Abstract: The present disclosure relates to peptide having a sequence comprising: (SEQ?ID?NO:?1) Z1X1X2X3X4X5X6X7X8X9X10X11X12-NH2, and to their isomers, pharmaceutically acceptable salts, or prodrugs thereof, methods of use, and methods for their preparation. The peptides disclosed herein are useful for modulating orexin receptor activity and may be used in the treatment of disorders in which orexin receptor activity is implicated, such as narcolepsy, a hypersomnia disorder, a neurodegenerative disorder, a symptom of a rare genetic disorder, a mental health disorder, a metabolic syndrome, osteoporosis, cardiac failure, coma, or a complication in emergence from anaesthesia.

Abstract: Exemplary methods for facilitating secure communication between a mobile network subscriber and various service providers (SPs), the subscriber being associated with a plurality of entities comprising any combination of devices and profiles. Some embodiments can include: obtaining a security identifier associated with the subscriber; based on the security identifier, establishing an identity hierarchy comprising the plurality of entities associated with the subscriber; based on the security identifier, establishing consents for SPs to access data generated by the entities of the identity hierarchy; in response to a request comprising the security identifier, receiving a public key usable to encrypt data for sending to a particular SP, the data being decryptable using a corresponding secret key associated with an established consent for the particular SP; and encrypting the data using the public key and the identity hierarchy.

Abstract: Exemplary methods for facilitating secure communication between a mobile network subscriber and various service providers (SPs), the subscriber being associated with a plurality of entities comprising any combination of devices and profiles. Some embodiments can include: obtaining a security identifier associated with the subscriber; based on the security identifier, establishing an identity hierarchy comprising the plurality of entities associated with the subscriber; based on the security identifier, establishing consents for SPs to access data generated by the entities of the identity hierarchy; in response to a request comprising the security identifier, receiving a public key usable to encrypt data for sending to a particular SP, the data being decryptable using a corresponding secret key associated with an established consent for the particular SP; and encrypting the data using the public key and the identity hierarchy.

Abstract: The present invention generally relates to microfluidic droplets and, in particular, to multiple emulsion microfluidic droplets. In one set of embodiments, multiple emulsion droplets are provided, where an inner shell of the droplet is relatively thin, compared to the outer shell (or other shells) of the droplet. For instance, in one set of embodiments, the inner droplet has an average thickness of less than about 1000 nm. In some cases, the inner shell may be rigidified, e.g., to form a gel or a polymeric layer. This may be useful, for example, for preventing coalescence of fluids within the microfluidic droplet. Other embodiments of the present invention are generally directed to methods of making such droplets, methods of using such droplets, microfluidic devices for making such droplets, and the like.

Abstract: Systems and methods according to these exemplary embodiments provide for service personas to be added to network address books, in addition to personal contacts. Address book functionality can be leveraged by service providers to distribute their services and/or service updates to users. Users can leverage address book functionality to search for, register for, and screen updates from, a variety of services.

Abstract: A clicker is shown for giving an audible signal when an archer's bow string is properly tensioned. The clicker is mounted at the end of an elongated cable guard extension rod to cooperate with the rear edge of the connecting section of the string of a compound bow when the operative section of the string has been moved to its rearmost position, to indicate when the desired tension has been drawn in the string for shooting the arrow.