Abstract: An optical network unit may include a light sensitive unit suitable for receiving NRZ and/or PAM signals effectively. The optical network unit may include a laser transmission unit for providing NRZ and/or PAM signals effectively.

Abstract: A system to study various forces acting on an athletic field or an athletic surface caused by the interaction between a shoe and the turf or athletic surface during a simulated impact includes a cart slidably affixed to a rail, an actuator linked to the cart, and a footform affixed to the cart. The footform is configured to mimic a human foot, animal hoof or animal foot. The cart, rail and actuator are arranged to move the cart and attached footform at an angle relative to a substantially horizontal surface to be tested, whereby the footform contacts the surface to be tested at a selected contact angle.

Abstract: An aircraft with an engine support structure, the aircraft including at least an engine wherein the at least engine is top mounted to an aircraft, a main body, and an engine support structure including a plurality of hoop structures, wherein at least one horseshoe structure is located forward of the center of gravity to the at least engine.

Abstract: A dispensing system for a floor treatment composition. The dispensing system includes a housing partially enclosing a cavity and a cradle moveable within the housing along a z-axis from a first position to a second position. The dispensing system further includes a chassis and a sliding lock that includes an open frame. An inlet canula projects through the open frame. When the cradle is in the second position, the inlet canula entrance projects through the open frame and through a liquid transport aperture in the cradle. Latches extending from the open frame also project through engagement apertures in the cradle when the cradle is in the second position. The dispensing system further includes a pump in fluid communication with the inlet canula and a mop head in fluid communication with the pump.

Abstract: Provided are a storage device, system, and method for performance enhancing measures for storage in which high-performance volumes reside. Indication is made of a volume configured in the arrays to have high-performance. An array is determined storing the indicated volume. A determination is made of storage devices in which the determined array resides. The storage devices are enabled to perform garbage collection on blocks of data having valid and invalid pages in the storage devices at a first garbage collection rate and a second garbage collection rate. The second garbage collection rate causes a storage device to perform garbage collection with respect to a greater number of blocks than the first garbage collection rate. A command is sent to the determined storage devices to garbage collect at the second garbage collection rate.

Abstract: Low profile continuous analyte measurement systems and systems and methods for implantation within the skin of a patient are provided.

Abstract: Rotary positive displacement machines can include a rotor having a teardrop-shaped profile that undergoes planetary motion relative to a stator having an elliptical or near-elliptical profile. In some embodiments, these rotary positive displacement machines can be used for a variety of applications including as positive displacement pumps. In some embodiments the rotor and stator are helical. In some embodiments the rotor comprises a dynamic seal. Aspects of the machine geometry can be selected to provide operational and/or durability benefits.

Abstract: Described herein is a composition comprising a unique and novel combination of natural ingredients supporting cardiovascular health by contributing to healthy serum cholesterol levels while also reducing CRP and IL-6 cytokine levels. Furthermore, the composition promotes the development of a healthy or healthier gut microbiome. The composition comprises 10%-70% Lactobacillus plantarum, Lactobacillus reuteri and mixtures thereof; 2%-86% plant sterols; and 4%-88% Ashwagandha root powder.

Abstract: Devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A device for supporting a medicament cartridge can comprise a body portion resembling a tray, with recesses disposed therein to support one or more of a cartridge body, cartridge tubing, interconnect fitting, and vial adapter. The recesses of the tray may be shaped to correspond to that component intended to be placed in its respective recess so to provide a visual indication to a user how to couple and align the various components necessary to fill the cartridge.

Abstract: The present invention related to the proline rich transmembrane protein 2 (PRRT2) gene, and the identification of mutations and variations in PRRT2 that give rise to seizure and movement disorders. Accordingly, the present invention provides methods for the diagnosis or prognosis of such disorders by identifying alterations in the PRRT2 gene. Identification of alterations in the PRRT2 gene also enables the identification of subjects with an increased likelihood of having an offspring predisposed to such disorders. The present invention also provides an isolated nucleic acid molecule comprising an alteration in the PRRT2 gene, wherein said alteration produces a seizure and/or movement disorder phenotype. Also provided is an isolated PRRT2 polypeptide that comprises an alteration which produces a seizure and/or movement disorder phenotype.

Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S or G12C. The compounds have a general Formula (I): (Formula (I)) wherein the variables of Formula (I) are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.

Abstract: A dispensing system for a floor treatment composition. The dispensing system includes a housing partially enclosing a cavity and a cradle moveable within the housing along a z-axis from a first position to a second position. The dispensing system further includes a chassis and a sliding lock that includes an open frame. An inlet canula projects through the open frame. When the cradle is in the second position, the inlet canula entrance projects through the open frame and through a liquid transport aperture in the cradle. Latches extending from the open frame also project through engagement apertures in the cradle when the cradle is in the second position. The dispensing system further includes a pump in fluid communication with the inlet canula and a mop head in fluid communication with the pump.

Abstract: The invention provides a composition comprising a colloidal particle comprising about 0.5 to 20 mole percent of an amphipathic lipid derivatized with a biocompatible hydrophilic polymer for use in medicine, wherein said composition does not contain any pharmaceutically active agent.

Abstract: A flow sensor assembly comprising a first substrate, a flow sensor located over the first substrate, a lid located over the first substrate and the flow sensor, a flow inlet channel, a flow outlet channel, and an overmold laterally encircling the flow sensor. The overmold is in contact with the side walls of the flow sensor, and extends between the flow sensor and the lid such that the overmold, the flow sensor, and the lid define a flow sensing channel between the flow inlet channel and the flow outlet channel. the lid and the encapsulation cooperate to define the flow inlet channel and the flow outlet channel.

Abstract: Techniques for data processing and control for a glucose monitoring system are provided, including obtaining a first sensitivity of a glucose sensor; obtaining a second sensitivity of the glucose sensor; comparing a difference between the first sensitivity and the second sensitivity to a predetermined range of values; if the difference is outside the predetermined range of the values, causing a calibration routine for the glucose sensor to be performed; and if the difference is within the predetermined range of values determining a composite sensitivity for a current calibration of the glucose sensor based on the first sensitivity and the second sensitivity and calculating the glucose level based on the current calibration of the glucose sensor.

Abstract: In one embodiment, a vehicle includes a steering wheel, one or more vehicle drive systems, one or more driving mode paddler shifters coupled to the steering wheel, an output device, and an electronic control unit. The electronic control unit is communicatively coupled to the one or more driving mode paddle shifters, the one or more vehicle drive systems, and the output device. The electronic control unit is configured to receive a drive mode shifting signal from the one or more driving mode paddle shifter indicative of a desire to change a driving mode of the vehicle, change one or more parameters of the one or more vehicle drive systems in order to change the driving mode in response to the driving mode shifting signal, and provide a notification related to the change in the driving mode with the output device.

Abstract: Methods of powering a radio that is mounted on a tower of a cellular base station are provided in which a direct current (“DC”) power signal is provided to the radio over a power cable and a voltage level of the output of the power supply is adjusted so as to provide a substantially constant voltage at a first end of the power cable that is remote from the power supply. Related cellular base stations and programmable power supplies are also provided.

Abstract: An optical network unit may include a light sensitive unit suitable for receiving NRZ and/or PAM signals effectively. The optical network unit may include a laser transmission unit for providing NRZ and/or PAM signals effectively.