Patents by Inventor John C. Tomesch

John C. Tomesch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of monoalkylcarbamate group-containing compounds
    Patent number: 4868319
    Abstract: An improved process for preparing monoalkylcarbamate group-containing compounds comprising reacting a hydroxy group-containing compound with an organic halide and an alkali metal cyanate in the conjoint presence of a phase transfer catalyst and a solvent.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: September 19, 1989
    Assignee: Sandoz Pharm. Corp.
    Inventors: John C. Tomesch, Mahavir Prashad, William J. Houlihan
  • N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts and use thereof in PAF inhibition
    Patent number: 4820718
    Abstract: The invention discloses certain N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts useful as PAF inhibitors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-induced blood platelet aggregation, PAF-mediated bronchoconstriction and extravasation, PAF-induced hypotension, PAF-induced ischemic bowel disease and PAF-mediated, endotoxin-induced lung injury.
    Type: Grant
    Filed: September 17, 1987
    Date of Patent: April 11, 1989
    Assignee: Sandoz Pharm. Corp.
    Inventor: John C. Tomesch
  • Tropyl derivatives
    Patent number: 4366154
    Abstract: Tropyl derivatives of the formula: ##STR1## in which R.sup.1 is (a) phenyl linked through a direct bond, --O--, ##STR2## (in which m=2 or 3); (b) diphenylmethyl; or (c) 10H-phenothiazin-10-yl; (each of which type may be substituted, or unsubstituted); R.sup.2 is --H, --OH, or --O Si (CH.sub.3).sub.3 ; and R.sup.3 is substituted or unsubstituted phenyl, e.g. 4-[3-(4-fluorobenzoyl)-8-azabicyclo [3.2.1]oct-8-yl]-1-(-4-fluorophenyl)-1-butanone, in free base form or pharmaceutically acceptable acid addition salts are useful as pharmaceuticals.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: December 28, 1982
    Assignee: Sandoz, Inc.
    Inventor: John C. Tomesch