outer housing and activates the opener mechanism to release pressurized gas from the canister into the chambers to advance a plunger within the inner housing to deliver the agent(s) from the syringe into the subject. After the injection is completed and the device is withdrawn away from the skin, the activation cap automatically advances to cover the needle.

Abstract: Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

Abstract: A system and method for detecting and/or capturing a cassette is disclosed. The cassette capture mechanism may be used with a surgical console of a surgical system, wherein the system has a cassette receiving area having at least two alignment sensors and a plurality of capture plungers; and at least two capture hooks which may engage with a cassette, wherein at least one of the at least two alignment sensors produces a signal indicative of the presence of a cassette.

Abstract: A system for a surgical system is disclosed, comprising a surgical cassette, comprising a cassette for use with a surgical console, further comprising a first set of fluid channels having a first set of ports, a second set of fluid channels having a second set of ports, at least one rotary valve in fluid communication with the first set of fluid channels, at least one rotary valve in fluid communication with the second set of fluid channels, and a plurality of deformable channels, wherein the deformable channels are fluidly connected to ones of the first set of ports and second set of ports.

Abstract: A system for a surgical system is disclosed, comprising a system for distributing fluid in a surgical cassette, comprising a first pump head operable by a first drive shaft and a second pump head operable by a second drive shaft, wherein the second drive shaft is at least partially enclosed by the first drive shaft.

Abstract: A system for a surgical system is disclosed, comprising system for distributing fluid in a surgical cassette, comprising at least one at least partially deformable bladder at least partially disposed on at least one rigid surface, wherein the bladder forms a portion of a channel, at least a first and second port in fluid communication with the channel, wherein the channel comprises at least two portions having a substantially uniform first dimension separated by a second portion have a second dimension, and wherein at least two pump head rollers are engaged with the bladder.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

Abstract: An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis forward of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels. In various instances the prime mover is mounted to the chassis such that it has a longitudinal orientation relative to a longitudinal axis of the vehicle. Additionally, in various instances wherein the torque transfer device is a transmission, the transmission is mounted such that it has a longitudinal orientation relative to the longitudinal axis of the vehicle.

Abstract: An apparatus may comprise an outer skin having an exterior side and an interior side, an internal structure positioned relative to the interior side of the outer skin, and an inner skin. The internal structure may be capable of absorbing a blast load applied to the exterior side of the outer skin. The internal structure may be located between the outer skin and the inner skin.

Abstract: A ground vehicle and a method for articulating a payload module for mobility assist are disclosed. The ground vehicle comprises a chassis; and a payload module capable of articulating relative to the chassis to assist the mobility of the ground vehicle. The method comprises articulating a payload module relative to a chassis.

Abstract: An apparatus may comprise an outer skin having an exterior side and an interior side, an internal structure positioned relative to the interior side of the outer skin, and an inner skin. The internal structure may be capable of absorbing a blast load applied to the exterior side of the outer skin. The internal structure may be located between the outer skin and the inner skin.

Abstract: A hub drive includes an in-hub motor and a shifting in-hub transmission coupled with the motor. A hub drive wheel assembly includes a wheel comprising a hub, an in-hub motor, and a shifting in-hub transmission having an input attached to the motor and an output attached to the wheel. A vehicle includes a chassis, a wheel comprising a hub, an in-hub motor, and a shifting in-hub transmission having an input attached to the motor and an output attached to the wheel for rotating the wheel with respect to the chassis. A method includes providing a shifting transmission and a motor coupled with the transmission in a hub of a wheel, providing electrical power to the motor, and rotating the motor with the electrical power. The method further includes rotating the transmission with the motor and rotating the wheel with the transmission.

Abstract: An all terrain vehicle has a frame carried by a group of wheels. At least one of the wheels is steerably connected to the frame. A steering handle assembly is rotatably connected to the frame. A servo valve has an input shaft connected to the steering handle assembly and an output shaft connected to a pitman arm. A linkage extends from the pitman arm to the steerable wheel or wheels. A pump draws fluid from a reservoir and passes the fluid through the servo valve before the fluid is returned to the reservoir. The servo valve redirects at least a portion of the flow to a cylinder to drive a ram within the cylinder in response to steering movement of the steering handle assembly. The ram, in turn, provides a power assist to the steerable wheel or wheels. A variable speed, constant displacement pump can be used to vary the flow rate in a manner that reduces the flow rate as the vehicle speed increases. Alternatively, a bypass can be used to vary a flow rate through the servo valve.