Abstract: Embodiments include in response to monitoring a processor during operation, detecting a first number of core recovery events in the processor, determining that the first number of core recovery events fulfills a first condition for the first core recovery events threshold, and modifying a value of at least one droop sensor parameter of the processor by a first amount. The at least one droop sensor parameters affects a sensitivity to a voltage droop. In response to modifying the value of the droop sensor parameter by the first amount, a second number of core recovery events is detected in the processor. It is determined that the second number of core recovery events fulfills a second condition for a second core recovery events threshold, and the value of the at least one droop sensor parameter is modified by a second amount.

Abstract: Systems and methods described herein facilitate biometric, health, and activity data aggregation and visualization in order to provide improved physical performance tracking and medical monitoring. In some examples, the system can providing real time access to healthcare providers during telehealth sessions. In some examples, the system can include infectious disease monitoring, enabling a healthcare provider to monitor and provide healthcare to a group of patients outside of a clinical setting.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: According to some embodiments, a system comprises a generator of a truly random signal is connected to an input and feedback device for the purpose of providing a user with real time feedback on the random signal. The user observes a representation of the signal in the process of an external physical event for the purpose of finding a correlation between the random output and what happens during the physical event. In some examples, the system is preferably designed such the system is shielded from all classically known forces such as gravity, physical pressure, motion, electromagnetic fields, humidity, etc. and/or, such classical forces are factored out of the process as much as possible. The system is thus designed to be selectively response to signals from living creatures, in particular, humans.

Abstract: A method for changing a set point of a system where period of a dominant resonance of the system is determined, a change profile for the set point change is processed; a time period for the set point change based on the period of the dominant resonance in order to minimize excitation of the dominant resonance is also processed; and the set point change is actioned according to the processed change profile and the time period.

Abstract: The present disclosure generally pertains to a dispensing system comprising a first chamber capable of receiving a bulk material to be dispensed, a first set of finned shafts positioned within the first chamber and capable of feeding bulk material into a second chamber, and a second set of finned shafts positioned within the second chamber and capable of dispensing a controlled dose of bulk material from the second chamber.

Abstract: The appropriate scoping of an access policy can be determined using the observed access and usage of various resources covered under that policy. Information about access requests received over a period of time can be logged, and actions represented in the log data can be mapped to the permissions of the access policy. A new access policy can be generated that includes grant permissions only for those actions that were received and/or granted during the monitored period of time. The new policy can be processed using policy logic to ensure that changes in permission comply with rules or policies for the target resources. The new policy can be at least partially implemented, or can be provided to an authorized user, who can choose to adopt or deny the new policy, or to accept some of the recommendations for modifying the current policy.

Abstract: The appropriate scoping of an access policy can be determined using the observed access and usage of various resources covered under that policy. Information about access requests received over a period of time can be logged, and actions represented in the log data can be mapped to the permissions of the access policy. A new access policy can be generated that includes grant permissions only for those actions that were received and/or granted during the monitored period of time. The new policy can be processed using policy logic to ensure that changes in permission comply with rules or policies for the target resources. The new policy can be at least partially implemented, or can be provided to an authorized user, who can choose to adopt or deny the new policy, or to accept some of the recommendations for modifying the current policy.

Abstract: The present disclosure generally pertains to a dispensing system comprising an upper chamber capable of receiving a bulk material to be dispensed, a first set of finned shafts positioned within the upper chamber and capable of feeding bulk material into a lower chamber, and a second set of finned shafts positioned within the lower chamber and capable of dispensing a controlled dose of bulk material from the lower chamber.

Abstract: An apparatus, system and redox membrane for efficient lithium-ion extraction from natural salt waters or geothermal brines or manmade sources such as from lithium battery recycling are provided. The redox membrane is selective for lithium ions over other spectator ions making the system capable of selectively extracting lithium-ions from multiple-ion source solutions. The system uses the redox membrane as an electrochemically active material acting as a Li-selective membrane for direct lithium extraction from a lithium-ion source. The redox membrane is also not porous to solvents and is stable in caustic and high temperature environments. The features of the redox membrane and system allow the recovery of lithium from low purity sources and the production of higher purity products at reduced costs and process steps over conventional processes.

Abstract: This disclosure describes techniques for automating a system-level security review of a network-based service. The techniques may include generating and utilizing a machine-readable threat model to identify system-level security threats to the network-based service. The network-based service may be scanned upon being provisioned in a service-provider network, and the machine-readable threat model may be generated based on results of the scan. The machine-readable threat model may represent components of the network-based service, system-level security constraints configured to identify system-level security threats to the service, and mitigations to remedy violations to the system-level security constraints. The network-based service may be continuously, or periodically, scanned to identify changes in the network-based service.

Abstract: A screen stand to retrofit onto a stationary exercise machine using existing bolts on the stationary exercise machine. The screen stand has a hollow top mast slidably received within a hollow bottom mast. The bottom mast has a first anchor to attach to the pop pin of the stationary bicycle. There is a second anchor that attaches to the front stabilizer bar of the stationary bicycle.

Abstract: Methods and systems relating to a file distribution scheme in a computer network are disclosed that distributes files in an efficient manner that reduces, among other things, network traffic. In an embodiment of the invention, a method for updating a file is disclosed. In such a method, unique chunks in a first version of a digital file are identified. For a second version of the digital file, chunks that are the same as in the first version are identified. Recompilation information is generated and stored for these identified chunks. Also, for the second version of the digital file, chunks in the second version that are different from chunks in the first version are identified. Recompilation information is generated and stored for these identified chunks. With this information, the second version of the digital file is completely defined and can be efficiently stored.

Abstract: It is provided a charged particle beam manipulation device for a plurality of charged particle beamlets, the charged particle beam manipulation device including a lens having a main optical axis, the lens including at least a first array of multipoles, each multipole of the first array of multipoles configured to compensate for a lens deflection force on a respective charged particle beamlet of the plurality of charged particle beamlets, the lens deflection force being a deflection force produced by the lens on the respective charged particle beamlet towards the main optical axis of the lens.

Abstract: A computer-implemented method for the automated execution of vehicle functions of a vehicle includes: providing a vehicle function processing sequence which specifies a processing sequence of vehicle functions on the occurrence of a first triggering event, wherein the first triggering event is based on communication from a communication-enabled infrastructure device; checking for the occurrence of the first triggering event; on the occurrence of the first triggering event, generating control signals for controlling vehicle function devices in accordance with the vehicle function processing sequence; and outputting the generated control signals to the vehicle function devices executing the vehicle functions. In addition, a system for the automated execution of vehicle functions of a vehicle is provided.

Abstract: A submersible (10) and method of using a submersible for capturing a target species comprising: at least one controllable thruster (14) for manoeuvring the submersible; at least one camera (12) for capturing images to allow the identification of an individual of a target species; a catapult mechanism (33) wherein the catapult mechanism is reversibly moveable between a released configuration and a primed configuration by an activatable motor, and wherein the catapult mechanism may be loaded with a retractable device mounted on the catapult mechanism, and the retractable device may be launched from the submersible by being propelled by the catapult mechanism; a container for receiving a captured individual.

Abstract: Security policies may be utilized to grant or deny permissions related to the access of computing resources. Two or more security policies may be compared to determine whether the policies are equivalent, whether one security is more permissive than another, and more. In some cases, it may be possible to identify whether there exists a security permission that is sufficient to determine two security policies lack equivalency. Propositional logics may be utilized in the evaluation of security policies.

Abstract: For use in a reciprocating floor slat conveyor system having formed slats made of steel, a gap filler for sealing the gaps between side-by-side steel slats includes a portion that extends upwardly into the gap, and a lower portion that is connected to one of the side-by-side slats. The gap filler is installed by pushing down the gap filler into the gap between slats.