Patents by Inventor John C. Prostko

John C. Prostko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETERMINING SARS-COV-2 ANTIGEN AND ANTI-SARS-COV-2 ANTIBODY IN A SAMPLE
    Publication number: 20240069037
    Abstract: Disclosed herein are methods, kits, and systems for detecting at least one type of SARS-CoV-2 antigen and at least one type of anti-SARS-CoV-2 antibody in a subject, which comprises the use of at least two different types of microparticle reagents for binding at least one type of SARS-CoV-2 antigen and at least one type of anti-SARS-CoV-2 antibody and at least two different types of detection reagents for binding each of the microparticle reagents.
    Type: Application
    Filed: June 30, 2023
    Publication date: February 29, 2024
    Inventors: David J. Daghfal, John C. Prostko
  • METHODS AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF AN ANTI-B-CORONAVIRUS ANTIBODY IN A SAMPLE
    Publication number: 20230258638
    Abstract: Disclosed herein are methods, kits, systems, algorithms and improvements for detecting the presence of or determining an amount, quantity, concentration and/or level of an antibody against at least one type of ?-coronavirus, such as, for example, an antibody against SARS-CoV or SARS-CoV-2, in one or more samples obtained from a subject. In some aspects, the methods, kits and systems relate to detecting the presence of or determining an amount, quantity, concentration and/or level of at least one type of anti-?-coronavirus antibody, such as an IgG and/or IgM antibody, in one or more samples obtained from a subject.
    Type: Application
    Filed: October 12, 2022
    Publication date: August 17, 2023
    Inventors: A. Scott Muerhoff, John C. Prostko, James L. Stewart, Mary A. RODGERS, Gavin A. CLOHERTY, James Hartnett, Jeff Moore, Kathy Otis, Alak Kar, Bailin Tu, Bryan Tieman, Carolyn Strobel, David Hawksworth, Robert Ziemann, Zhihong Lin, Chris Marohnic, Peter Wiebe, Todd Meyer, Weijie Jiao, Gangamani S. Beligere, Saminathan X. Muthusamy, Jessica L. Grieshaber, Sandra K. Pearce, Edwin C. Frias, Russell E. Taylor, Kelly Coller, Yangrong E. Zhang, Thomas T. Biegalski, David J. Daghfal, Claudio Galli, Sergey Y. Tetin, Qiaoqiao Ruan, Patrick MacDonald, Michael S. Cassidy, Mary E. Gardiner, Mary Ann P. Palafox, Matthew S. Matias, Melissa B. Brennan, Philip W. Schultz, Beth C. Trudeau
  • Subject anti-HCV antibody detection assays employing NS3 capture peptides
    Patent number: 11340230
    Abstract: The present disclosure provides methods, kits, and compositions for detecting subject anti-HCV antibodies in a sample using NS3 capture peptides. In certain embodiments, at least two NS3 helicase (NS3h) capture peptides and at least two conjugate peptides (e.g., NS3h conjugate peptides) are employed together, which allows for a broad dynamic range of subject antibody detection in a one-step type assay. In other embodiments, methods are provided of detecting NS3-specific subject antibodies without the use of a reducing agent. In some embodiments, NS3-specific subject antibodies are detected with a ‘double shot’ of NS3 conjugate peptide (e.g., conjugate peptide added to a sample both before and after washing).
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: May 24, 2022
    Assignee: Abbott Laboratories
    Inventors: Anthony S. Muerhoff, John C. Prostko, Christopher C. Marohnic
  • SUBJECT ANTI-HCV ANTIBODY DETECTION ASSAYS EMPLOYING NS3 CAPTURE PEPTIDES
    Publication number: 20210041442
    Abstract: The present disclosure provides methods, kits, and compositions for detecting subject anti-HCV antibodies in a sample using NS3 capture peptides. In certain embodiments, at least two NS3 helicase (NS3h) capture peptides and at least two conjugate peptides (e.g., NS3h conjugate peptides) are employed together, which allows for a broad dynamic range of subject antibody detection in a one-step type assay. In other embodiments, methods are provided of detecting NS3-specific subject antibodies without the use of a reducing agent. In some embodiments, NS3-specific subject antibodies are detected with a ‘double shot’ of NS3 conjugate peptide (e.g., conjugate peptide added to a sample both before and after washing).
    Type: Application
    Filed: October 15, 2020
    Publication date: February 11, 2021
    Inventors: Anthony S. Muerhoff, John C. Prostko, Christopher C. Marohnic
  • Subject anti-HCV antibody detection assays employing NS3 capture peptides
    Patent number: 10816551
    Abstract: The present disclosure provides methods, kits, and compositions for detecting subject anti-HCV antibodies in a sample using NS3 capture peptides. In certain embodiments, at least two NS3 helicase (NS3h) capture peptides and at least two conjugate peptides (e.g., NS3h conjugate peptides) are employed together, which allows for a broad dynamic range of subject antibody detection in a one-step type assay. In other embodiments, methods are provided of detecting NS3-specific subject antibodies without the use of a reducing agent. In some embodiments, NS3-specific subject antibodies are detected with a ‘double shot’ of NS3 conjugate peptide (e.g., conjugate peptide added to a sample both before and after washing).
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: October 27, 2020
    Assignee: Abbott Laboratories
    Inventors: Anthony S. Muerhoff, John C. Prostko, Christopher C. Marohnic
  • SUBJECT ANTI-HCV ANTIBODY DETECTION ASSAYS EMPLOYING NS3 CAPTURE PEPTIDES
    Publication number: 20190064169
    Abstract: The present disclosure provides methods, kits, and compositions for detecting subject anti-HCV antibodies in a sample using NS3 capture peptides. In certain embodiments, at least two NS3 helicase (NS3h) capture peptides and at least two conjugate peptides (e.g., NS3h conjugate peptides) are employed together, which allows for a broad dynamic range of subject antibody detection in a one-step type assay. In other embodiments, methods are provided of detecting NS3-specific subject antibodies without the use of a reducing agent. In some embodiments, NS3-specific subject antibodies are detected with a ‘double shot’ of NS3 conjugate peptide (e.g., conjugate peptide added to a sample both before and after washing).
    Type: Application
    Filed: September 5, 2018
    Publication date: February 28, 2019
    Inventors: Anthony S. Muerhoff, John C. Prostko, Christopher C. Marohnic