Patents by Inventor John Charles Gebler

John Charles Gebler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 10490394
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: November 26, 2019
    Assignee: MICROMASS UK LIMITED
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20180012743
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: September 11, 2017
    Publication date: January 11, 2018
    Inventors: Weibin CHEN, Asish B. CHAKRABORTY, John Charles GEBLER, Jeffery Mark BROWN
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 9761425
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: September 12, 2017
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20150294846
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: June 26, 2015
    Publication date: October 15, 2015
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 9070539
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: June 30, 2015
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20140110576
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 8624179
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: January 7, 2014
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method Of Charge Reduction Of Electron Transfer Dissociation Product Ions
    Publication number: 20110114835
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: June 5, 2009
    Publication date: May 19, 2011
    Applicant: MICROMASS UK LIMITED
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • MALDI sample plate
    Patent number: 7294831
    Abstract: A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: November 13, 2007
    Assignee: Micromass UK Limited
    Inventors: Jeff Brown, Dominic Gostick, Edouard S. P. Bouvier, John Charles Gebler, Peter Jeng Jong Lee, James Ian Langridge, Emmanuelle Claude, Weibin Chen
  • Maldi sample plate
    Publication number: 20050274885
    Abstract: A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
    Type: Application
    Filed: August 3, 2005
    Publication date: December 15, 2005
    Applicant: Micromass UK Limited
    Inventors: Jeff Brown, Dominic Gostick, Edouard Bouvier, John Charles Gebler, Peter Jeng Jong Lee, James Ian Langridge, Emmanuelle Claude, Weibin Chen
  • MALDI sample plate
    Patent number: 6952011
    Abstract: A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: October 4, 2005
    Assignee: Micromass UK Limited
    Inventors: Jeff Brown, Dominic Gostick, Edouard S. P. Bouvier, John Charles Gebler, Peter Jeng Jong Lee, James Ian Langridge, Emmanuelle Claude, Weibin Chen
  • Maldi sample plate
    Publication number: 20030116707
    Abstract: A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
    Type: Application
    Filed: August 19, 2002
    Publication date: June 26, 2003
    Applicant: Micromass Limited
    Inventors: Jeff Brown, Dominic Gostick, Edouard S. P. Bouvier, John Charles Gebler, Peter Jeng Jong Lee, James Ian Langridge, Emmanuelle Claude, Weibin Chen