Patents by Inventor John Christopher Kappes

John Christopher Kappes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion protein delivery system and uses thereof
    Patent number: 6362000
    Abstract: The present invention provides a composition of matter, comprising: DNA encoding a viral Vpx protein fused to DNA encoding a protein. In another embodiment of the present invention, there is provided a composition of matter, comprising: DNA encoding a viral Vpr protein fused to DNA encoding a protein. The present invention further provides DNA, vectors and methods for expressing a lentiviral pol gene in trans, independent of the lentiviral gag-pol. A gene transduction element is optionally delivered to a lentiviral vector according to the present invention. Also provided are various methods of delivering a virus inhibitory molecule to a target in an animal. Further provided is a pharmaceutical composition.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: March 26, 2002
    Assignee: University of Alabama Research Foundation
    Inventors: John Christopher Kappes, Xiaoyun Wu
  • Fusion protein delivery systems and uses thereof
    Patent number: 6001985
    Abstract: The present invention provides a composition of matter, comprising: DNA encoding a viral Vpx protein fused to DNA encoding a virus inhibitory protein. In another embodiment of the present invention, there is provided a composition of matter, comprising: DNA encoding a viral Vpr protein fused to DNA encoding a virus inhibitory protein. Also provided are various methods of delivering a virus inhibitory molecule to a target in an animal. Further provided is a pharmaceutical composition.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: December 14, 1999
    Assignee: University of Alabama Research Foundation
    Inventors: John Christopher Kappes, Xiaoyun Wu