Patents by Inventor John C. Dykstra

John C. Dykstra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENISTEIN TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISORDERS
    Publication number: 20240058299
    Abstract: Methods and materials and methods for reducing organ and tissue damage associated with inflammatory and immunological disorders are provided herein. For example, this document provides methods and materials for using genistein to treat respiratory distress syndrome or acute lung injury (e.g., pneumonitis, pulmonary fibrosis, dyspnea, pneumonia, and/or pulmonary edema resulting from viral infection, allergic responses, chemical insults, radiation, tissue injury, persistent infections, or autoimmune reactions).
    Type: Application
    Filed: January 11, 2022
    Publication date: February 22, 2024
    Inventors: Artur A. Serebrenik, Michael D. Kaytor, John C. Dykstra, Ronald J. Zenk, Brett D. Anderson
  • GENISTEIN TREATMENT OF INFLAMMATORY PULMONARY INJURY
    Publication number: 20230143352
    Abstract: Materials and methods for using genistein to treat respiratory distress syndrome or acute lung injury (e.g., pneumonitis, pulmonary fibrosis, dyspnea, pneumonia, and/or pulmonary edema resulting from viral infection, including SARS-CoV-2 infection) are provided herein.
    Type: Application
    Filed: April 6, 2021
    Publication date: May 11, 2023
    Inventors: Artur A. Serebrenik, Michael D. Kaytor, John C. Dykstra, Ronald J. Zenk
  • PROTECTING TISSUE AND MITIGATING INJURY FROM RADIATION-INDUCED IONIZING EVENTS
    Publication number: 20220401375
    Abstract: Materials and methods for reducing, preventing, or mitigating the effects of exposure to ionizing radiation are provided herein.
    Type: Application
    Filed: August 18, 2022
    Publication date: December 22, 2022
    Inventors: Adam J. Harvey, Michael D. Kaytor, John C. Dykstra
  • SOLID DISPERSION GENISTEIN COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220273573
    Abstract: The present invention is directed to solid dispersion formulations comprising genistein and one or more pharmaceutically acceptable excipients. In particular embodiments, the one or more pharmaceutically acceptable excipients include polyvinylpyrrolidone. Various techniques can be used to form the solid dispersions, including spray drying and extrusion techniques.
    Type: Application
    Filed: May 18, 2022
    Publication date: September 1, 2022
    Inventors: Michael D. Kaytor, Adam J. Harvey, John C. Dykstra, Samuel Elliott Kennedy, April Naab, Michael Edward Grass
  • Protecting tissue and mitigating injury from radiation-induced ionizing events
    Patent number: 11419827
    Abstract: Materials and methods for reducing, preventing, or mitigating the effects of exposure to ionizing radiation are provided herein. In general, the methods can include administering a nanoparticulate genistein composition to a subject identified as having been exposed or at risk of being exposed to ionizing radiation, such as proton radiation.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: August 23, 2022
    Assignee: Humanetics Corporation
    Inventors: Adam J. Harvey, Michael D. Kaytor, John C. Dykstra
  • PROTECTING TISSUE AND MITIGATING INJURY FROM RADIATION-INDUCED IONIZING EVENTS
    Publication number: 20190380972
    Abstract: Materials and methods for reducing, preventing, or mitigating the effects of exposure to ionizing radiation are provided herein.
    Type: Application
    Filed: February 23, 2018
    Publication date: December 19, 2019
    Inventors: Adam J. Harvey, Michael D. Kaytor, John C. Dykstra
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 10314812
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: June 11, 2019
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
    Publication number: 20190038593
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Application
    Filed: February 28, 2018
    Publication date: February 7, 2019
    Applicant: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 9937148
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: April 10, 2018
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
    Publication number: 20180000773
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Application
    Filed: September 1, 2017
    Publication date: January 4, 2018
    Applicant: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 9782384
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: October 10, 2017
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • PREDICTING AND REDUCING COGNITIVE DECLINE BASED ON GSK-3 LEVELS
    Publication number: 20170102398
    Abstract: Materials and methods for predicting cognitive decline based on total or active/inactive levels of markers such as GSK-3 are provided. Materials and methods for preventing or delaying the onset of cognitive decline in individuals identified as being in need thereof also are provided.
    Type: Application
    Filed: March 5, 2015
    Publication date: April 13, 2017
    Inventors: Michael D. KAYTOR, John C. DYKSTRA
  • PROTECTING TISSUE AND MITIGATING INJURY FROM CHEMICAL EXPOSURE
    Publication number: 20170000761
    Abstract: Materials and methods for reducing, preventing, or mitigating the effects of exposure to toxic chemical agents.
    Type: Application
    Filed: November 26, 2014
    Publication date: January 5, 2017
    Inventors: Michael D. Kaytor, John C. Dykstra
  • SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
    Publication number: 20160279093
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Application
    Filed: June 3, 2016
    Publication date: September 29, 2016
    Applicant: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 9387171
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: July 12, 2016
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
    Publication number: 20150272887
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Applicant: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
    Patent number: 9084726
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: July 21, 2015
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
    Publication number: 20150147359
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Application
    Filed: November 26, 2013
    Publication date: May 28, 2015
    Applicant: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Combination of pinitol and creatine to enhance uptake and retention of creatine
    Publication number: 20030212134
    Abstract: Muscle performance can be improved and muscle hypertrophy enhanced, through enhanced uptake and retention of creatine resulting in improved ATP resynthesis, by administering an effective synergistic amount of a combination of creatine or an active derivative thereof and pinitol or an active derivative or metabolite thereof.
    Type: Application
    Filed: September 30, 2002
    Publication date: November 13, 2003
    Inventor: John C. Dykstra
  • Treatment of dermatitis by the topical application of &Dgr;5-androstene-3&bgr;-ol-7,17 dione and metabolizable precursors thereof
    Patent number: 6465446
    Abstract: Dermatitis can be treated by the administration of &Dgr;5-androstene-3&bgr;-ol-7,17 dione and metabolizable precursors thereof, such as &Dgr;5-androstene-3&bgr;-acetoxy-7,17 dione, to the skin.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: October 15, 2002
    Inventor: John C. Dykstra