Patents by Inventor John Coller

John Coller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12258558
    Abstract: The disclosure is directed to methods and compositions for screening a library of aptamers for aptamers having a binding affinity to a target molecule. The methods and compositions described herein utilize a throughput approach that is able to simultaneously measure binding affinity and link the binding affinity to the identity (e.g., sequence) of the aptamer.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: March 25, 2025
    Assignees: CZ Biohub SF, LLC, The Board of Trustees of The Leland Stanford Junior University
    Inventors: Trevor Feagin, Diana Wu, Peter Mage, John Coller, Hyongsok Tom Soh
  • Publication number: 20210324374
    Abstract: The disclosure is directed to methods and compositions for screening a library of aptamers for aptamers having a binding affinity to a target molecule. The methods and compositions described herein utilize a throughput approach that is able to simultaneously measure binding affinity and link the binding affinity to the identity (e.g., sequence) of the aptamer.
    Type: Application
    Filed: June 4, 2019
    Publication date: October 21, 2021
    Inventors: Trevor Feagin, Diana Wu, Peter Mage, John Coller, Hyongsok Tom Soh
  • Publication number: 20060238855
    Abstract: The present invention provides a method and device for optically extracting discrete features of an object. With this method and device, small regions of interest or features within a relatively large object are optically extracted and collated into a single, condensed image. The condensed image contains all of the features in the original object, but not the parts of the object that are between the features. Thus, the optically extracted features can be viewed at high resolution, but in a limited field of view. Examples of objects that may be optically extracted according to the invention include spots of biomaterial on a biochip, material in wells of a microtiter plate, etc. In addition, this device and method can be used for non-planar objects. In this case, the device and method allow simultaneous visualization of spatially separated features on a surface of a 3-dimensional object.
    Type: Application
    Filed: January 6, 2006
    Publication date: October 26, 2006
    Inventors: John Coller, Michael Fero, Ian Hsu, Ching-Lung Huang
  • Patent number: 4055917
    Abstract: An inwardly swinging door is provided with a threshhold assembly that effectively seals against entry of driven water and air. The threshhold assembly includes a sloping subpan having an upstanding rear wall. An integral outer threshhold member and upper pan are connected to and above the subpan. The upper pan provides a primary seal at the front edge of the door bottom and defines a primary sill floor that cooperates with the flexible wiper blades carried by the door bottom to define secondary barriers. The inner side of the door bottom carries a final seal which bars entry of air that may be driven through drainage holes provided in the subpan and interconnecting the interior of the subpan with the interior of the upper pan.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: November 1, 1977
    Assignee: Elixir Industries
    Inventor: John Coller