Abstract: The invention populates UI terms referenced in help files of a software program with the corresponding UI terms used in the user interface controls of the software program during execution of the software program. The UI terms referenced in the help files are uniquely identified. A repository is built that contains information identifying the UI terms referenced in the help files and their corresponding UI terms in the user interfaces of the software program. A software component is provided that is capable of runtime population of the UI terms referenced in the help files with their corresponding UI terms in the user interfaces of the software program, using information stored in the repository.

Abstract: The complete DNA sequence of the gene cluster encoding the polypeptides responsible for the biosynthesis of the polyene antibiotic amphotericin of S. nodosus is provided. Engineered alteration of the amphC) gene so as to eliminate production of amphotericin A in favour of the more active form amphotericin B. as well as the production of amphotericin analogues having altered characteristics, is enabled by manipulation of the sequences of the cluster.