Patents by Inventor John Christopher Vederas

John Christopher Vederas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that stimulate glucose utilization and methods of use
    Patent number: 7084173
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia wherein W is C1–C6 alkyl, halogen, or aryl; Cyc is C3 or C4 cycloalkyl; p is 0–3 for Cyc being C4 cycloalkyl and p=0–2 for Cyc being C3 cycloalkyl; Y is O, S, or NR, where R?H, alkyl or aryl; X is O, S, NR, or CR3R4; Z is H, alkyl, cycloalkyl, aryl or (cyclo)alkylcarbonyl; R1 is H, alkyl, aryl or O; R2 is H, alkyl or aryl; R3 and R4 are, independently, H, alkyl or aryl; and n is an integer from 1 to 10; or a pharmaceutically acceptable salt, ester or prodrug thereof.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: August 1, 2006
    Assignee: The Governors of the Univerity of Alberta
    Inventors: Gary D. Lopaschuk, John Christopher Vederas, Jason R. Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Patent number: 7074828
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Grant
    Filed: December 5, 2002
    Date of Patent: July 11, 2006
    Assignee: The Governors of the University of Alberta
    Inventors: Gary David Lopaschuk, John Christopher Vederas, Jason Roland Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20040116517
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: 1
    Type: Application
    Filed: December 5, 2002
    Publication date: June 17, 2004
    Inventors: Gary David Lopaschuk, John Christopher Vederas, Jason Roland Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20030191182
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells.
    Type: Application
    Filed: April 9, 2003
    Publication date: October 9, 2003
    Inventors: Gary David Lopaschuk, John Christopher Vederas, Jason R Dyck
  • Process for the preparation of alkenoyl-substituted cyclohexenes
    Patent number: 3931323
    Abstract: New heterocyclic derivatives containing nitrogen useful for perfumery and the flavour industry and use of same as perfuming and/or flavouring ingredients in the manufacture of perfumes and perfumed products and/or in the preparation of artificial flavours for foodstuffs, beverages, animal feeds, pharmaceutical preparations and tobacco products.Process for preparing the said heterocyclic derivatives which are equally useful as starting materials for preparing known fragrance compounds.
    Type: Grant
    Filed: March 21, 1973
    Date of Patent: January 6, 1976
    Assignee: Firmenich SA
    Inventors: George Hermann Buchi, John Christopher Vederas