Patents by Inventor John D. Bu'Lock

John D. Bu'Lock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5840704
    Abstract: The invention provides novel compounds having the formula: ##STR1## wherein R when taken individually is H; R.sup.1 when taken individually is H or OH; R and R.sup.1 when taken together represent a double bond;R.sup.2 is an alpha-branched C.sub.3 -C.sub.8 alkyl, alkenyl, alkynyl, alkoxyalkyl or alkylthioalkyl group; a C.sub.3 -C.sub.8 cycloalkyl, C.sub.5 -C.sub.8 cycloalkenyl or C.sub.5 -C.sub.8 cycloalkylalkyl group, any of which may be substituted by methylene or one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms; or a 3 to 6 membered oxygen or sulphur containing heterocyclic ring which may be substituted by one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms;R.sup.3 is hydrogen or methyl;R.sup.4 is H or 4'-(alpha-L-oleandrosyl)-alpha-L-oleandrosyloxy with the proviso that when R.sup.2 is alkyl it is not isopropyl or sec-butyl; when R.sup.4 is H, each of R and R.sup.1 is H, and R.sup.2 is not methyl or ethyl; and when R.sup.
    Type: Grant
    Filed: March 23, 1993
    Date of Patent: November 24, 1998
    Assignee: Pfizer Inc.
    Inventors: Stephen P. Gibson, Alexander C. Goudie, Kelvin S. Holdom, John D. Bu'Lock
  • Patent number: 5451511
    Abstract: The invention provides novel compounds having the formula: ##STR1## wherein R when taken individually is H; R.sup.1 when taken individually is H or OH; R and R.sup.1 when taken together represent a double bond;R.sup.2 is an alpha-branched C.sub.3 -C.sub.8 alkyl, alkenyl, alkynyl, alkoxyalkyl or alkylthioalkyl group; a C.sub.3 -C.sub.8 cycloalkyl, C.sub.5 -C.sub.8 cycloalkenyl or C.sub.5 -C.sub.8 cycloalkylalkyl group, any of which may be substituted by methylene or one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms; or a 3 to 6 membered oxygen or sulphur containing heterocyclic ring which may be substituted by one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms;R.sup.3 is hydrogen or methyl;R.sup.4 is H or 4'-(alpha-L-oleandrosyl)-alpha-L-oleandrosyloxy with the proviso that when R.sup.2 is alkyl it is not isopropyl or sec-butyl; when R.sup.4 is H, each of R and R.sup.1 is H, and R.sup.2 is not methyl or ethyl; and when R.sup.4 is H, R is H, R.sup.1 is OH, and R.sup.
    Type: Grant
    Filed: March 9, 1993
    Date of Patent: September 19, 1995
    Assignee: Pfizer Inc.
    Inventors: Stephen P. Gibson, Alexander C. Goudie, Kelvin S. Holdom, John D. Bu'Lock
  • Patent number: 5089480
    Abstract: The invention provides novel compounds having the formula: ##STR1## wherein R when taken individually is H; R.sup.1 when taken individually is H or OH; R and R.sup.1 when taken together represent a double bond;R.sup.2 is an alpha-branched C.sub.3 -C.sub.8 alkyl, alkenyl, alkynyl, alkoxyalkyl or alkylthioalkyl group; a C.sub.3 -C.sub.8 cycloalkyl, C.sub.5 -C.sub.8 cycloalkenyl or C.sub.5 -C.sub.8 cycloalkylalkyl group, any of which may be substituted by methylene or one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms; or a 3 to 6 membered oxygen or sulphur containing heterocyclic ring which may be substituted by one or more C.sub.1 -C.sub.4 alkyl groups or halo atoms;R.sup.3 is hydrogen or methyl;R.sup.4 is H or 4'-(alpha-L-oleandrosyl)-alpha-L-oleandrosyloxy with the proviso that when R.sup.2 is alkyl it is not isopropyl or sec-butyl; when R.sup.4 is H, each of R and R.sup.1 is H, and R.sup.2 is not methyl or ethyl; and when R.sup.4 is H, R is H, R.sup.1 is OH, and R.sup.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: February 18, 1992
    Assignee: Pfizer Inc.
    Inventors: Stephen P. Gibson, Alexander C. Goudie, Kelvin S. Holdom, John D. Bu'lock
  • Patent number: 5008383
    Abstract: Novel surface-active compositions are prepared by reacting a diketene prepared from a fatty acid or fatty acid chloride with 8-22 carbon atoms with a substance having a hydrophlic moiety and a hydroxyl or amino group containing one or more active hydrogens. The active hydrogen-containing group is acylated by the diketene and the resulting product contains the hydrophillic moiety and also branched 2-alkyl-3-ketoacyl chains.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: April 16, 1991
    Assignee: 31 Research Exploitation Limited
    Inventors: John D. Bu'lock, James K. Sutherland, Michael J. Donnelly
  • Patent number: 4357424
    Abstract: A process for the continuous production of fermentation alcohol, by effecting fermentation of a continuous or substantially continuous supply of the liquid substrate by a dense suspension of a suitable micro-organism in a reaction column wherein the suspension is maintained in a well mixed state. The mixture passes from the upper region of the reaction column into a degassing zone where less turbulent conditions readily permit degassing of the mixture, causing part of the degassed mixture to flow into a settling zone wherein quiescent conditions permit the biomass to settle out. The settled biomass is returned to the bottom of the reaction column to assist in the continuation of the fermentation process. Gases evolving from the top of the reaction column and from the tops of the degassing and settling zones are removed.
    Type: Grant
    Filed: December 2, 1980
    Date of Patent: November 2, 1982
    Assignee: Sim-Chem Limited
    Inventor: John D. Bu'Lock