Abstract: A tubing connector system is configured to connect first and second pieces of medical tubing. The tubing connector system includes a male module and a female module. The female module is retained in connection to the male module by a plurality of locking mechanisms. The plurality of locking mechanisms are configured to prevent the male module and female module from being reconnected after the male module has been separated from the female module. The tubing connector system also includes a valve assembly that includes a first valve member contained within the male module and a second valve member contained within the female module. The first and second valve members are interconnected in a gimbaled relationship.