Patents by Inventor John C. Yu

John C. Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo animal model of human leukemia
    Patent number: 6930222
    Abstract: The present invention provides a process for making an in vivo model of human leukemia. The process includes the steps of: pre-conditioning an immunodeficient rodent by administering to the rodent a sub-lethal dose of irradiation and injecting the rodent with an effective pre-conditioning amount of human fetal cord blood mononuclear cells; maintaining the rodent for from about 5 to 10 days; and injecting the rodent with an effective engrafting amount of primary human leukemia cells. An in vivo and in vitro model of human leukemia are also provided.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: August 16, 2005
    Assignee: The Scripps Research Institute
    Inventor: John C. Yu
  • In vivo animal model of human leukemia
    Publication number: 20020046411
    Abstract: The present invention provides a process for making an in vivo model of human leukemia. The process includes the steps of: pre-conditioning an immunodeficient rodent by administering to the rodent a sub-lethal dose of irradiation and injecting the rodent with an effective pre-conditioning amount of human fetal cord blood mononuclear cells; maintaining the rodent for from about 5 to 10 days; and injecting the rodent with an effective engrafting amount of primary human leukemia cells. An in vivo and in vitro model of human leukemia are also provided.
    Type: Application
    Filed: August 22, 2001
    Publication date: April 18, 2002
    Applicant: The Scripps Research Institute
    Inventor: John C. Yu