Patents by Inventor John D. Bradley
John D. Bradley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10233462Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root knot nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets show significant conservation at the nucleotide level between orthologs from different Meloidogyne species, facilitating genus-wide targeting by RNA interference.Type: GrantFiled: March 7, 2017Date of Patent: March 19, 2019Assignee: Monsanto Technology LLCInventors: John D. Bradley, Brandi J. Chiapelli, Bingli Gao, James P. McCarter, Michelle L. Gasper, Deryck Jeremy Williams
-
Patent number: 9790516Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Pratylenchus (root lesion nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets are conserved and expected to be essential and sensitive to RNAi perturbation in different Pratylenchus species, facilitating genus-wide targeting by RNA interference.Type: GrantFiled: November 6, 2014Date of Patent: October 17, 2017Assignee: Monsanto Technology LLCInventors: Brandi Chiapelli, Matt W. Dimmic, Deryck Jeremy Williams, Jennifer Sheppard, John D. Bradley, Carl Diehl, Michelle L. Gasper, Bingli Gao, James P. McCarter
-
Publication number: 20170247718Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root knot nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets show significant conservation at the nucleotide level between orthologs from different Meloidogyne species, facilitating genus-wide targeting by RNA interference.Type: ApplicationFiled: March 7, 2017Publication date: August 31, 2017Inventors: John D. Bradley, Brandi J. Chiapelli, Bingli Gao, James P. McCarter, Michelle L. Gasper, Deryck Jeremy Williams
-
Patent number: 9624508Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root knot nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets show significant conservation at the nucleotide level between orthologs from different Meloidogyne species, facilitating genus-wide targeting by RNA interference.Type: GrantFiled: October 1, 2014Date of Patent: April 18, 2017Assignee: Monsanto Technology LLCInventors: John D. Bradley, Brandi J. Chiapelli, Bingli Gao, James P. McCarter, Michelle L. Gasper, Deryck Jeremy Williams
-
Publication number: 20150203866Abstract: The present invention is directed to controlling nematode infestation. The invention discloses methods and compositions for use in controlling nematode infestation by providing recombinant DNA molecules to the cells of a plant in order to achieve a reduction in nematode infestation. The invention is also directed to methods for making transgenic plants that express the recombinant DNA molecule for use in protecting plants from nematode infestation.Type: ApplicationFiled: March 9, 2015Publication date: July 23, 2015Inventors: John D. Bradley, Catherine C. Baublite, Michael J. Crawford, Stanislaw Flasinski, Deryck J. Williams
-
Publication number: 20150135363Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Pratylenchus (root lesion nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets are conserved and expected to be essential and sensitive to RNAi perturbation in different Pratylenchus species, facilitating genus-wide targeting by RNA interference.Type: ApplicationFiled: November 6, 2014Publication date: May 14, 2015Inventors: Brandi Chiapelli, Matt W. Dimmic, Deryck Jeremy Williams, Jennifer Sheppard, John D. Bradley, Carl Diehl, Michelle L. Gasper, Bingli Gao, James P. McCarter
-
Patent number: 9006517Abstract: The present invention is directed to controlling nematode infestation. The invention discloses methods and compositions for use in controlling nematode infestation by providing recombinant DNA molecules to the cells of a plant in order to achieve a reduction in nematode infestation. The invention is also directed to methods for making transgenic plants that express the recombinant DNA molecule for use in protecting plants from nematode infestation.Type: GrantFiled: February 9, 2009Date of Patent: April 14, 2015Assignee: Monsanto Technology LLCInventors: John D. Bradley, Catherine C. Baublite, Michael J. Crawford, Stanislaw Flasinski, Deryck J. Williams
-
Patent number: 8907162Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Pratylenchus (root lesion nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets are conserved and expected to be essential and sensitive to RNAi perturbation in different Pratylenchus species, facilitating genus-wide targeting by RNA interference.Type: GrantFiled: December 29, 2010Date of Patent: December 9, 2014Assignee: Monsanto Technology LLCInventors: Brandi Chiapelli, Matt W. Dimmic, Deryck Jeremy Williams, Jennifer Sheppard, John D. Bradley, Carl Diehl, Michelle L. Gasper, Bingli Gao, James P. McCarter
-
Patent number: 8901373Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root knot nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets show significant conservation at the nucleotide level between orthologs from different Meloidogyne species, facilitating genus-wide targeting by RNA interference.Type: GrantFiled: April 10, 2009Date of Patent: December 2, 2014Assignee: Monsanto Technology LLCInventors: John D. Bradley, Brandi J. Chiapelli, Bingli Gao, James P. McCarter, Michelle L. Gasper, Deryck Jeremy Williams
-
Publication number: 20130036519Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Pratylenchus (root lesion nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets are conserved and expected to be essential and sensitive to RNAi perturbation in different Pratylenchus species, facilitating genus-wide targeting by RNA interference.Type: ApplicationFiled: December 29, 2010Publication date: February 7, 2013Applicant: Monsanto Technology LLCInventors: Brandi Chiapelli, Matt W. Dimmic, Deryck Jeremy Williams, Jennifer Sheppard, John D. Bradley, Carl Diehl, Michelle L. Gasper, Bingli Gao, James P. McCarter
-
Patent number: 8198060Abstract: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.Type: GrantFiled: October 28, 2008Date of Patent: June 12, 2012Assignee: Divergence, Inc.Inventors: Deryck J. Williams, Merry B. McLaird, Michelle Coutu Hresko, Anita M. Frevert, Ronald E. Worthington, Andrew P. Kloek, Jennifer A. Davila-Aponte, John D. Bradley, Siqun Xu
-
Publication number: 20120030834Abstract: The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root knot nematodes). The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences in the cells of plant-parasitic nematodes. The disclosed gene targets show significant conservation at the nucleotide level between orthologs from different Meloidogyne species, facilitating genus-wide targeting by RNA interference.Type: ApplicationFiled: April 10, 2009Publication date: February 2, 2012Inventors: John D. Bradley, Brandi Chiapelli, Bingli Gao, James P. McCarter, Michelle L. Verbsky, Deryck Jeremy Williams
-
Patent number: 7993894Abstract: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.Type: GrantFiled: January 15, 2009Date of Patent: August 9, 2011Assignee: Divergence, Inc.Inventors: Andrew P. Kloek, Deryck J. Williams, Merry B. McLaird, John D. Bradley, Jennifer A. DaVila-Aponte, Siqun Xu, Anita M. Frevert
-
Publication number: 20110107446Abstract: The present invention is directed to controlling nematode infestation. The invention discloses methods and compositions for use in controlling nematode infestation by providing recombinant DNA molecules to the cells of a plant in order to achieve a reduction in nematode infestation. The invention is also directed to methods for making transgenic plants that express the recombinant DNA molecule for use in protecting plants from nematode infestation.Type: ApplicationFiled: February 9, 2009Publication date: May 5, 2011Inventors: John D. Bradley, Catherine C. Baublite, Michael J. Crawford, Stanislaw Flasinski, Deryck J. Williams
-
Patent number: 7867749Abstract: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.Type: GrantFiled: January 5, 2006Date of Patent: January 11, 2011Assignee: Divergence, Inc.Inventors: Deryck J. Williams, Merry B. McLaird, Michelle Coutu Hresko, Anita M. Frevert-Thompson, Ronald E. Worthington, Andrew P. Kloek, Jennifer A. Davila-Aponte, John D. Bradley, Siqun Xu
-
Publication number: 20100248357Abstract: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.Type: ApplicationFiled: January 15, 2009Publication date: September 30, 2010Inventors: Andrew P. Kloek, Deryck J. Williams, Merry B. McLaird, John D. Bradley, Jennifer A. DaVila-Aponte, Siqun Xu, Anita M. Frevert
-
Patent number: 7666642Abstract: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.Type: GrantFiled: January 15, 2009Date of Patent: February 23, 2010Assignee: Divergence, Inc.Inventors: Andrew P. Kloek, Deryck J. Williams, Merry B. McLaird, John D. Bradley, Jennifer A. Davila-Aponte, Siqun Xu, Anita M. Frevert
-
Publication number: 20090318563Abstract: Certain ethanolamine analogs and related compounds useful in the control of nematodes that infest plants or the situs of plants are described.Type: ApplicationFiled: December 23, 2008Publication date: December 24, 2009Inventors: Michelle Coutu Hresko, Deryck J. Williams, Merry B. McLaird, John D. Bradley, Barry J. Shortt, Ronald E. Worthington
-
Publication number: 20090203127Abstract: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as arc vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.Type: ApplicationFiled: January 15, 2009Publication date: August 13, 2009Inventors: Andrew P. Kloek, Deryck J. Williams, Merry B. McLaird, John D. Bradley, Jennifer A. Davila-Aponte, Siqun Xu, Anita M. Frevert
-
Publication number: 20090123986Abstract: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.Type: ApplicationFiled: October 28, 2008Publication date: May 14, 2009Inventors: Deryck J. Williams, Merry B. McLaird, Michelle Coutu Hresko, Anita M. Frevert, Ronald E. Worthington, Andrew P. Kloek, Jennifer A. Davila-Aponte, John D. Bradley, Siqun Xu