Patents by Inventor John D. Alvey
John D. Alvey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10945446Abstract: A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.25 g/100 Kcal to 16 g/100 Kcal of buttermilk; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.Type: GrantFiled: January 30, 2020Date of Patent: March 16, 2021Assignee: MEAD JOHNSON NUTRITION COMPANYInventors: Zihua Ao, Carol Lynn Berseth, Patricia Cobb, Juan M. Gonzalez, Elisha London, Minhthy Nguyen, James David Richards, Colin Rudolph, John D. Alvey, Yadilka Maldonado, Chenzhong Kuang, Yan Xiao, Dirk Hondmann
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Publication number: 20200163354Abstract: A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.25 g/100 Kcal to 16 g/100 Kcal of buttermilk; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.Type: ApplicationFiled: January 30, 2020Publication date: May 28, 2020Inventors: Zihua Ao, Carol Lynn Berseth, Patricia Cobb, Juan M. Gonzalez, Elisha London, Minhthy Nguyen, James David Richards, Colin Rudolph, John D. Alvey, Yadilka Maldonado, Chenzhong Kuang, Yan Xiao, Dirk Hondmann
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Patent number: 10582714Abstract: A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.25 g/100 Kcal to 16 g/100 Kcal of buttermilk; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.Type: GrantFiled: October 14, 2015Date of Patent: March 10, 2020Assignee: MEAD JOHNSON NUTRITION COMPANYInventors: Zihua Ao, Carol Lynn Berseth, Patricia Cobb, Juan M. Gonzalez, Elisha London, Minhthy Nguyen, James David Richards, Colin Rudolph, John D. Alvey, Yadilka Maldonado, Chenzhong Kuang, Yan Xiao, Dirk Hondmann
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Patent number: 10455854Abstract: The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.Type: GrantFiled: May 2, 2017Date of Patent: October 29, 2019Assignee: MEAD JOHNSON NUTRITION COMPANYInventors: Dattatreya Banavara, John D. Alvey, Juan M. Gonzalez
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Publication number: 20170231262Abstract: The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.Type: ApplicationFiled: May 2, 2017Publication date: August 17, 2017Inventors: Dattatreya Banavara, John D. Alvey, Juan M. Gonzalez
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Patent number: 9671271Abstract: The disclosure relates to a measuring device for a granulated product, including a top component comprising a leveling component and a clump-breaking component and a bottom component comprising a scoop and a handle. The measuring device allows a user to remove excess product from the scoop by moving the leveling component along the opening of the scoop. Further, the clump-breaking component serves to break the clump of product that forms in the scoop upon dispensing the product from the measuring device into a receptacle, which may contain a liquid. Breaking the clump of product improves the dissolution of the product into a liquid.Type: GrantFiled: October 14, 2016Date of Patent: June 6, 2017Assignee: Mead Johnson Nutrition CompanyInventor: John D. Alvey
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Patent number: 9661868Abstract: The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed adsorption column comprising a particulate matrix, applying a milk source to the matrix, and eluting the lactoferrin from the matrix with an elution buffer comprising about 0.3 to about 2.0 M sodium chloride.Type: GrantFiled: July 16, 2013Date of Patent: May 30, 2017Assignee: Mead Johnson Nutrition CompanyInventors: Dattatreya Banavara, John D. Alvey, Joseph Andrew Peters, Juan M. Gonzalez
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Publication number: 20170006898Abstract: A method for enhancing cognitive development in a pediatric subject involving administering to the subject a nutritional composition which includes up to 7 g/100 Kcal of a fat or lipid; up to 5 g/100 Kcal of a protein or protein equivalent source; 0.25 g/100 Kcal to 16 g/100 Kcal of buttermilk; 5 mg/100 Kcal to 90 mg/100 Kcal of a source of long chain polyunsaturated fatty acid; and 0.015 g/100 Kcal to 1.5 g/100 Kcal of a prebiotic.Type: ApplicationFiled: October 14, 2015Publication date: January 12, 2017Inventors: Zihua Ao, Carol Lynn Berseth, Patricia Cobb, Juan M. Gonzalez, Elisha London, Minhthy Nguyen, James David Richards, Colin Rudolph, John D. Alvey, Yadilka Maldonado
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Publication number: 20160345611Abstract: The present disclosure relates to nutritional composition(s) containing a protein equivalent source which includes a rice protein hydrolysate, and an octenyl succinic anhydride (OSA) modified starch emulsifier. The disclosure also relates to method(s) of producing rice protein hydrolysate, the method(s) including suspending rice protein in a solution to form a suspension; heating the suspension; cooling the heated suspension; adding an endoprotease to the suspension to hydrolyze the rice protein into at least two supernatant fractions; inactivating the endoprotease; separating an insoluble portion of the suspension from the at least two supernatant fractions; collecting the at least two supernatant fractions; and combining the at least two supernatant fractions.Type: ApplicationFiled: May 28, 2015Publication date: December 1, 2016Inventors: Juan M. Gonzalez, John D. Alvey, Zihua Ao, Cristine Bradley, Robert Cleveland, Jennifer Kinnaman
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Patent number: 9375028Abstract: The present disclosure provides compositions and methods for delivering nutrients to subjects requiring small-volume nutritional support, such as preterm infants. The compositions may comprise an emulsion of docosahexaenoic acid (DHA) and arachidonic acid (ARA). The nutritional compositions are useful, for example, in correcting nutritional deficiencies by increasing a subject's intake of nutrients, such as ?-3 or ?-6 long-chain polyunsaturated acids. The nutritional compositions are suitable for enteral delivery as a nutritional supplement or for oral delivery as a human milk or infant formula fortifier.Type: GrantFiled: December 9, 2010Date of Patent: June 28, 2016Assignee: Mead Johnson Nutrition CompanyInventors: John D. Alvey, Carol Lynn Berseth, Deborah Schade, Kristin Morris
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Patent number: 8986769Abstract: The present invention is directed to a processing method and a selection of ingredients that will retain TGF-? levels, bioactivity, and/or bioavailability in a liquid nutritional product. The method involves selecting one or more protein ingredients that have been subjected to a heat load comprising medium-heat or less; combining the protein ingredients with other components of the liquid nutritional product to form a slurry; subjecting the slurry to a pressure of from about 2500 psi to about 3500 psi at a temperature of from about 55° C. to about 65° C. for about 5 to 20 seconds; subjecting the slurry to a temperature of about 135 to 150° C. for about 1.5 to 15 seconds; and cooling the slurry to a temperature of less than about 8° C. over about 30 minutes or less.Type: GrantFiled: February 12, 2009Date of Patent: March 24, 2015Assignee: Mead Johnson Nutrition CompanyInventors: Juan M. Gonzalez, Dattatreya Banavara, John D. Alvey
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Publication number: 20150024462Abstract: The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed adsorption column comprising a particulate matrix, applying a milk source to the matrix, and eluting the lactoferrin from the matrix with an elution buffer comprising about 0.3 to about 2.0 M sodium chloride.Type: ApplicationFiled: July 16, 2013Publication date: January 22, 2015Inventors: Dattatreya Banavara, John D. Alvey, Joseph Andrew Peters, Juan M. Gonzalez
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Patent number: 8652096Abstract: An ingestible material delivery device for sequentially delivering first and second ingestible materials to a user through a feeding tube provides a tube body having first and second chambers separated by a seal. A puncture tool is disposed in the second chamber extending toward the seal. The puncture tool engages and disrupts the seal when the second chamber is compressed. In some embodiments, the second chamber includes a plurality of interconnected bellows operable for axial compression of the second chamber. Another embodiment of a delivery device provides a tube body having first and second chambers with exit nozzles extending in opposite flow directions. A method of sequentially delivering first and second ingestible materials to a user through a feeding tube is also provided.Type: GrantFiled: February 21, 2011Date of Patent: February 18, 2014Assignee: Mead Johnson Nutrition CompanyInventors: John D. Alvey, Marc S. Velmer
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Patent number: 8622974Abstract: A plunger-driven delivery device for use with a feeding tube for delivering an ingestible material to a user is provided. The delivery device includes a device body having a first chamber, a second chamber and an exit orifice through which the ingestible material is delivered to the feeding tube. A first plunger is disposed in the first chamber, and a second plunger is disposed in the second chamber. The delivery device can be provided with the ingestible material disposed in the first chamber and a flushing liquid disposed in the second chamber. The delivery device is operable to provide sequential delivery first of the ingestible material and then the flushing liquid into the feeding tube. In some embodiments, a mechanical interlock is disposed between the first and second plungers to prevent use of the second plunger until the first plunger has been depressed.Type: GrantFiled: February 21, 2011Date of Patent: January 7, 2014Assignee: Mead Johnson Nutrition CompanyInventors: John D. Alvey, Marc S. Velmer
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Publication number: 20120215205Abstract: A plunger-driven delivery device for use with a feeding tube for delivering an ingestible material to a user is provided. The delivery device includes a device body having a first chamber, a second chamber and an exit orifice through which the ingestible material is delivered to the feeding tube. A first plunger is disposed in the first chamber, and a second plunger is disposed in the second chamber. The delivery device can be provided with an ingestible material disposed in the first chamber and a flushing liquid disposed in the second chamber. The delivery device is operable to provide sequential delivery first of ingestible material and then flushing liquid into a feeding tube. In some embodiments, a mechanical interlock is disposed between the first and second plungers to prevent use of the second plunger until the first plunger has been depressed.Type: ApplicationFiled: February 21, 2011Publication date: August 23, 2012Inventors: John D. Alvey, Mare S. Velmer
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Publication number: 20120171328Abstract: A method for preparing compositions comprising heat labile milk proteins is disclosed herein. In certain embodiments, the method involves subjecting a first composition comprising a fat or lipid source and a protein source to a temperature of at least about 130° C. and combining the first composition with a second composition comprising a heat labile milk protein. In another embodiment, the method includes combining a first composition comprising a fat or lipid source and a protein source that has been subjected to a temperature of at least about 130° C. with a composition comprising a heat labile milk protein to form a third composition including a fat or lipid source, a protein source and a heat labile milk protein and packaging the third composition aseptically.Type: ApplicationFiled: January 5, 2011Publication date: July 5, 2012Inventors: Dattatreya Banavara, John D. Alvey, Juan M. Gonzalez
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Publication number: 20120149774Abstract: The present disclosure provides compositions and methods for delivering nutrients to subjects requiring small-volume nutritional support, such as preterm infants. The compositions may comprise an emulsion of docosahexaenoic acid (DHA) and arachidonic acid (ARA). The nutritional compositions are useful, for example, in correcting nutritional deficiencies by increasing a subject's intake of nutrients, such as ?-3 or ?-6 long-chain polyunsaturated acids. The nutritional compositions are suitable for enteral delivery as a nutritional supplement or for oral delivery as a human milk or infant formula fortifier.Type: ApplicationFiled: December 9, 2010Publication date: June 14, 2012Inventors: John D. Alvey, Carol Lynn Berseth, Deborah Schade, Kristin Morris