Abstract: An apparatus and method for error correction based on soft decision bits and multiple hypotheses includes: maintaining a plurality of previous single bit-flip hypotheses, each hypothesis including a respective bit-flip, a respective pre-flip bit confidence, and a respective hash responsive to the respective bit-flip; receiving a bit and a corresponding bit confidence; comparing the received bit confidence with a highest pre-flip bit confidence of the maintained plurality of single bit-flip hypotheses; and if the received bit confidence is less than the highest pre-flip bit confidence, forming a new single bit-flip hypothesis and replacing a prior bit-flip hypothesis having the highest pre-flip bit confidence with the new hypothesis.

Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.

Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.

Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.

Abstract: A data bus interface may include a history buffer and a serializer. The history buffer may store bits representing a history of data recently transmitted on the data bus. The serializer may be configured to modify an input bit sequence containing original bits by interspersing padding bits with the original bits to suppress noise at one or more target frequencies. The serializer may output the modified input bit sequence on the data bus. Each padding bit of the plurality of padding bits may be generated based on values of at least two bits stored in the history buffer.

Abstract: A data bus interface may include a history buffer and a serializer. The history buffer may store bits representing a history of data recently transmitted on the data bus. The serializer may be configured to modify an input bit sequence containing original bits by interspersing padding bits with the original bits to suppress noise at one or more target frequencies. The serializer may output the modified input bit sequence on the data bus. Each padding bit of the plurality of padding bits may be generated based on values of at least two bits stored in the history buffer.

Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.

Abstract: A micro-etalon having non-beveled outer edges may be mass-produced without suffering from expected breakage problems. Such a configuration allows etalons to be mass-produced, i.e., on a wafer level. The mass-production preferably includes aligning spacer block strips to be diced with two reflective surfaces to form the etalon.