Patents by Inventor John C. Ruddock

John C. Ruddock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polycyclic ether antibiotic
    Patent number: 5100785
    Abstract: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in swine and ruminants. Two minor components, wherein R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
    Type: Grant
    Filed: December 17, 1990
    Date of Patent: March 31, 1992
    Assignee: Pfizer Inc.
    Inventors: Walter P. Cullen, Hiroshi Maeda, John C. Ruddock, Junsuke Tone
  • Fermentation process for glycopeptide antibiotic
    Patent number: 4992369
    Abstract: A new glycopeptide antibiotic UK-68,597 can be prepared by submerged aerobic propagation in aqueous nutrient media of Actinoplanes sp. ATCC 53533. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in poultry, swine and ruminants.
    Type: Grant
    Filed: June 15, 1989
    Date of Patent: February 12, 1991
    Assignee: Pfizer Inc.
    Inventors: Hiroshi Maeda, Junsuke Tone, John C. Ruddock, Kelvin S. Holdom
  • Polycyclic ether antibiotics
    Patent number: 4992423
    Abstract: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization is swine and ruminants. Two minor components, where R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
    Type: Grant
    Filed: February 8, 1988
    Date of Patent: February 12, 1991
    Assignee: Pfizer Inc.
    Inventors: Walter P. Cullen, Hiroshi Maeda, John C. Ruddock, Junsuke Tone
  • New glycopeptide antibiotic
    Patent number: 4954482
    Abstract: A new glycopeptide antibiotic UK-68,597 can be prepared by submerged aerobic propagation in aqueous nutrient media of Actinoplanes sp. ATCC 53533. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in poultry, swine and ruminants.
    Type: Grant
    Filed: July 20, 1989
    Date of Patent: September 4, 1990
    Assignee: Pfizer Inc.
    Inventors: Hiroshi Maeda, Junsuke Tone, John C. Ruddock, Kelvin S. Holdom
  • Antibiotic produced by fermentation
    Patent number: 4920215
    Abstract: The antibiotic of the formula: ##STR1## wherein R is ##STR2## The antibiotic is useful for the treatment of swine dysentery and for promoting growth and/or increasing the efficiency of food utilization in poultry, swine and ruminants.
    Type: Grant
    Filed: December 16, 1987
    Date of Patent: April 24, 1990
    Assignee: Pfizer Inc.
    Inventors: Kelvin S. Holdom, John C. Ruddock, Junsuke Tone, Hiroshi Maeda, Martin R. Jefson
  • Polycyclic ether antibiotic
    Patent number: 4746650
    Abstract: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in swine and ruminants. Two minor components, wherein R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
    Type: Grant
    Filed: June 21, 1985
    Date of Patent: May 24, 1988
    Assignee: Pfizer Inc.
    Inventors: Walter P. Cullen, Hiroshi Maeda, John C. Ruddock, Junsuke Tone
  • 19-epi-dianemycin as an anticoccidial and antibacterial agent
    Patent number: 4707493
    Abstract: Antibiotic 19-epi-dianemycin, process for its preparation by fermenting a new strain of Streptomyces hygroscopicus, and isolation from the fermentation broth; and its use as an anticoccidial agent and antibacterial agent against gram-positive bacteria.
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: November 17, 1987
    Assignee: Pfizer Inc.
    Inventors: Walter D. Celmer, Walter P. Cullen, Hiroshi Maeda, John C. Ruddock, Junsuke Tone