Abstract: Systems and methods for non-invasively assessing ciliary muscle accommodative potential in phakic eyes may include receiving a plurality of signals generated by a plurality of bipolar electrodes during a ciliary muscle assessment procedure, each of the plurality of signals indicating an electrical field associated with a patient's ciliary muscle, and analyzing the signals to evaluate the patient's ciliary muscle accommodative potential.

Abstract: Disclosed herein is an implantable accommodative IOL system for insertion into an eye of a patient, the system comprising: an optical element and a housing including an opaque frame. The optical element comprises an optical lens having variable optical power, and the opaque frame is circumferentially disposed around a periphery of the optical element.

Abstract: Systems and methods for non-invasively assessing ciliary muscle accommodative potential in phakic eyes may include receiving a plurality of signals generated by a plurality of bipolar electrodes during a ciliary muscle assessment procedure, each of the plurality of signals indicating an electrical field associated with a patient's ciliary muscle, and analyzing the signals to evaluate the patient's ciliary muscle accommodative potential.

Abstract: Disclosed herein is an implantable accommodative IOL system for insertion into an eye of a patient, the system comprising: an optical element and a housing including an opaque frame. The optical element comprises an optical lens having variable optical power, and the opaque frame is circumferentially disposed around a periphery of the optical element.

Abstract: Disclosed herein is an implantable accommodative IOL device for insertion into an eye of a patient, comprising an active region and a passive region. The active region has a first thickness and first refractive index, and the active region comprises an electrically responsive optical lens having variable optical power. The passive region is disposed at a periphery of the active region, and the passive region has a second thickness and a second refractive index. The second refractive index is different than the first refractive index. Thus, the light beams passing through the active and passive regions have a phase difference, thereby providing an extended depth of field.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: A system for determining an accommodative force in a patient includes a sensor adapted to detect motion of a lens of the patient relative to a globe of the patient's eye, a controller configured to determine an accommodative force in the patient based on the relative motion and to determine at least one parameter for an intraocular lens based on the accommodative force, and an interface adapted to output the at least one parameter for the intraocular lens.

Abstract: A system for determining an accommodative force in a patient includes a sensor adapted to detect motion of a lens of the patient relative to a globe of the patient's eye, a controller configured to determine an accommodative force in the patient based on the relative motion and to determine at least one parameter for an intraocular lens based on the accommodative force, and an interface adapted to output the at least one parameter for the intraocular lens.

Abstract: A system and method for determining an optimal position of an eye relative to an ophthalmic device are disclosed. One embodiment of the method includes receiving data comprising an image of a surface of an eye with the eye at a first position relative to an ophthalmic device. An edge feature in the image is located, and a sharpness calculation on the edge feature is performed using a predetermined algorithm to yield a sharpness value. The eye surface is then adjusted to a second position relative to the ophthalmic device, and the previous steps are repeated until the sharpness value is maximized, which is an indication that an optimal eye position has been achieved. An embodiment of the system includes a processor and a software package executable by the processor, the software package adapted to perform the calculations as above. Means are also provided for adjusting the eye surface to a second position relative to the ophthalmic device.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a conical flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: A method for performing wavefront-guided laser surgery on a cornea includes the step of calculating a corneal flap configuration based upon collected anatomical information on an eye and wavefront data on a cornea of the eye. Such data may be collected by, for example, an aberrometer, although this is not intended as a limitation. The calculated configuration is transmitted to a processor in controlling relation to a corneal flap-cutting device. The flap-cutting device is used to create a corneal flap based upon the calculated configuration. A system for performing wavefront-guided laser surgery on a cornea includes a processor for receiving the anatomical information and wavefront data. A software package is adapted to calculate the corneal flap configuration and to control a corneal flap-cutting device to cut a corneal flap commensurate with the calculated corneal flap configuration.

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription.

Abstract: An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.

Abstract: An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.

Abstract: A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.

Abstract: An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.

Abstract: A system or method of positioning an ophthalmic device relative to an eye is provided. The method first obtains a series of images of an eye. In these series of images, the distance between the ophthalmic device and the eye is varied while the region of the eye image remains substantially the same. It is possible then to process these images to determine the high frequency content associated with each image. By comparing the high frequency content associated with each image, it is possible to determine which image has the largest amount of high frequency content. The high frequency content is maximized when the image is the sharpest. An optimally focused image will have the largest amount of high frequency content. By examining the high frequency content associate with the series of images is impossible to adjust the relative position and distance between the eye and the ophthalmic device to the distance associated with the image having the largest amount of high frequency content (i.e., optimally focused).

Abstract: A method for optimizing a prescription for laser-ablation corneal treatment includes receiving a measured correction prescription for a current patient. Next a database of treatment outcomes on a plurality of previously treated patients is accessed. The database contains a desired correction, and an actual correction. A difference between the desired correction and the actual correction represents an over- or undercorrection resulting from surgery. From the difference data is calculated a distribution of data points as a function of correction level. From the data-point distribution is calculated a statistically based offset applicable to the correction prescription for matching actual corrections with desired corrections. From the data-point distribution is calculated a confidence interval of the data using a predetermined confidence level. The statistically based offset is then adjusted based upon the confidence interval to provide an optimized prescription.

Abstract: A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.

Abstract: An illumination system and method of illuminating a surgical site are disclosed. One embodiment of the illumination system comprises: a composite illumination source, comprising a plurality of light sources operable to emit a plurality of collinear light beams; and an illumination lens, operable to receive and focus the plurality of light beams at a focal plane; wherein the plurality of collinear light beams are directed onto an off-axis portion of the illumination lens and wherein the illumination lens is aligned co-axially and confocally with an objective lens of an observation device. The light sources can be solid-state lighting devices, such as light-emitting diodes. The observation device can be a surgical ophthalmic microscope. The illumination lens can have a larger diameter than the objective lens, and the off-axis portion of the illumination lens can comprise a Fresnel type lens.