Abstract: Compositions and methods for treating a cancer in mammals by administering selective estrogen receptor modulators particularly compounds represented by: or any other of the structures contained herein, or of a stereoisomer, enantiomer, rotomer, tautomer or pharmaceutically acceptable salt form thereof.

Abstract: A method of treating cancer in warm-blooded animals by administering a safe and effective amount of a pharmaceutical composition comprising compounds selected from the group consisting of the compounds of Structure I Wherein: R1 and R2 are individually selected from the group consisting of alkyl groups containing 1 to 8 carbon atoms, taken together with nitrogen form a saturated 5 to 6 ring heterocycle, R3 is ? or ? methyl, n is an integer from 2 to 10, R4 is selected from the group consisting of hydrogen, hydroxy and acyloxy of a organic carboxylic acid of up to 10 carbon atoms or taken together with the nitrogen form a saturated 5 to 6 ring heterocycle optionally containing a second nitrogen or oxygen in the ring, carboxylic acid and R5 selected from the group consisting of hydrogen, hydroxy, acyloxy of a organic carboxylic acid up to 10 carbons atoms and alkyl, alkenyl and alkynyl of up to 10 carbons, R6 and R7 are individually selected from the group consisting of hydrogen, hydroxy and acyloxy o