Patents by Inventor John COUKOS

John COUKOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR ACTIVATING NRF2-DEPENDENT GENE EXPRESSION
    Publication number: 20250017898
    Abstract: Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
    Type: Application
    Filed: June 11, 2024
    Publication date: January 16, 2025
    Applicant: THE UNIVERSITY OF CHICAGO
    Inventors: Raymond MOELLERING, John COUKOS, Gihoon LEE, Jae Won CHANG, Gokhan MUTLU
  • Compositions and methods for activating NRF2-dependent gene expression
    Patent number: 12048686
    Abstract: Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: July 30, 2024
    Assignee: The University of Chicago
    Inventors: Raymond Moellering, John Coukos, Gihoon Lee, Jae Won Chang, Gokhan Mutlu
  • COMPOSITIONS AND METHODS FOR ACTIVATING NRF2-DEPENDENT GENE EXPRESSION
    Publication number: 20220031656
    Abstract: Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 3, 2022
    Applicant: The University of Chicago
    Inventors: Raymond MOELLERING, John COUKOS, Gihoon LEE, Jae Won CHANG, Gokhan MUTLU